Tag: 192.24

Ghorbani-Vaghei, Ramin et al. published their research in Applied Organometallic Chemistry in 2018 | CAS: 57634-55-6

4-(2-Amino-4-thiazolyl)phenol (cas: 57634-55-6) belongs to thiazole derivatives. The higher aromaticity of thiazole is due to delocalization of a lone pair of sulfur electrons across the ring, which is evidenced by chemical shifts of ring hydrogen at 未 7.27 and 8.77 ppm (C2 and C4), indicating diamagnetic ring current. Thiazole is a versatile building block for the construction and lead generation of new drug discoveries. Numerous diazole-based compounds are in clinical use as anticancer, antileukemic, antiinflammatory, antiviral, antifungal, antirheumatic, immunomodulator, and antiparasitic agents.Formula: C9H8N2OS

MNPs@SiO2-Pr-AP: A new catalyst for the synthesis of 2-amino-4-aryl thiazole derivatives was written by Ghorbani-Vaghei, Ramin;Alavinia, Sedigheh;Merati, Zohreh;Izadkhah, Vida. And the article was included in Applied Organometallic Chemistry in 2018.Formula: C9H8N2OS This article mentions the following:

Magnetically recoverable nano-magnetic catalyst supported with functionalized (n-propyl)-4-amino-pyridine silica (MNPs@SiO2-Pr-AP) was synthesized and characterized using different techniques. A simple and efficient synthesis of 2-amino-4-aryl thiazoles I [R = H, 4-Cl, 3-NO2, etc, X = CH, N] was described via condensation of acetophenones and thiourea using three different types of catalytic systems including N,N,N’,N’-tetrabromobenzene-1,3-disulfonamide [TBBDA], poly(N,N’-dibromo-N-ethylbenzene-1,3-disulfonamide) [PBBS] and a combination of TBBDA and MNPs@SiO2-Pr-AP. The results showed that, the use of TBBDA along with the MNPs@SiO2-Pr-AP gains the highest yields of the products in the shortest reaction time. In the experiment, the researchers used many compounds, for example, 4-(2-Amino-4-thiazolyl)phenol (cas: 57634-55-6Formula: C9H8N2OS).

4-(2-Amino-4-thiazolyl)phenol (cas: 57634-55-6) belongs to thiazole derivatives. The higher aromaticity of thiazole is due to delocalization of a lone pair of sulfur electrons across the ring, which is evidenced by chemical shifts of ring hydrogen at 未 7.27 and 8.77 ppm (C2 and C4), indicating diamagnetic ring current. Thiazole is a versatile building block for the construction and lead generation of new drug discoveries. Numerous diazole-based compounds are in clinical use as anticancer, antileukemic, antiinflammatory, antiviral, antifungal, antirheumatic, immunomodulator, and antiparasitic agents.Formula: C9H8N2OS

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Rahatgaonkar, Anjali et al. published their research in Asian Journal of Chemistry in 2006 | CAS: 57634-55-6

4-(2-Amino-4-thiazolyl)phenol (cas: 57634-55-6) belongs to thiazole derivatives. Thiazoles are a class of five-membered rings containing nitrogen and sulfur with excellent antitumor, antiviral and antibiotic activities. Thiazole sulfonation occurs only under forcing conditions: the action of oleum at 250 掳C for 3 hours in the presence of mercury(II) sulfate leads to 65% formation of 5-thiazole sulfonic acid.SDS of cas: 57634-55-6

Microwave-assisted synthesis of 2-amino-4-substituted phenyl-thiazole was written by Rahatgaonkar, Anjali;Rathod, A.. And the article was included in Asian Journal of Chemistry in 2006.SDS of cas: 57634-55-6 This article mentions the following:

The reaction time needed to synthesize substituted 2-amino-4-phenyl-thiazole was substantially reduced from hours to minutes by microwave irradiation Microwave assisted techniques have many advantages, i.e., very rapid reactions, low energy consumption and safe operation, high yield and less time. In the experiment, the researchers used many compounds, for example, 4-(2-Amino-4-thiazolyl)phenol (cas: 57634-55-6SDS of cas: 57634-55-6).

4-(2-Amino-4-thiazolyl)phenol (cas: 57634-55-6) belongs to thiazole derivatives. Thiazoles are a class of five-membered rings containing nitrogen and sulfur with excellent antitumor, antiviral and antibiotic activities. Thiazole sulfonation occurs only under forcing conditions: the action of oleum at 250 掳C for 3 hours in the presence of mercury(II) sulfate leads to 65% formation of 5-thiazole sulfonic acid.SDS of cas: 57634-55-6

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Rahatgaonkar, Anjali et al. published their research in Asian Journal of Chemistry in 2006 | CAS: 57634-55-6

4-(2-Amino-4-thiazolyl)phenol (cas: 57634-55-6) belongs to thiazole derivatives. Thiazoles are a class of five-membered rings containing nitrogen and sulfur with excellent antitumor, antiviral and antibiotic activities. Thiazole sulfonation occurs only under forcing conditions: the action of oleum at 250 °C for 3 hours in the presence of mercury(II) sulfate leads to 65% formation of 5-thiazole sulfonic acid.SDS of cas: 57634-55-6

Microwave-assisted synthesis of 2-amino-4-substituted phenyl-thiazole was written by Rahatgaonkar, Anjali;Rathod, A.. And the article was included in Asian Journal of Chemistry in 2006.SDS of cas: 57634-55-6 This article mentions the following:

The reaction time needed to synthesize substituted 2-amino-4-phenyl-thiazole was substantially reduced from hours to minutes by microwave irradiation Microwave assisted techniques have many advantages, i.e., very rapid reactions, low energy consumption and safe operation, high yield and less time. In the experiment, the researchers used many compounds, for example, 4-(2-Amino-4-thiazolyl)phenol (cas: 57634-55-6SDS of cas: 57634-55-6).

4-(2-Amino-4-thiazolyl)phenol (cas: 57634-55-6) belongs to thiazole derivatives. Thiazoles are a class of five-membered rings containing nitrogen and sulfur with excellent antitumor, antiviral and antibiotic activities. Thiazole sulfonation occurs only under forcing conditions: the action of oleum at 250 °C for 3 hours in the presence of mercury(II) sulfate leads to 65% formation of 5-thiazole sulfonic acid.SDS of cas: 57634-55-6

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Vom, Amelia et al. published their research in Australian Journal of Chemistry in 2013 | CAS: 57634-55-6

4-(2-Amino-4-thiazolyl)phenol (cas: 57634-55-6) belongs to thiazole derivatives. Thiazoles are a class of five-membered rings containing nitrogen and sulfur with excellent antitumor, antiviral and antibiotic activities. Various laboratory methods exist for the organic synthesis of thiazoles. Prominent is the Hantzsch thiazole synthesis is a reaction between haloketones and thioamides.Recommanded Product: 4-(2-Amino-4-thiazolyl)phenol

Detection and Prevention of Aggregation-based False Positives in STD-NMR-based Fragment Screening was written by Vom, Amelia;Headey, Stephen;Wang, Geqing;Capuano, Ben;Yuriev, Elizabeth;Scanlon, Martin J.;Simpson, Jamie S.. And the article was included in Australian Journal of Chemistry in 2013.Recommanded Product: 4-(2-Amino-4-thiazolyl)phenol This article mentions the following:

Aggregation of small organic compounds is a problem encountered in a variety of assay screening formats where it often results in detection of false positives. A saturation transfer difference-NMR-detected screen of a com. available fragment library, followed by biochem. assay, identified several inhibitors of the enzyme ketopantoate reductase. These inhibitors were subsequently revealed to be aggregation-based false positives. Modification of the fragment screen by addition of detergent in the saturation transfer difference-NMR experiments allowed an assay format to be developed that resulted in the identification of genuine hit mols. suitable for further development. In the experiment, the researchers used many compounds, for example, 4-(2-Amino-4-thiazolyl)phenol (cas: 57634-55-6Recommanded Product: 4-(2-Amino-4-thiazolyl)phenol).

4-(2-Amino-4-thiazolyl)phenol (cas: 57634-55-6) belongs to thiazole derivatives. Thiazoles are a class of five-membered rings containing nitrogen and sulfur with excellent antitumor, antiviral and antibiotic activities. Various laboratory methods exist for the organic synthesis of thiazoles. Prominent is the Hantzsch thiazole synthesis is a reaction between haloketones and thioamides.Recommanded Product: 4-(2-Amino-4-thiazolyl)phenol

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Ghorbani-Vaghei, Ramin et al. published their research in Applied Organometallic Chemistry in 2018 | CAS: 57634-55-6

4-(2-Amino-4-thiazolyl)phenol (cas: 57634-55-6) belongs to thiazole derivatives. The higher aromaticity of thiazole is due to delocalization of a lone pair of sulfur electrons across the ring, which is evidenced by chemical shifts of ring hydrogen at δ 7.27 and 8.77 ppm (C2 and C4), indicating diamagnetic ring current. Thiazole is a versatile building block for the construction and lead generation of new drug discoveries. Numerous diazole-based compounds are in clinical use as anticancer, antileukemic, antiinflammatory, antiviral, antifungal, antirheumatic, immunomodulator, and antiparasitic agents.Formula: C9H8N2OS

MNPs@SiO2-Pr-AP: A new catalyst for the synthesis of 2-amino-4-aryl thiazole derivatives was written by Ghorbani-Vaghei, Ramin;Alavinia, Sedigheh;Merati, Zohreh;Izadkhah, Vida. And the article was included in Applied Organometallic Chemistry in 2018.Formula: C9H8N2OS This article mentions the following:

Magnetically recoverable nano-magnetic catalyst supported with functionalized (n-propyl)-4-amino-pyridine silica (MNPs@SiO2-Pr-AP) was synthesized and characterized using different techniques. A simple and efficient synthesis of 2-amino-4-aryl thiazoles I [R = H, 4-Cl, 3-NO2, etc, X = CH, N] was described via condensation of acetophenones and thiourea using three different types of catalytic systems including N,N,N’,N’-tetrabromobenzene-1,3-disulfonamide [TBBDA], poly(N,N’-dibromo-N-ethylbenzene-1,3-disulfonamide) [PBBS] and a combination of TBBDA and MNPs@SiO2-Pr-AP. The results showed that, the use of TBBDA along with the MNPs@SiO2-Pr-AP gains the highest yields of the products in the shortest reaction time. In the experiment, the researchers used many compounds, for example, 4-(2-Amino-4-thiazolyl)phenol (cas: 57634-55-6Formula: C9H8N2OS).

4-(2-Amino-4-thiazolyl)phenol (cas: 57634-55-6) belongs to thiazole derivatives. The higher aromaticity of thiazole is due to delocalization of a lone pair of sulfur electrons across the ring, which is evidenced by chemical shifts of ring hydrogen at δ 7.27 and 8.77 ppm (C2 and C4), indicating diamagnetic ring current. Thiazole is a versatile building block for the construction and lead generation of new drug discoveries. Numerous diazole-based compounds are in clinical use as anticancer, antileukemic, antiinflammatory, antiviral, antifungal, antirheumatic, immunomodulator, and antiparasitic agents.Formula: C9H8N2OS

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Rahatgaonkar, Anjali et al. published their research in Asian Journal of Chemistry in 2006 | CAS: 57634-55-6

4-(2-Amino-4-thiazolyl)phenol (cas: 57634-55-6) belongs to thiazole derivatives. Thiazoles are a class of five-membered rings containing nitrogen and sulfur with excellent antitumor, antiviral and antibiotic activities. Thiazole sulfonation occurs only under forcing conditions: the action of oleum at 250 °C for 3 hours in the presence of mercury(II) sulfate leads to 65% formation of 5-thiazole sulfonic acid.SDS of cas: 57634-55-6

Microwave-assisted synthesis of 2-amino-4-substituted phenyl-thiazole was written by Rahatgaonkar, Anjali;Rathod, A.. And the article was included in Asian Journal of Chemistry in 2006.SDS of cas: 57634-55-6 This article mentions the following:

The reaction time needed to synthesize substituted 2-amino-4-phenyl-thiazole was substantially reduced from hours to minutes by microwave irradiation Microwave assisted techniques have many advantages, i.e., very rapid reactions, low energy consumption and safe operation, high yield and less time. In the experiment, the researchers used many compounds, for example, 4-(2-Amino-4-thiazolyl)phenol (cas: 57634-55-6SDS of cas: 57634-55-6).

4-(2-Amino-4-thiazolyl)phenol (cas: 57634-55-6) belongs to thiazole derivatives. Thiazoles are a class of five-membered rings containing nitrogen and sulfur with excellent antitumor, antiviral and antibiotic activities. Thiazole sulfonation occurs only under forcing conditions: the action of oleum at 250 °C for 3 hours in the presence of mercury(II) sulfate leads to 65% formation of 5-thiazole sulfonic acid.SDS of cas: 57634-55-6

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica