Tag: 255.3167

Sewerage surveillance tracking characteristics of human antibiotic emission in sewage was written by Dong, Qian;Cheng, Zhao;Yuan, Zhiguo;Huang, Xia;Liu, Yanchen. And the article was included in Journal of Cleaner Production in 2022.Synthetic Route of C9H9N3O2S2 This article mentions the following:

Antibiotics discharging are causing the concerns of public health and sustainable production Further policies on antibiotic production and antibiotic sales are difficult to make when lacking of sewage surveillance. In this study, the dynamic occurrence of 24 typical antibiotics in urban sewerage was investigated throughout a whole year. It was found that 17 of 42 samples had a total antibiotic concentration of more than 1000 ng/L. Sulfonamides, lincosamides, macrolides and tetracyclines were the four most common antibiotic categories in sewerage system, with the average concentration of 1246 ng/L, 2418 ng/L, 1734 ng/L and 1140 ng/L, resp. The concentration of 尾-lactams was relatively low in the raw sewage (with the median value of 11 ng/L) and exhibited a tendency of attenuation in sewerage due to its degradability. The total concentration of antibiotics in sewage in different quarters were pos. correlated with the dosage of antibiotics prescribed by local hospitals (R = 0.88, p < 0.01). The antibiotics profiles were also determined by the local regional discharge, specific seasons and weather features. Antibiotics consumption significantly affects the level of antibiotic residues in sewage, indicating that sewage surveillance can provide rough information on antibiotic usage. These findings can lead to new ways to understand the actual antibiotic usage in humans, and guide the antibiotic production and usage based on sewage surveillance. In the experiment, the researchers used many compounds, for example, 4-Amino-N-(thiazol-2-yl)benzenesulfonamide (cas: 72-14-0Synthetic Route of C9H9N3O2S2).

4-Amino-N-(thiazol-2-yl)benzenesulfonamide (cas: 72-14-0) belongs to thiazole derivatives. The thiazole ring is notable as a component of the vitamin thiamine (B1). Thiazole sulfonation occurs only under forcing conditions: the action of oleum at 250 掳C for 3 hours in the presence of mercury(II) sulfate leads to 65% formation of 5-thiazole sulfonic acid.Synthetic Route of C9H9N3O2S2

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Changes of antibiotic occurrence and hydrochemistry in groundwater under the influence of the South-to-North Water Diversion (the Hutuo River, China) was written by Wang, Jialin;Zhang, Chong;Xiong, Ling;Song, Guangdong;Liu, Fei. And the article was included in Science of the Total Environment in 2022.Quality Control of 4-Amino-N-(thiazol-2-yl)benzenesulfonamide This article mentions the following:

The occurrence of antibiotics in groundwater has significant spatial variability, owing to the complexity of pollutant properties, pollution sources and groundwater recharge and discharge conditions. This study aimed to identify the relationship between antibiotic occurrence and hydrochem. in groundwater. Thus, we undertook this study in a characteristic alluvial-diluvial aquifer where groundwater receives unidirectional recharge from surface water. In total, 47 samples were collected from the Hutuo River before and after an artificial replenishment project. We screened up to four classes of antibiotics and detected 28 types. The statistical anal. of antibiotic concentrations, indicated that there were two pollution areas. Next, we discussed the results pertaining to the occurrence and source of antibiotics by comparing them with hydrochem. data. In the study area, a pos. correlation has been found between inorganic compounds, as SO₄^2-and Cl^–, and the most mobile antibiotics given that both share the same source. This shows that a previous sound geochem. study may provide evidence of the extend of antibiotic occurrence, as in the Hutuo River aquifer. The relationship between antibiotics and hydrochem. in groundwater is determined by recharge sources (rainwater and surface water contaminated with antibiotics). Antibiotics from wastewater treatment plants enter groundwater indirectly through surface water with high SO₄^2- in lightly polluted areas, while in heavily polluted areas, there are high concentrations of inorganic components in garbage leachate and wastewater leakage that carry antibiotics directly into groundwater. In summarized, the relationship between antibiotics and hydrochem. observed in this study shows that a previous sound geochem. study may provide evidence of the extend of antibiotic occurrence. In the experiment, the researchers used many compounds, for example, 4-Amino-N-(thiazol-2-yl)benzenesulfonamide (cas: 72-14-0Quality Control of 4-Amino-N-(thiazol-2-yl)benzenesulfonamide).

4-Amino-N-(thiazol-2-yl)benzenesulfonamide (cas: 72-14-0) belongs to thiazole derivatives. Thiazole is a five-membered, unsaturated, planar, 蟺-excessive heteroaromatic containing one sulfur atom and one pyridine-type nitrogen atom at position 3 of the cyclic ring system. Thiazole sulfonation occurs only under forcing conditions: the action of oleum at 250 掳C for 3 hours in the presence of mercury(II) sulfate leads to 65% formation of 5-thiazole sulfonic acid.Quality Control of 4-Amino-N-(thiazol-2-yl)benzenesulfonamide

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Impacts of nano-zero-valent iron on antibiotic removal by anaerobic membrane bioreactor for swine wastewater treatment was written by Liu, Wancen;Xia, Ruohan;Ding, Xiangrui;Cui, Wenjing;Li, Tianzhi;Li, Guoxue;Luo, Wenhai. And the article was included in Journal of Membrane Science in 2022.Related Products of 72-14-0 This article mentions the following:

This study investigated the impact of nano-zero-valent iron (nZVI) on the removal of veterinary antibiotics by an anaerobic membrane bioreactor (AnMBR) for swine wastewater treatment. Ten veterinary antibiotics belonged to three commonly used groups, namely tetracyclines, fluoroquinolones, and sulfonamides, were evaluated. Results show that nZVI addition could improve AnMBR performance for the removal of both phosphorus and ammonium. Moreover, nZVI addition to AnMBR could improve the biodegradation of antibiotics to enhance their overall removal. Of the three groups of antibiotics, the enhancement was most obvious for sulfonamides with an increase in the removal rate from 32 – 62% to 64-97% when 2.6 g L^-1 nZVI was added to AnMBR. Further microbial and redundancy analyses indicate that the removal of sulfonamides was closely and pos. correlated to the relative abundance of the genera Lentimicrobium and Methanomethylovorans. By contrast, nZVI reduced the removal of tetracycline, ciprofloxacin, and norfloxacin by AnMBR. Microbial anal. showed that nZVI dosage slightly reduced methane yield by promoting the growth of Mesotoga but reducing the proliferation of Methanomassiliicoccus to potentially disrupt the hydrogenotrophic pathway. In addition, adding nZVI reduced the ratios of protein to polysaccharide in both extracellular polymeric substances and soluble microbial products, thereby mitigating membrane fouling. In the experiment, the researchers used many compounds, for example, 4-Amino-N-(thiazol-2-yl)benzenesulfonamide (cas: 72-14-0Related Products of 72-14-0).

4-Amino-N-(thiazol-2-yl)benzenesulfonamide (cas: 72-14-0) belongs to thiazole derivatives. The higher aromaticity of thiazole is due to delocalization of a lone pair of sulfur electrons across the ring, which is evidenced by chemical shifts of ring hydrogen at 未 7.27 and 8.77 ppm (C2 and C4), indicating diamagnetic ring current. Thiazole is a versatile building block for the construction and lead generation of new drug discoveries. Numerous diazole-based compounds are in clinical use as anticancer, antileukemic, antiinflammatory, antiviral, antifungal, antirheumatic, immunomodulator, and antiparasitic agents.Related Products of 72-14-0

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

The human health implications of antibiotic resistance in environmental isolates from two nebraska watersheds was written by Donner, Linsey;Staley, Zachery R.;Petali, Jonathan;Sangster, Jodi;Li, Xu;Mathews, Wayne;Snow, Daniel;Howe, Adina;Soupir, Michelle;Bartelt-Hunt, Shannon. And the article was included in Microbiology Spectrum in 2022.Recommanded Product: 4-Amino-N-(thiazol-2-yl)benzenesulfonamide This article mentions the following:

One Health field-based approaches are needed to connect the occurrence of antibiotics present in the environment with the presence of antibiotic resistance genes (ARGs) in Gram-neg. bacteria that confer resistance to antibiotics important in for both veterinary and human health. Water samples from two Nebraska watersheds influenced by wastewater effluent and agricultural runoff were tested for the presence of antibiotics used in veterinary and human medicine. The water samples were also cultured to identify the bacteria present. Of those bacteria isolated, the Gram-neg. rods capable of causing human infections had antimicrobial susceptibility testing and whole-genome sequencing (WGS) performed to identify ARGs present. Of the 211 bacterial isolates identified, 37 belonged to pathogenic genera known to cause human infections. Genes conferring resistance to beta-lactams, aminoglycosides, fosfomycins, and quinolones were the most frequently detected ARGs associated with horizontal gene transfer (HGT) in the watersheds. WGS also suggest recent HGT events involving ARGs transferred between watershed isolates and bacteria of human and animal origins. The results of this study demonstrate the linkage of antibiotics and bacterial ARGs present in the environment with potential human and/or veterinary health impacts. In the experiment, the researchers used many compounds, for example, 4-Amino-N-(thiazol-2-yl)benzenesulfonamide (cas: 72-14-0Recommanded Product: 4-Amino-N-(thiazol-2-yl)benzenesulfonamide).

4-Amino-N-(thiazol-2-yl)benzenesulfonamide (cas: 72-14-0) belongs to thiazole derivatives. Thiazoles frequently appear in peptide studies. Thiazoles can also be used as protected formyl groups, which can be released in later stages of complex natural product synthesis.Various laboratory methods exist for the organic synthesis of thiazoles. For example, 2,4-dimethylthiazole is synthesized from thioacetamide and chloroacetone.Recommanded Product: 4-Amino-N-(thiazol-2-yl)benzenesulfonamide

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Sewerage surveillance tracking characteristics of human antibiotic emission in sewage was written by Dong, Qian;Cheng, Zhao;Yuan, Zhiguo;Huang, Xia;Liu, Yanchen. And the article was included in Journal of Cleaner Production in 2022.Synthetic Route of C9H9N3O2S2 This article mentions the following:

Antibiotics discharging are causing the concerns of public health and sustainable production Further policies on antibiotic production and antibiotic sales are difficult to make when lacking of sewage surveillance. In this study, the dynamic occurrence of 24 typical antibiotics in urban sewerage was investigated throughout a whole year. It was found that 17 of 42 samples had a total antibiotic concentration of more than 1000 ng/L. Sulfonamides, lincosamides, macrolides and tetracyclines were the four most common antibiotic categories in sewerage system, with the average concentration of 1246 ng/L, 2418 ng/L, 1734 ng/L and 1140 ng/L, resp. The concentration of β-lactams was relatively low in the raw sewage (with the median value of 11 ng/L) and exhibited a tendency of attenuation in sewerage due to its degradability. The total concentration of antibiotics in sewage in different quarters were pos. correlated with the dosage of antibiotics prescribed by local hospitals (R = 0.88, p < 0.01). The antibiotics profiles were also determined by the local regional discharge, specific seasons and weather features. Antibiotics consumption significantly affects the level of antibiotic residues in sewage, indicating that sewage surveillance can provide rough information on antibiotic usage. These findings can lead to new ways to understand the actual antibiotic usage in humans, and guide the antibiotic production and usage based on sewage surveillance. In the experiment, the researchers used many compounds, for example, 4-Amino-N-(thiazol-2-yl)benzenesulfonamide (cas: 72-14-0Synthetic Route of C9H9N3O2S2).

4-Amino-N-(thiazol-2-yl)benzenesulfonamide (cas: 72-14-0) belongs to thiazole derivatives. The thiazole ring is notable as a component of the vitamin thiamine (B1). Thiazole sulfonation occurs only under forcing conditions: the action of oleum at 250 °C for 3 hours in the presence of mercury(II) sulfate leads to 65% formation of 5-thiazole sulfonic acid.Synthetic Route of C9H9N3O2S2

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Changes of antibiotic occurrence and hydrochemistry in groundwater under the influence of the South-to-North Water Diversion (the Hutuo River, China) was written by Wang, Jialin;Zhang, Chong;Xiong, Ling;Song, Guangdong;Liu, Fei. And the article was included in Science of the Total Environment in 2022.Quality Control of 4-Amino-N-(thiazol-2-yl)benzenesulfonamide This article mentions the following:

The occurrence of antibiotics in groundwater has significant spatial variability, owing to the complexity of pollutant properties, pollution sources and groundwater recharge and discharge conditions. This study aimed to identify the relationship between antibiotic occurrence and hydrochem. in groundwater. Thus, we undertook this study in a characteristic alluvial-diluvial aquifer where groundwater receives unidirectional recharge from surface water. In total, 47 samples were collected from the Hutuo River before and after an artificial replenishment project. We screened up to four classes of antibiotics and detected 28 types. The statistical anal. of antibiotic concentrations, indicated that there were two pollution areas. Next, we discussed the results pertaining to the occurrence and source of antibiotics by comparing them with hydrochem. data. In the study area, a pos. correlation has been found between inorganic compounds, as SO₄^2-and Cl^–, and the most mobile antibiotics given that both share the same source. This shows that a previous sound geochem. study may provide evidence of the extend of antibiotic occurrence, as in the Hutuo River aquifer. The relationship between antibiotics and hydrochem. in groundwater is determined by recharge sources (rainwater and surface water contaminated with antibiotics). Antibiotics from wastewater treatment plants enter groundwater indirectly through surface water with high SO₄^2- in lightly polluted areas, while in heavily polluted areas, there are high concentrations of inorganic components in garbage leachate and wastewater leakage that carry antibiotics directly into groundwater. In summarized, the relationship between antibiotics and hydrochem. observed in this study shows that a previous sound geochem. study may provide evidence of the extend of antibiotic occurrence. In the experiment, the researchers used many compounds, for example, 4-Amino-N-(thiazol-2-yl)benzenesulfonamide (cas: 72-14-0Quality Control of 4-Amino-N-(thiazol-2-yl)benzenesulfonamide).

4-Amino-N-(thiazol-2-yl)benzenesulfonamide (cas: 72-14-0) belongs to thiazole derivatives. Thiazole is a five-membered, unsaturated, planar, π-excessive heteroaromatic containing one sulfur atom and one pyridine-type nitrogen atom at position 3 of the cyclic ring system. Thiazole sulfonation occurs only under forcing conditions: the action of oleum at 250 °C for 3 hours in the presence of mercury(II) sulfate leads to 65% formation of 5-thiazole sulfonic acid.Quality Control of 4-Amino-N-(thiazol-2-yl)benzenesulfonamide

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Impacts of nano-zero-valent iron on antibiotic removal by anaerobic membrane bioreactor for swine wastewater treatment was written by Liu, Wancen;Xia, Ruohan;Ding, Xiangrui;Cui, Wenjing;Li, Tianzhi;Li, Guoxue;Luo, Wenhai. And the article was included in Journal of Membrane Science in 2022.Related Products of 72-14-0 This article mentions the following:

This study investigated the impact of nano-zero-valent iron (nZVI) on the removal of veterinary antibiotics by an anaerobic membrane bioreactor (AnMBR) for swine wastewater treatment. Ten veterinary antibiotics belonged to three commonly used groups, namely tetracyclines, fluoroquinolones, and sulfonamides, were evaluated. Results show that nZVI addition could improve AnMBR performance for the removal of both phosphorus and ammonium. Moreover, nZVI addition to AnMBR could improve the biodegradation of antibiotics to enhance their overall removal. Of the three groups of antibiotics, the enhancement was most obvious for sulfonamides with an increase in the removal rate from 32 – 62% to 64-97% when 2.6 g L^-1 nZVI was added to AnMBR. Further microbial and redundancy analyses indicate that the removal of sulfonamides was closely and pos. correlated to the relative abundance of the genera Lentimicrobium and Methanomethylovorans. By contrast, nZVI reduced the removal of tetracycline, ciprofloxacin, and norfloxacin by AnMBR. Microbial anal. showed that nZVI dosage slightly reduced methane yield by promoting the growth of Mesotoga but reducing the proliferation of Methanomassiliicoccus to potentially disrupt the hydrogenotrophic pathway. In addition, adding nZVI reduced the ratios of protein to polysaccharide in both extracellular polymeric substances and soluble microbial products, thereby mitigating membrane fouling. In the experiment, the researchers used many compounds, for example, 4-Amino-N-(thiazol-2-yl)benzenesulfonamide (cas: 72-14-0Related Products of 72-14-0).

4-Amino-N-(thiazol-2-yl)benzenesulfonamide (cas: 72-14-0) belongs to thiazole derivatives. The higher aromaticity of thiazole is due to delocalization of a lone pair of sulfur electrons across the ring, which is evidenced by chemical shifts of ring hydrogen at δ 7.27 and 8.77 ppm (C2 and C4), indicating diamagnetic ring current. Thiazole is a versatile building block for the construction and lead generation of new drug discoveries. Numerous diazole-based compounds are in clinical use as anticancer, antileukemic, antiinflammatory, antiviral, antifungal, antirheumatic, immunomodulator, and antiparasitic agents.Related Products of 72-14-0

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica