With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.19759-66-1,2-Aminobenzothiazole-6-carbonitrile,as a common compound, the synthetic route is as follows.
19759-66-1, General procedure: A mixture of intermediate 4 (10 mmol), potassium carbonate (12 mmol) and various 2-aminobenzothiazoles (10 mmol) in acetone solvent (30 mL) was refluxed for 8 h. The progress of the reaction was monitored by TLC. After cooling to room temperature, the reaction mixture was treated with 200 mL cold water, and the resulting precipitate was filtered off. The crude products 5a-j were recrystallized from DMF.
As the paragraph descriping shows that 19759-66-1 is playing an increasingly important role.
Reference£º
Article; Patel, Amit B.; Raval, Rinku M.; Research on Chemical Intermediates; vol. 42; 3; (2016); p. 2163 – 2175;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica