Tag: 500-600

《Phenolic profile, antioxidant, and antidiabetic potential exerted by millet grain varieties》 was published in Antioxidants in 2020. These research results belong to Ofosu, Fred Kwame; Elahi, Fazle; Daliri, Eric Banan-Mwine; Chelliah, Ramachandran; Ham, Hun Ju; Kim, Joong-Hark; Han, Sang-Ik; Hur, Jang Hyun; Oh, Deog-Hwan. Synthetic Route of C18H24N6O6S4 The article mentions the following:

This study evaluated the potential antioxidant and antidiabetic properties in vitro of four millet grain varieties cultivated in South Korea. The free fractions were tested for their total antioxidant capacity using 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS+) and 2,2′-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assays, followed by α-glucosidase, α-amylase, and advanced glycation endproducts (AGEs) formation inhibition assays. The total phenolics, flavonoids, and condensed tannins in the free fractions ranged from 107.8 to 136.4 mg ferulic acid equivalent (FAE)/100 g, 101.3 to 115.8 mg catechin equivalent (CE)/100 g, and 17.65 to 59.54 mg catechin equivalent (CE)/100 g, resp. Finger Italian millet had the highest total phenolic content (136.4 mg FAE/100 g) and flavonoid content (115.8 mg CE/100 g). Barnyard and finger Italian millet showed the highest DPPH (IC50 = 359.6μg/mL and 436.25μg/mL, resp.) and ABTS radical scavenging activity (IC50 = 362.40μg/mL and 381.65μg/mL, resp.). Similarly, finger Italian millet also exhibited significantly lower IC50 values for the percentage inhibition of α-glucosidase (18.07μg/mL) and α-amylase (10.56μg/mL) as compared with acarbose (IC50 = 59.34μg/mL and 27.73μg/mL, resp.) and AGEs formation (33.68μg/mL) as compared with aminoguanidine (AG) (52.30μg/mL). All eight phenolic compounds identified in finger Italian millet were flavonoids, with flavanols being the predominant subclass. Taken together, millet flavonoids play important roles in the prevention and management of type 2 diabetes, and hence finger Italian millet has the potential to be developed as a functional food. The results came from multiple reactions, including the reaction of ABTS Diammonium(cas: 30931-67-0Synthetic Route of C18H24N6O6S4)

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Examples of direct uses of amines and their salts are as corrosion inhibitors in boilers and in lubricating oils (morpholine), as antioxidants for rubber and roofing asphalt (diarylamines), as stabilizers for cellulose nitrate explosives (diphenylamine), as protectants against damage from gamma radiation (diarylamines), as developers in photography (aromatic diamines), as flotation agents in mining, as anticling and waterproofing agents for textiles, as fabric softeners, in paper coating, and for solubilizing herbicides.Synthetic Route of C18H24N6O6S4

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

The author of 《A convenient colorimetric bacteria detection method utilizing chitosan-coated magnetic nanoparticles》 were Le, Thao Nguyen; Tran, Tai Duc; Kim, Moon Il. And the article was published in Nanomaterials in 2020. Related Products of 30931-67-0 The author mentioned the following in the article:

An effective novel strategy to detect bacteria is promising because it may improve human health by allowing early diagnosis and timely treatment of bacterial infections. Here, we report a simple, reliable, and economical colorimetric assay using the peroxidase-like activity of chitosan-coated iron oxide magnetic nanoparticles (CS-MNPs). When CS-MNPs are incubated with a sample containing bacterial cells such as the gram-neg. Escherichia coli or the gram-pos. Staphylococcus aureus, the neg.-charged bacterial membrane interacts with pos.-charged chitosan on the surface of CS-MNPs, thus resulting in significant reduction of their peroxidase-like activity presumably by a hindrance in the accessibility of the neg. charged substrate, 2-2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) to the pos.-charged CS-MNPs. This simple colorimetric strategy allowed the rapid detection of bacterial cells down to 104 CFU mL-1 by the naked eye and 102 CFU mL-1 by spectrophotometry within 10 min. Based on the results, we anticipate that the CS-MNPs-based assay has great potential for the on-site diagnosis of bacterial infections in facility-limited or point-of-care testing (POCT) environments. In the part of experimental materials, we found many familiar compounds, such as ABTS Diammonium(cas: 30931-67-0Related Products of 30931-67-0)

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Examples of direct uses of amines and their salts are as corrosion inhibitors in boilers and in lubricating oils (morpholine), as antioxidants for rubber and roofing asphalt (diarylamines), as stabilizers for cellulose nitrate explosives (diphenylamine), as protectants against damage from gamma radiation (diarylamines), as developers in photography (aromatic diamines), as flotation agents in mining, as anticling and waterproofing agents for textiles, as fabric softeners, in paper coating, and for solubilizing herbicides.Related Products of 30931-67-0

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

In 2021,Analytical Sciences included an article by Leng, Yan; Bu, Shengjun; Li, Zhongyi; Hao, Zhuo; Ma, Chengyou; He, Xiuxia; Wan, Jiayu. COA of Formula: C18H24N6O6S4. The article was titled 《A colorimetric immunosensor based on Hemin@MI nanozyme composites, with peroxidase-like activity for point-of-care testing of pathogenic E. coli O157:H7》. The information in the text is summarized as follows:

Recently, nanozymes have become a topic of particular interest due to their high activity level, stability and biocompatibility. In this study, a visual, sensitive and selective point-of-care immunosensor was established to test the pathogen Escherichia coli O157:H7 (E. coli O157:H7). Hemin and magainin I (MI) hybrid nanocomposites (Hemin@MI) with peroxidase-mimicking activities were synthesized via a “”one-pot”” method, involving the simple mixing of an antimicrobial peptide (MI) against E. coli O157:H7 and hemin in a copper sulfate sodium phosphate saline buffer. Hemin@MI nanocomposites integrating target recognition and signal amplification were developed as signal probes for the point-ofcare colorimetric detection of pathogenic E. coli O157:H7. Hemin@MI nanocomposites exhibit excellent peroxidase activity for the chromogenic reaction of ABTS, which allows for the visual point-of-care testing of E. coli O157:H7 in the range of 102 to 108 CFU/mL, with a limit of detection of 85 CFU/mL. These data suggest this immunosensor provides accessible and portable assessments of pathogenic E. coli O157:H7 in real samples. In the experiment, the researchers used ABTS Diammonium(cas: 30931-67-0COA of Formula: C18H24N6O6S4)

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Left-handed and right-handed forms (mirror-image configurations, known as optical isomers or enantiomers) are possible when all the substituents on the central nitrogen atom are different (i.e., the nitrogen is chiral). With amines, there is extremely rapid inversion in which the two configurations are interconverted.COA of Formula: C18H24N6O6S4

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

《Phenolic compounds and antioxidant and antibacterial activities of Algerian honeys》 was written by Otmani, Amar; Amessis-Ouchemoukh, Nadia; Birinci, Ceren; Yahiaoui, Sonia; Kolayli, Sevgi; Rodriguez-Flores, Maria Shantal; Escuredo, Olga; Seijo, Maria Carmen; Ouchemoukh, Salim. Product Details of 30931-67-0 And the article was included in Food Bioscience on August 31 ,2021. The article conveys some information:

Twenty-six samples of Algerian honeys were analyzed to determine their color intensity, content of bioactive compounds using colorimetric methods and phenolic profile using a high-performance liquid chromatog.-UV (HPLC-UV) anal. The antioxidant activities of the samples were estimated using 6 methods (1,1-diphenyl-2-picrilhydrazyl and 2,2′-azinobis-3-ethylbenzothiazoline-6-sulfonic acid free radicals scavenging, reducing power, chelating ferrous activity, nitric oxide radical scavenging assay and β-carotene bleaching) and the antibacterial power was determined in vitro using agar diffusion tests and measuring minimal inhibitory concentration The color of honeys ranged from light yellow to dark amber with an intensity ranging from 350 to 1510 mAU. The highest content of total polyphenols, flavonoids, carotenoids and vitamin C and the best antioxidant activity was obtained from dark honeys. Sixteen phenolic compounds (8 phenolic acids and 8 flavonoids) were quantified. The antibacterial tests showed that Staphylococcus aureus was the most sensitive strain compared to Salmonella typhi. The results allowed establishing a quant. phenolic profile of Algerian honeys. The bioactive compounds, the antioxidant and antibacterial activities, of honey did not depend on its monofloral or polyfloral nature, but rather on the type of flowers foraged by the bees and its geog. origin. The dark color of honey is a good indicator of a higher antioxidant content and the best biol. properties.ABTS Diammonium(cas: 30931-67-0Product Details of 30931-67-0) was used in this study.

ABTS Diammonium(cas: 30931-67-0) belongs to anime. In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair. Amines are formally derivatives of ammonia (NH3), wherein one or more hydrogen atoms have been replaced by a substituent such as an alkyl or aryl group (these may respectively be called alkylamines and arylamines; amines in which both types of substituent are attached to one nitrogen atom may be called alkylarylamines).Product Details of 30931-67-0

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

《Lactobacillus bulgaricus improves antioxidant capacity of black garlic in the prevention of gestational diabetes mellitus: a randomized control trial》 was written by Si, Lihui; Lin, Ruixin; Jia, Yan; Jian, Wenwen; Yu, Qing; Wang, Min; Yang, Shuli. Application of 30931-67-0 And the article was included in Bioscience Reports on August 30 ,2019. The article conveys some information:

Lactobacillus bulgaricus may improve antioxidant capacity of black garlic in the prevention of gestational diabetes mellitus (GDM). Black garlic was prepared with or without L. bulgaricus. Volatile and polysaccharides were analyzed by using LC-MS, Fourier Transform IR (FTIR) and 13C NMR (NMR). The study design was parallel randomized controlled trial and 226 GDM patients were randomly assigned into BG (black garlic and L. bulgaricus) and CG (black garlic) groups, and allocation ratio was 1:1. The treatment duration was 40 wk. Fasting blood glucose (FBG) and 1- and 2-h blood glucose (1hBG and 2hBG) after oral glucose tolerance test (OGTT) were detected. Antioxidant function of black garlic was determined by measuring plasma malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GSH-PX) and total antioxidant capacity (T-AOC) in GDM patients. The comparison between two groups was made using two independent samples t test. The intake of nutrients was similar between two groups (P>0.05). L. bulgaricus promoted the transformation of the glucopyranoside to glucofuranoside. L. bulgaricus increased the abilities of black garlic for scavenging hydroxyl radicals, 2,2′-azino-bis (3-ethylbenzenthiazoline-6-sulfonic) acid (ABTS) and DPPH free radicals. L. bulgaricus reduced the levels of FBG, 1hBG and 2hBG, and incidence of perinatal complications (P<0.01). Plasma MDA level in the BG group was lower than in the CG group, whereas the levels of SOD, GSH-PX and T-AOC in the BG group were higher than in the CG group (P<0.01). L. bulgaricus improves antioxidant capacity of black garlic in the prevention of GDM. In the experimental materials used by the author, we found ABTS Diammonium(cas: 30931-67-0Application of 30931-67-0)

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Large quantities of aliphatic amines are made synthetically. The most widely used industrial method is the reaction of alcohols with ammonia at a high temperature, catalyzed by metals or metal oxide catalysts (e.g., nickel or copper). Mixtures of primary, secondary, and tertiary amines are thereby produced.Application of 30931-67-0

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Quality Control of ABTS DiammoniumOn October 15, 2019 ,《Reactivity of chromophoric dissolved organic matter (CDOM) to sulfate radicals: Reaction kinetics and structural transformation》 was published in Water Research. The article was written by Zhang, Suona; Rouge, Valentin; Gutierrez, Leonardo; Croue, Jean-Philippe. The article contains the following contents:

SO4·- would selectively react with electron rich moieties in DOM, known as chromophoric DOM (CDOM), due to its light absorbing property. In this study, the reactivity and typical structural transformation of CDOM with SO·-4 was investigated. Four well characterized hydrophobic DOM fractions extracted from different surface water sources were selected as model CDOM. SO4·- was produced through the activation of peroxymonosulfate (PMS) by Co(II) ions at pH 8 in borate buffer. The reactivity of CDOM changed with time where fast and slow reacting CDOMs (i.e., CDOMfast and CDOMslow) were clearly distinguished. A second-order rate constant of CDOMfast with SO·-4 was calculated by plotting UVA254 decrease vs. PMS exposure; where a Rct value (i.e., ratio of sulfate radical exposure to PMS exposure) was calculated using pCBA as a probe compound The transformation of CDOM was studied through the anal. of the changes in UVA254, electron donating capacity, fluorescence intensity, and total organic carbon. A transformation pathway leading to a significant carbon removal was proposed. This new knowledge on the kinetics and transformation of CDOM would ultimately assist in the development and operation of SO·-4-based water treatment processes. The results came from multiple reactions, including the reaction of ABTS Diammonium(cas: 30931-67-0Quality Control of ABTS Diammonium)

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Left-handed and right-handed forms (mirror-image configurations, known as optical isomers or enantiomers) are possible when all the substituents on the central nitrogen atom are different (i.e., the nitrogen is chiral). With amines, there is extremely rapid inversion in which the two configurations are interconverted.Quality Control of ABTS Diammonium

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

In 2019,Molecules included an article by Zlotek, Urszula; Szymanowska, Urszula; Pecio, Lukasz; Kozachok, Solomiia; Jakubczyk, Anna. Related Products of 30931-67-0. The article was titled 《Antioxidative and potentially anti-inflammatory activity of phenolics from lovage Leaves Levisticum officinale koch elicited with jasmonic acid and yeast extract》. The information in the text is summarized as follows:

The effect of elicitation with jasmonic acids (JA) and yeast extract (YE) on the production of phenolic compounds as well as the antioxidant and anti-inflammatory properties of phenolic extracts of lovage was evaluated. The anal. of phenolic compounds carried out with the UPLCMS technique indicated that rutin was the dominant flavonoid, while 5-caffeoylquinic acid was the main component in the phenolic acid fraction in the lovage leaves. The application of 10μM JA increased the content of most of the identified phenolic compounds The highest antioxidant activities estimated as free radical scavenging activity against ABTS (2,2′-azino-bis(3- ethylbenzothiazoline-6-sulfonic acid)) and reducing power were determined for the sample elicited with 10μM JA, while this value determined as iron chelating ability was the highest for the 0.1% YE-elicited lovage. The 0.1% and 1% YE elicitation also caused significant elevation of the lipoxygenase (LOX) inhibition ability, while all the concentrations of the tested elicitors significantly improved the ability to inhibit cyclooxygenase 2 (COX2) (best results were detected for the 10μM JA and 0.1% YE2 sample). Thus, 0.1% yeast extract and 10μM jasmonic acid proved to be most effective in elevation of the biol. activity of lovage. In the experiment, the researchers used ABTS Diammonium(cas: 30931-67-0Related Products of 30931-67-0)

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Halogenation, in which one or more hydrogen atoms of an amine is replaced by a halogen atom, occurs with chlorine, bromine, and iodine, as well as with some other reagents, notably hypochlorous acid (HClO). With primary amines the reaction proceeds in two stages, producing N-chloro- and N,N-dichloro-amines, RNHCl and RNCl2, respectively. With tertiary amines, an alkyl group may be displaced by a halogen.Related Products of 30931-67-0

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

In 2019,Molecules included an article by Avato, Pinarosa; Argentieri, Maria Pia. Computed Properties of C18H24N6O6S4. The article was titled 《Quality assessment of commercial spagyric tinctures of Harpagophytum procumbens and their antioxidant properties》. The information in the text is summarized as follows:

Preparations from the dried tubers of Harpagophytum procumbens (Burch.) DC ex Meisn, commonly known as devil’s claw, are mainly used in modern medicine to relieve joint pain and inflammation in patients suffering from rheumatic and arthritic disorders. This paper describes for the first time the chem. profile of a com. spagyric tincture (named 019) prepared from the roots of the plant. For comparison purposes, a com. not-spagyric devil’s claw tincture (NST) was also analyzed. Chem. investigation of the content of specialized metabolites in the three samples indicated that harpagoside was the main compound, followed by the two isomers acteoside and isoacteoside. Compositional consistence over time was obtained by the chem. fingerprinting of another spagyric tincture (named 014) from the same producer that was already expired according to the recommendation on the label of the product. The two spagyric preparations did not show significant compositional differences as revealed by HPLC and MS analyses, except for a decrease in harpagide content in the expired 014 tincture. Moreover, their antioxidant capacities as assessed by 2,2′-di-phenyl-1-picrylhydrazyl (DPPH) and 2.2′-azin-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) methods resulted in very similar IC50 values. The expired 014 tincture showed instead a lower IC50 value compared to the 019 and NST tinctures with the ferric reducing antioxidant potential (FRAP) assay, indicating a higher ferric-reducing antioxidant ability. Overall, these results indicated that the two preparations could generally maintain good stability and biol. activity at least for the four years from the production to the expiration date. In the experiment, the researchers used many compounds, for example, ABTS Diammonium(cas: 30931-67-0Computed Properties of C18H24N6O6S4)

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Nitrous acid converts secondary amines (aliphatic or aromatic) to N-nitroso compounds (nitrosamines): R2NH + HNO2 → R2N―NO. Some nitrosamines are potent cancer-inducing substances, and their possible formation is a serious consideration when nitrites, which are salts of nitrous acid, are present in foods or pharmaceutical preparations. Tertiary amines give rise to nitrosamines more slowly; an alkyl group is eliminated as an aldehyde or ketone, along with nitrous oxide, N2O.Computed Properties of C18H24N6O6S4

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

《Revealing the active site of gold nanoparticles for the peroxidase-like activity: the determination of surface accessibility》 was published in Catalysts in 2019. These research results belong to Liu, Ching-Ping; Chen, Kuan-Chung; Su, Ching-Feng; Yu, Po-Yen; Lee, Po-Wei. Related Products of 30931-67-0 The article mentions the following:

Despite the fact that the enzyme-like activities of nanozymes (i.e., nanomaterial-based artificial enzymes) are highly associated with their surface properties, little is known about the catalytic active sites. Here, we used the sulfide ion (S2-)-induced inhibition of peroxidase-like activity to explore active sites of gold nanoparticles (AuNPs). The inhibition mechanism was based on the interaction with Au(I) to form Au2S, implying that the Au(I) might be the active site of AuNPs for the peroxidase-like activity. XPS anal. showed that the content of Au(I) on the surface of AuNPs significantly decreased after the addition of S2-, which might be contributed to the more covalent Au-S bond in the formation of Au2S. Importantly, the variations of Au(I) with and without the addition of S2- for di erent surface-capped AuNPs were in good accordance with their corresponding peroxidase-like activities. These results confirmed that the accessible Au(I) on the surface was the main requisite for the peroxidase-like activity of AuNPs for the first time. In addition, the use of S2- could assist to determine available active sites for di erent surface modified AuNPs. This work not only provides a new method to evaluate the surface accessibility of colloidal AuNPs but also gains insight on the design of efficient AuNP-based peroxidase mimics. After reading the article, we found that the author used ABTS Diammonium(cas: 30931-67-0Related Products of 30931-67-0)

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Primary amines having a tertiary alkyl group (R3CNH2) are difficult to prepare with most methods but are made industrially by the Ritter reaction. In this method a tertiary alcohol reacts with hydrogen cyanide (HCN) in the presence of a concentrated strong acid; a formamide, RNH―CHO, is formed first, which then undergoes hydrolysis.Related Products of 30931-67-0

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

《Carbohydrates profile, polyphenols content and antioxidative properties of beer worts produced with different dark malts varieties or roasted barley grains》 was published in Molecules in 2020. These research results belong to Gasior, Justyna; Kawa-Rygielska, Joanna; Kucharska, Alicja Z.. Safety of ABTS Diammonium The article mentions the following:

The aim of this study was to assess the possibility of shaping properties of beers at the stage of brewing wort production with the use of various types of special malts (chocolate pale, chocolate dark, wheat chocolate, brown barley) and roasted barley grains. The carbohydrate profile, polyphenols content, antioxidant capacity, 5-hydroxymethylfurfural content, and the browning index level were analyzed. Statistical anal. showed significant differences in the values of the examined features between the samples. The sugars whose content was most affected by the addition of special malts were maltose and dextrins. The polyphenol content in worts with 10% of additive was 176.02-397.03 mg GAE/L, ferric reducing antioxidant power (FRAP) 1.32-2.07 mmol TE/L, and capacity to reduction radical generated from 2,2′-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS•+) 1.46-2.70 mmol TE/L. Wort with 40% dark malt showed the highest content of polyphenolic compounds and antioxidant activity (FRAP and ABTS•+). The HMF content and the browning index value were higher for wort with the addition of darker-colored malts (EBC) and increased with increasing dark malt dose. The experimental process involved the reaction of ABTS Diammonium(cas: 30931-67-0Safety of ABTS Diammonium)

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Aniline, ethanolamines, and several other amines are major industrial commodities used in making rubber, dyes, pharmaceuticals, and synthetic resins and fibres and for a host of other applications. Most of the numerous methods for the preparation of amines may be broadly divided into two groups: (1) chemical reduction (replacement of oxygen with hydrogen atoms in the molecule) of members of several other classes of organic nitrogen compounds and (2) reactions of ammonia or amines with organic compounds.Safety of ABTS Diammonium

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica