Downstream synthetic route of 1003-32-3

1003-32-3 Thiazole-5-carboxyaldehyde 2773577, athiazole compound, is more and more widely used in various.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1003-32-3,Thiazole-5-carboxyaldehyde,as a common compound, the synthetic route is as follows.

EXAMPLE 93 The process is performed as in Example 92 but starting with 0.45 g of 5-thiazolecarboxaldehyde, 0.45 g of 5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one, 0.2 g of ammonium acetate and 4 ml of acetic anhydride. 0.35 g of 10-(5-thiazolylmethylene)-5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one is obtained in the form of a dark red solid melting above 260 C. (Analysis, % calculated C: 64.14, H: 3.17, N: 17.60, O: 5.03, S: 10.07, % found C: 64.2, N: 17.2, S: 9.7).

1003-32-3 Thiazole-5-carboxyaldehyde 2773577, athiazole compound, is more and more widely used in various.

Reference£º
Patent; Rhone-Poulenc Rorer S.A.; US5807859; (1998); A;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica