Category: 66947-92-0

66947-92-0, Name is Methyl 2-amino-1,3-benzothiazole-6-carboxylate, molecular formula is C9H8N2O2S, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 66947-92-0, Safety of Methyl 2-amino-1,3-benzothiazole-6-carboxylate

Provided is a phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt can selectively inhibit the protein-protein interaction between KRS and a laminin receptor (LR), thereby inhibiting migration of cancer cells. Therefore, the phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt may be usefully applied for preventing or treating the diseases associated with cancer cell metastasis.

Provided is a phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt can selectively inhibit the protein-protein interaction between KRS and a laminin receptor (LR), thereby inhibiting migration of cancer cells. Therefore, the phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt may be usefully applied for preventing or treating the diseases associated with cancer cell metastasis.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Safety of Methyl 2-amino-1,3-benzothiazole-6-carboxylate. In my other articles, you can also check out more blogs about 66947-92-0

Reference£º
Thiazole | C3H8392NS – PubChem,
Thiazole | chemical compound | Britannica

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.66947-92-0,Methyl 2-amino-1,3-benzothiazole-6-carboxylate,as a common compound, the synthetic route is as follows.

To a stirred mixture of VIII-2 (600 mg, 2.28 mmol) and CuBr2 (775 mg, 3.46 mmol) in MeCN (9 mL) was added tert-butyl nitrite (445 mg, 4.32 mmol). The reaction mixture was stirred at rt overnight. The mixture was diluted with EtOAc (40 mL), washed with water and brine, dried over Na2SO4, filtered and concentrated. The residue was purified by column (PE:EA=5:1) to give VIII-3 (140 mg, yield: 18%)., 66947-92-0

As the paragraph descriping shows that 66947-92-0 is playing an increasingly important role.

Reference£º
Patent; Buckman, Brad Owen; Nicholas, John Beamond; Emayan, Kumaraswamy; Seiwert, Scott D.; US2014/200215; (2014); A1;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica