Tag: 156.2486

Formation of azomethines from 2-aminothiazoles and (heterocyclic) aromatic aldehydes was written by Hopkinson, Christopher;Meakins, George Denis;Purcell, Roberts James. And the article was included in Synthesis in 1991.HPLC of Formula: 74370-93-7 This article mentions the following:

Reexamination of previous work and new studies show that the reactions of 2-aminothiazoles with (heterocyclic) aromatic aldehydes are not straightforward; there are wide divergencies in behavior between the various amine-aldehyde pairs. Simple efficient procedures for preparing 2-(alkylideneamino)thiazole derivatives I (R¹ = H, R² = 2-thienyl, 2-furyl, Ph, 4-O₂NC₆H₄, 4-MeOC₆H₄; R¹ = Me, CMe₃, Ph, R² = 4-MeOC₆H₄, 4-Me₂NC₆H₄, 4-C₂NC₆H₄) and [bis(thiazol-2-ylamino)methyl]arenes II were developed. In the experiment, the researchers used many compounds, for example, 4-(tert-Butyl)thiazol-2-amine (cas: 74370-93-7HPLC of Formula: 74370-93-7).

4-(tert-Butyl)thiazol-2-amine (cas: 74370-93-7) belongs to thiazole derivatives. The thiazole ring has been identified as a central feature of numerous natural products, perhaps the most famous example of which is epothilone. There are numerous natural products that possess a thiazole ring with broad pharmacological activities. Thiamine, also known as vitamin B1, possesses a thiazole ring linked with 2-methylpyrimidine-4-amine as hydrochloride salt.HPLC of Formula: 74370-93-7

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Copper Acetate-Catalyzed, Mild, Highly Efficient, and Practical Synthesis of Thiazoles and Aminothiazoles was written by Meshram, H. M.;Kumar, D. Aravind;Vara Prasad, B. Ramalinga. And the article was included in Synthetic Communications in 2009.Application of 74370-93-7 This article mentions the following:

A mild and highly efficient synthesis of thiazoles by the condensation of 伪-bromo ketones with thiourea in the presence of a catalytic amount of copper acetate at room temperature has been described. The method is applicable for a variety of aryl and alkyl 伪-bromo ketones. The catalyst is inexpensive, and substituted thiazoles are obtained in good yields. In the experiment, the researchers used many compounds, for example, 4-(tert-Butyl)thiazol-2-amine (cas: 74370-93-7Application of 74370-93-7).

4-(tert-Butyl)thiazol-2-amine (cas: 74370-93-7) belongs to thiazole derivatives. Thiazole rings are planar and aromatic. Thiazoles are characterized by larger pi-electron delocalization than the corresponding oxazoles and have therefore greater aromaticity.Various laboratory methods exist for the organic synthesis of thiazoles. For example, 2,4-dimethylthiazole is synthesized from thioacetamide and chloroacetone.Application of 74370-93-7

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Formation of azomethines from 2-aminothiazoles and (heterocyclic) aromatic aldehydes was written by Hopkinson, Christopher;Meakins, George Denis;Purcell, Roberts James. And the article was included in Synthesis in 1991.HPLC of Formula: 74370-93-7 This article mentions the following:

Reexamination of previous work and new studies show that the reactions of 2-aminothiazoles with (heterocyclic) aromatic aldehydes are not straightforward; there are wide divergencies in behavior between the various amine-aldehyde pairs. Simple efficient procedures for preparing 2-(alkylideneamino)thiazole derivatives I (R¹ = H, R² = 2-thienyl, 2-furyl, Ph, 4-O₂NC₆H₄, 4-MeOC₆H₄; R¹ = Me, CMe₃, Ph, R² = 4-MeOC₆H₄, 4-Me₂NC₆H₄, 4-C₂NC₆H₄) and [bis(thiazol-2-ylamino)methyl]arenes II were developed. In the experiment, the researchers used many compounds, for example, 4-(tert-Butyl)thiazol-2-amine (cas: 74370-93-7HPLC of Formula: 74370-93-7).

4-(tert-Butyl)thiazol-2-amine (cas: 74370-93-7) belongs to thiazole derivatives. The thiazole ring has been identified as a central feature of numerous natural products, perhaps the most famous example of which is epothilone. There are numerous natural products that possess a thiazole ring with broad pharmacological activities. Thiamine, also known as vitamin B1, possesses a thiazole ring linked with 2-methylpyrimidine-4-amine as hydrochloride salt.HPLC of Formula: 74370-93-7

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Copper Acetate-Catalyzed, Mild, Highly Efficient, and Practical Synthesis of Thiazoles and Aminothiazoles was written by Meshram, H. M.;Kumar, D. Aravind;Vara Prasad, B. Ramalinga. And the article was included in Synthetic Communications in 2009.Application of 74370-93-7 This article mentions the following:

A mild and highly efficient synthesis of thiazoles by the condensation of α-bromo ketones with thiourea in the presence of a catalytic amount of copper acetate at room temperature has been described. The method is applicable for a variety of aryl and alkyl α-bromo ketones. The catalyst is inexpensive, and substituted thiazoles are obtained in good yields. In the experiment, the researchers used many compounds, for example, 4-(tert-Butyl)thiazol-2-amine (cas: 74370-93-7Application of 74370-93-7).

4-(tert-Butyl)thiazol-2-amine (cas: 74370-93-7) belongs to thiazole derivatives. Thiazole rings are planar and aromatic. Thiazoles are characterized by larger pi-electron delocalization than the corresponding oxazoles and have therefore greater aromaticity.Various laboratory methods exist for the organic synthesis of thiazoles. For example, 2,4-dimethylthiazole is synthesized from thioacetamide and chloroacetone.Application of 74370-93-7

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica