Tag: 2933-29-1

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.2933-29-1,2-Amino-4,5,6,7-tetrahydrobenzothiazole,as a common compound, the synthetic route is as follows.

General procedure: A cold solution of NaNO2 in 5mL water was added dropwise tothe well-cooled solution of 4, 5, 6, 7-tetrahydro-1, 3-benzothiazole-2-amine (1) in 10mL HCl and stirred for 2 h at 0-5 C. Aftercompletion of the diazotization, the resulting diazonium salt solutionwas slowly added to the ice-cold solution of coupling components(3a-3e) in acetic acid and stirred for another 2 h at thesame temperature. The pH of the reaction mixture was maintainedat 5e6 by adding the required volume of the saturated solution ofsodium bicarbonate. Further, the obtained colored precipitate ofthe respective azo dyes (4a-4e) was separated by filtration, washedwith distilled water, dried and recrystallized from ethanol. Theschematic representation of the synthesis of azo dyes was presentedin Scheme 1.

The synthetic route of 2933-29-1 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Maliyappa; Keshavayya; Mallikarjuna; Murali Krishna; Shivakumara; Sandeep, Telkar; Sailaja, Krishnamurty; Nazrulla, Mohammed Azeezulla; Journal of Molecular Structure; vol. 1179; (2019); p. 630 – 641;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica

2933-29-1, 2-Amino-4,5,6,7-tetrahydrobenzothiazole is a thiazole compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

i. 4-Hydroxy-2-methyl-N-(4,5,6,7-tetrahydro-2-benzothiazolyl)- 2H-naphtho[2,1-e]-1,2-thiazine-3-carboxamide-1,1-dioxide, m. p. 255-257 C (decomp.; from ethylene chloride), from 2-methyl-4-(1-pyrrolidyl)-2H-naphtho[2,1-e]-1,2-thiazine-3-carboxylic acidchloride-1,1-dioxide and 2-amino-4,5,6,7-tetrahydrobenzothiazole.

As the paragraph descriping shows that 2933-29-1 is playing an increasingly important role.

Reference£º
Patent; Boehringer Ingelheim GmbH; US3992535; (1976); A;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica