In an article, published in an article, once mentioned the application of 875798-81-5, Name is tert-Butyl (5-(2-aminoethyl)thiazol-2-yl)carbamate,molecular formula is C10H17N3O2S, is a conventional compound. this article was the specific content is as follows.name: tert-Butyl (5-(2-aminoethyl)thiazol-2-yl)carbamate
This communication describes the discovery of a novel series of Aurora kinase inhibitors. Key SAR and critical binding elements are discussed. Some of the more advanced analogues potently inhibit cellular proliferation and induce phenotypes consistent with Aurora kinase inhibition. In particular, compound 21 (SNS-314) is a potent and selective Aurora kinase inhibitor that exhibits significant activity in pre-clinical in vivo tumor models.
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Reference£º
Thiazole | C3H9070NS – PubChem,
Thiazole | chemical compound | Britannica