With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.3034-57-9,2-Amino-5-bromo-4-methylthiazole,as a common compound, the synthetic route is as follows.
General procedure: A mixture of 2-amino-5-bromo-4-methylthiazole (40, 1.91 g, 0.01 mole), the appropriate 2-thioxo-quinazoline analogues (9-23, 0.01 mole), anhydrous potassium carbonate (1.5 g, 0.01 mole) in DMF (10 ml) was heated under reflux for 14 hrs. Solvent was then removed under reduced pressure and continued as mentioned under compounds 25-39 (Table 1)., 3034-57-9
3034-57-9 2-Amino-5-bromo-4-methylthiazole 12954373, athiazole compound, is more and more widely used in various.
Reference£º
Article; Al-Rashood, Sarah T.; Hassan, Ghada S.; El-Messery, Shahenda M.; Nagi, Mahmoud N.; Habib, El-Sayed E.; Al-Omary, Fatmah A.M.; El-Subbagh, Hussein I.; Bioorganic and Medicinal Chemistry Letters; vol. 24; 18; (2014); p. 4557 – 4567;,
Thiazole | C3H3NS – PubChem
Thiazole | chemical compound | Britannica