500-600归档 - Page 4 of 13 - Heterocyclic Building Blocks-Thiazole

Wang, Guangning’s team published research in Pharmacognosy Magazine in 2020 | CAS: 30931-67-0

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Halogenation, in which one or more hydrogen atoms of an amine is replaced by a halogen atom, occurs with chlorine, bromine, and iodine, as well as with some other reagents, notably hypochlorous acid (HClO). With primary amines the reaction proceeds in two stages, producing N-chloro- and N,N-dichloro-amines, RNHCl and RNCl2, respectively. With tertiary amines, an alkyl group may be displaced by a halogen.COA of Formula: C18H24N6O6S4

The author of 《Comparison of the content of flavonoids, total phenols, and carotenoids and antioxidant activity in Guang Citri reticulatae pericarpium during the aging time》 were Wang, Guangning; Chen, Shuwen; Gu, Guangshan; Qiu, Jieqing; Chen, Yuanling; Jia, Zhen; Tang, Hongmei. And the article was published in Pharmacognosy Magazine in 2020. COA of Formula: C18H24N6O6S4 The author mentioned the following in the article:

GCRP must be aged by stored for several years before it can be used as medicine. In the aging process, content of composition, antioxidant activity, and color of GCRP have changed. The objective of this study was to compare the content of flavonoids, total phenols, and carotenoids and antioxidant activity in GCRP during the aging time and analyze the correlations of the data. 40 Batches of GCRP in different aging years were used for qual. and quant. anal. of flavonoids, total phenols, and carotenoids by ultra-high-performance liquid chromatog. (HPLC)-mass spectrometry, HPLC-diode array detector, and UV methods. 2,2′-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt and 1,1-diphenyl-2-trinitrophenylhydrazine methods were used to compare the antioxidant activity of GCRP. Colorimetric anal. method was used to detect the external color of GCRP. SPSS software was used to analyze the correlation of all data. With the increase of aging year, the content of three flavonoids and total phenols increased and the content of carotenoids decreased. The results showed that the antioxidant activity of ether extract increased significantly with aging year and methanol extract decreased. The correlation results showed that the content of carotenoids was more closely related to chromaticity values and antioxidant activity. The result provides more objective and detailed information to analyze the quality of GCRP during the aging time. After reading the article, we found that the author used ABTS Diammonium(cas: 30931-67-0COA of Formula: C18H24N6O6S4)

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Stanciauskaite, Monika’s team published research in Pharmaceuticals in 2021 | CAS: 30931-67-0

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Amines characteristically form salts with acids; a hydrogen ion, H+, adds to the nitrogen. With the strong mineral acids (e.g., H2SO4, HNO3, and HCl), the reaction is vigorous. Salt formation is instantly reversed by strong bases such as NaOH. Neutral electrophiles (compounds attracted to regions of negative charge) also react with amines; alkyl halides (R′X) and analogous alkylating agents are important examples of electrophilic reagents.Quality Control of ABTS Diammonium

In 2021,Pharmaceuticals included an article by Stanciauskaite, Monika; Marksa, Mindaugas; Babickaite, Lina; Majiene, Daiva; Ramanauskiene, Kristina. Quality Control of ABTS Diammonium. The article was titled 《Comparison of Ethanolic and Aqueous Populus balsamifera L. Bud Extracts by Different Extraction Methods: Chemical Composition, Antioxidant and Antibacterial Activities》. The information in the text is summarized as follows:

The balsam poplar (Populus balsamifera L.) buds that grow in Lithuania are a polyphenol-rich plant material with a chem. composition close to that of propolis. In order to potentially adapt the extracts of this plant’s raw material for therapeutic purposes, it is important to carry out detailed studies on the chem. composition and biol. activity of balsam poplar buds. An important step is to evaluate the yield of polyphenols by different extraction methods and using different solvents. According to our research, extracts of balsam poplar buds collected in Lithuania are dominated by p-coumaric (496.9-13,291.2μg/g), cinnamic acid (32.9-11,788.5μg/g), pinobanksin (34.9-1775.5μg/g) and salicin (215.3-1190.7μg/g). The antioxidant activity of poplar buds was evaluated by the ABTS (2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)), DPPH (2,2-diphenyl-1-picrylhydrazyl) and FRAP (ferric-reducing antioxidant power) methods, all extracts showed antioxidant activity and the obtained results correlated with the obtained amounts of total phenolic compounds in the extracts (ABTS r = 0.974; DPPH r = 0.986; FRAP r = 0.955, p <0.01). Studies of antimicrobial activity have shown that ethanolic extracts have an antimicrobal activity effect against Staphylococcus aureus, Enterococcus faecalis and Escherichia coli. The extracts showed a better antimicrobal activity against gram-pos. bacteria. In the part of experimental materials, we found many familiar compounds, such as ABTS Diammonium(cas: 30931-67-0Quality Control of ABTS Diammonium)

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Li, Wei’s team published research in Polymers (Basel, Switzerland) in 2019 | CAS: 30931-67-0

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Amines have a free lone pair with which they can coordinate to metal centers. Amine–metal bonds are weaker because amines are incapable of backbonding, but they are still important for sensing applications.While stronger than hydrogen bonds, amine–metal bonds are still weaker than both covalent and ionic bonds.Safety of ABTS Diammonium

The author of 《Influence of nano titanium dioxide and clove oil on chitosan-starch film characteristics》 were Li, Wei; Zheng, Kewang; Chen, Hujian; Feng, Shirong; Wang, Wei; Qin, Caiqin. And the article was published in Polymers (Basel, Switzerland) in 2019. Safety of ABTS Diammonium The author mentioned the following in the article:

The combined effects of nano titanium dioxide (TiO2-N) and clove oil (CO) on the physico-chem., biol. and structural properties of chitosan (CH)/starch (ST) films were investigated by using a solvent casting method. Results indicated that the incorporation of TiO2-N could improve the compactness of the film, increase the tensile strength (TS) and antioxidant activity, and decrease the water vapor permeability (WVP). As may be expected, the incorporation of CO into the film matrix decreased TS but increased the hydrophobicity as well as water vapor barrier antimicrobial and antioxidant properties. Fourier-transform IR spectroscopy (FTIR) data supported intermol. interactions between TiO2-N, CO and the film matrix. Use of a scanning electron microscope (SEM) showed that TiO2-N and CO were well dispersed and emulsified in the film network. Thermogravimetric (TG) and derivative thermogravimetric (DTG) curves demonstrated that TiO2-N and CO were well embedded in the film matrix, hence this blend film system could provide new formulation options for food packaging materials in the future. In the experiment, the researchers used ABTS Diammonium(cas: 30931-67-0Safety of ABTS Diammonium)

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Wu, Dingsheng’s team published research in Bioresource Technology in 2022 | CAS: 30931-67-0

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Nitrous acid converts secondary amines (aliphatic or aromatic) to N-nitroso compounds (nitrosamines): R2NH + HNO2 → R2N―NO. Some nitrosamines are potent cancer-inducing substances, and their possible formation is a serious consideration when nitrites, which are salts of nitrous acid, are present in foods or pharmaceutical preparations. Tertiary amines give rise to nitrosamines more slowly; an alkyl group is eliminated as an aldehyde or ketone, along with nitrous oxide, N2O.Electric Literature of C18H24N6O6S4

Wu, Dingsheng; Lv, Pengfei; Feng, Quan; Jiang, Yu; Yang, Hanrui; Alfred, Mensah; Wei, Qufu published an article in Bioresource Technology. The title of the article was 《Biomass-derived nanocellulose aerogel enable highly efficient immobilization of laccase for the degradation of organic pollutants》.Electric Literature of C18H24N6O6S4 The author mentioned the following in the article:

Laccase is a promising biocatalyst for pollutant degradation and water purification However, laccase can only improve the stability of enzyme activity and achieve its significant catalytic effect after effective immobilization. Herein, we report a general strategy to integrate nanocellulose aerogel and laccase for high-efficiency degradation of organic pollutants. Biomass-derived functional bacterial cellulose (BC) aerogel with a nanonetwork structure and high porosity was prepared by biosynthesis, solvent replacement, and atom transfer radical polymerization (ATRP) procedures. Subsequently, a biocatalyst platform was fabricated by “”coupling”” ATRP-modified BC aerogel with abundant active sites with laccase through ion coordination. The results demonstrated the biocatalyst platform not only has good biol. affinity, but also has high enzyme load and structural stability. Meanwhile, the degradation rates of reactive red X-3B and 2, 4-dichlorophenol reached 94.5% and 85.2% within 4 h, resp. The strategy disclosed herein could provide a practical method for the degradation of organic pollutants. The experimental process involved the reaction of ABTS Diammonium(cas: 30931-67-0Electric Literature of C18H24N6O6S4)

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Akhil’s team published research in Industrial Crops and Products in 2020 | CAS: 30931-67-0

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Many important products require amines as part of their syntheses. Methylamine is utilized in the production of the analgesic meperidine (trade name Demerol) and the photographic developer Metol (trademark), and dimethylamine is used in the synthesis of the antihistamine diphenhydramine (trade name Benadryl), the solvent dimethylformamide (DMF), and the rocket propellant 1,1-dimethylhydrazine. The synthesis of the insect repellent N,N-diethyl-m-toluamide (DEET) incorporates diethylamine while that of the synthetic fibre Kevlar requires aromatic amines.Application of 30931-67-0

《Comparative evaluation of laccase mediated oxidized and unoxidized lignin of sugarcane bagasse for the synthesis of lignin-based formaldehyde resin》 was written by Akhil; Devendra, Leena P.; Sukumaran, Rajeev K.. Application of 30931-67-0 And the article was included in Industrial Crops and Products on August 31 ,2020. The article conveys some information:

Pretreatment using dilute acid is one of the strategies employed in a lignocellulosic biorefinery. The current study deals with the isolation, characterization, and oxidation of lignin from the enzymic residue of acid pre-treated sugarcane bagasse. The study also focused on evaluating the reactivity of Laccase mediated oxidized lignin with the non-oxidized one for the preparation of lignin-based formaldehyde (LF) resin. In the current study, 100% phenolic lignin was utilized for the synthesis of LF resin. Three different approaches (Alk. hydrolysis, mild acidolysis & organosolv) have been employed to evaluate the effect of isolation method on the physicochem. properties of lignin. The isolation method had a bearing on the properties of lignin and its reactivity towards formaldehyde for the synthesis of LF resin. Alkali and organosolv lignin were found as promising candidates for the preparation of LF resin. Oxidized lignin exhibited better reactivity than the non-oxidized one. The experimental part of the paper was very detailed, including the reaction process of ABTS Diammonium(cas: 30931-67-0Application of 30931-67-0)

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Tang, Yue’s team published research in Analytica Chimica Acta in 2020 | CAS: 30931-67-0

ABTS Diammonium(cas: 30931-67-0) belongs to anime.Typically the presence of an amine functional group is deduced by a combination of techniques, including mass spectrometry as well as NMR and IR spectroscopies. 1H NMR signals for amines disappear upon treatment of the sample with D2O. In their infrared spectrum primary amines exhibit two N-H bands, whereas secondary amines exhibit only one.Synthetic Route of C18H24N6O6S4

《A facile colorimetric sensor for ultrasensitive and selective detection of Lead(II) in environmental and biological samples based on intrinsic peroxidase-mimic activity of WS2 nanosheets》 was written by Tang, Yue; Hu, Yang; Yang, Yuxia; Liu, Bangyan; Wu, Yuangen. Synthetic Route of C18H24N6O6S4 And the article was included in Analytica Chimica Acta on April 15 ,2020. The article conveys some information:

Two-dimensional layered WS2 nanosheets with rich active edge exhibit intrinsic peroxidase-mimic activity, which make them an ideal material for sensor design. However, there is still lack of research on the catalysis and regulation mechanisms of the layered WS2 nanosheets as well as their application in the detection of hazardous substances. Herein, the regulatory effect of Pb(II) on the peroxidase-mimic activity of the layered WS2 nanosheets was firstly investigated, which enable us to construct a novel and facile colorimetric sensor for ultrasensitive and selective detection of Pb(II). To improve the performance of colorimetric sensor, some important parameters like buffer conditions, substrates and temperature have been investigated. Under the optimal conditions, the catalytic kinetics of layered WS2 nanosheets were extensively investigated. The peroxidase-mimic catalytic reaction was proved to be the “”ping pong”” mechanism, and the regulatory effect of Pb(II) on layered WS2 nanosheets was agreed with noncompetitive inhibition. The absorbance variation of colorimetric sensor is proportionally related to the concentration of heavy metals, which enable us to easily distinguish whether Pb(II) exceeds the permissible level in less than 20 min even by the naked eyes. The limit of detection (LOD) and the limit of quantification (LOQ) of the proposed colorimetric sensor for Pb(II) were determined as low as 4μg L-1 and 13.3μg L-1, and displays excellent selectivity against other competitive metal ions. Moreover, the further studies also validate the applicability of colorimetric sensor in several actual samples, indicating that our strategy may has prospective applications for Pb(II) detection in environment and biol. samples.ABTS Diammonium(cas: 30931-67-0Synthetic Route of C18H24N6O6S4) was used in this study.

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Yan, Bingsong’s team published research in Microchimica Acta in 2021 | CAS: 30931-67-0

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Reduction of nitro compounds, RNO2, by hydrogen or other reducing agents produces primary amines cleanly (i.e., without a mixture of products), but the method is mostly used for aromatic amines because of the limited availability of aliphatic nitro compounds. Reduction of nitriles and oximes (R2C=NOH) also yields primary amines.Quality Control of ABTS Diammonium

Quality Control of ABTS DiammoniumOn May 31, 2021, Yan, Bingsong; Liu, Wendong; Duan, Guangbin; Ni, Pengjuan; Jiang, Yuanyuan; Zhang, Chenghui; Wang, Bo; Lu, Yizhong; Chen, Chuanxia published an article in Microchimica Acta. The article was 《Colorimetric detection of acetylcholinesterase and its inhibitor based on thiol-regulated oxidase-like activity of 2D palladium square nanoplates on reduced graphene oxide》. The article mentions the following:

A convenient and sensitive colorimetric assay for acetylcholinesterase (AChE) and its inhibitor has been designed based on the oxidase-like activity of {100}-faceted Pd square nanoplates which are grown in situ on reduced graphene oxide (PdSP@rGO). PdSP@rGO can effectively catalyze the oxidation of colorless 3,3′,5,5′-tetramethylbenzidine (TMB) without the assistance of H2O2 to generate blue oxidized TMB (oxTMB) with a characteristic absorption peak at 652 nm. In the presence of AChE, acetylthiocholine (ATCh), a typical AChE substrate, is hydrolyzed to thiocholine (TCh). The generated TCh can effectively inhibit the PdSP@rGO-triggered chromogenic reaction of TMB via cheating with Pd, resulting in color fading and decrease in absorbance. Thus, a sensitive probe for AChE activity is constructed with a working range of 0.25-5 mU mL-1 and a limit of detection (LOD) of 0.0625 mU mL-1. Furthermore, because of the inhibition effect of tacrine on AChE, tacrine is also detected through the colorimetric AChE assay system within the concentrations range 0.025-0.4μM with a LOD of 0.00229μM. Hence, a rapid and facile colorimetric procedure to sensitively detect AChE and its inhibitor can be anticipated through modulating the oxidase-like activity of [email protected] Diammonium(cas: 30931-67-0Quality Control of ABTS Diammonium) was used in this study.

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Stenholm, Aake’s team published research in Environmental Technology in 2019 | CAS: 30931-67-0

ABTS Diammonium(cas: 30931-67-0) belongs to anime. To avoid the problem of multiple alkylation, methods have been devised for “blocking” substitution so that only one alkyl group is introduced. The Gabriel synthesis is one such method; it utilizes phthalimide, C6H4(CO)2NH, whose one acidic hydrogen atom has been removed upon the addition of a base such as KOH to form a salt.Formula: C18H24N6O6S4

The author of 《Removal of diclofenac from a non-sterile aqueous system using Trametes versicolor with an emphasis on adsorption and biodegradation mechanisms》 were Stenholm, Aake; Hedeland, Mikael; Arvidsson, Torbjoern; Pettersson, Curt E.. And the article was published in Environmental Technology in 2019. Formula: C18H24N6O6S4 The author mentioned the following in the article:

This paper describes the search for procedures through which the xenobiotic pollutant diclofenac can be removed from non-sterile aquatic systems. Specifically, adsorption to solid supports (carriers) in combination with biodegradation by non-immobilized and immobilized white rot fungus Trametes versicolor were investigated. Batch experiments using polyurethane foam (PUF)-carriers resulted in 99.9% diclofenac removal after 4 h, with monolayer adsorption of diclofenac to carrier and glass surfaces accounting for most of the diclofenac decrease. Enzymic reactions contributed less, accounting for approx. < 0.5% of this decrease. In bioreactor experiments using PUF-carriers, an initial 100% removal was achieved with biodegradation contributing approx. 7%. In batch experiments that utilized polyethylene-carriers with negligible immobilization of Trametes versicolor, a 98% total diclofenac removal was achieved after one week, with a biodegradation contribution of approx. 14%. Five novel enzyme-catalyzed biodegradation products were tentatively identified in the batch-wise and bioreactor experiments using full scan ultra-high-performance liquid chromatog.-quadrupole/time of flight mass spectrometry. Both reduction and oxidation products were found, with the contents estimated to be at μg L-1 concentration levels. In the experiment, the researchers used many compounds, for example, ABTS Diammonium(cas: 30931-67-0Formula: C18H24N6O6S4)

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Wang, Guangning’s team published research in Pharmacognosy Magazine in 2020 | CAS: 30931-67-0

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Stanciauskaite, Monika’s team published research in Pharmaceuticals in 2021 | CAS: 30931-67-0

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica