Cyclometalated Half-Sandwich Iridium Complex for Catalytic Hydrogenation of Imines and Quinolines was written by Yao, Zi-Jian;Lin, Nan;Qiao, Xin-Chao;Zhu, Jing-Wei;Deng, Wei. And the article was included in Organometallics in 2018.Category: thiazole This article mentions the following:
Several C,N-chelate cyclometalated half-sandwich iridium-based catalysts [Cp*IrCl(2-ArBztz)] (1–5, H-ArBztz = arylbenzothiazole) for imines and quinoline derivatives reduction have been prepared through metal-mediated C-H bond activation based on benzothiazole ligands. These iridium complexes exhibited high catalytic activity for hydrogenation of various types of imines with high yields. The most active catalyst was obtained from methoxy substituted complex [2, HArBztz = 2-(4-methoxyphenyl)benzothiazole] showing the catalytic TOF value of 975 h-1 for the reduction of N-phenylacetophenoneketimine (6a). Addnl., these half-sandwich complexes also showed high efficiency for the catalytic hydrogenation of N-heterocyclic quinoline derivatives Good catalytic activity was displayed for various kinds of substrates with either electron-donating or electron-withdrawing groups. Complexes 1–5 were fully characterized by NMR, IR, and elemental anal. Mol. structures of complexes 1 (ArH = Ph) and 4 (ArH = 4-ClC6H4) were further confirmed by X-ray diffraction anal. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenyl)benzothiazole (cas: 6265-92-5Category: thiazole).
2-(4-Methoxyphenyl)benzothiazole (cas: 6265-92-5) belongs to thiazole derivatives. Thiazoles are a class of five-membered rings containing nitrogen and sulfur with excellent antitumor, antiviral and antibiotic activities. Electrophilic attack at nitrogen depends on the presence of electron density at nitrogen as well as the position and nature of substituent linked to the thiazole ring.Category: thiazole
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica