Tag: 500-600

《One-step photostructuring of multiple hydrogel arrays for compartmentalized enzyme reactions in microfluidic devices》 was published in Reaction Chemistry & Engineering in 2019. These research results belong to Obst, Franziska; Simon, David; Mehner, Philipp J.; Neubauer, Jens W.; Beck, Anthony; Stroyuk, Oleksandr; Richter, Andreas; Voit, Brigitte; Appelhans, Dietmar. Product Details of 30931-67-0 The article mentions the following:

We present a technique for the simultaneous photostructuring of hydrogels on the μm scale with different compositions on one substrate. The existing methods (e.g. spin-coating of the hydrogel precursor and application of simple molds or spacers) have less potential to integrate spatially separated functional hydrogel dots as needed for the fabrication of complex polydimethylsiloxane (PDMS) on-glass microfluidic chips. Here, we report a method for the fast production of precisely placed hydrogel structures with adjustable height (= 80μm) and width (= 500μm) on glass substrates utilizing black polyoxymethylene molds. The integration of several chambers for different hydrogel precursor solutions in one mold allows the simultaneous photopolymerization of hydrogels with different compositions To visualize the difference in composition of the hydrogel dots and to demonstrate the precision in structuring, various quantum dots were added to the hydrogel precursor solutions and phys. entrapped during the photopolymerization To show the high potential of our photostructuring method, a microfluidic double-chamber reactor was designed and the variability in the performance of tri-enzymic cascade reactions with optionally spatially separated or non-separated enzymes β-galactosidase, glucose oxidase, and horseradish peroxidase was visualized.ABTS Diammonium(cas: 30931-67-0Product Details of 30931-67-0) was used in this study.

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Hydrogen peroxide (H2O2) and peroxy acids generally add an oxygen atom to the nitrogen of amines. With primary amines, this step is normally followed by further oxidation, leading to nitroso compounds, RNO, or nitro compounds, RNO2. Secondary amines are converted to hydroxylamines, R2NOH, and tertiary amines to amine oxides, R3NO.Product Details of 30931-67-0

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Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Recommanded Product: 30931-67-0On November 30, 2020 ,《Eosin Y as a high-efficient photooxidase mimic for colorimetric detection of sodium azide》 appeared in Analytical and Bioanalytical Chemistry. The author of the article were Wang, Junren; Yu, Haili; He, Yi. The article conveys some information:

Abstract: The reported fluorescent dye-based artificial light-responsive oxidase mimics are suffering from their low catalytic efficiency. To overcome the limitation, we report the photooxidase-mimicking activity of Eosin Y which can catalyze the oxidation of various chromogenic substrates such as 3,3′,5,5′-tetramethylbenzydine (TMB), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS), 3,3′-diaminobenzidine (DAB), and o-phenylenediamine (OPD) by dissolved oxygen. The photooxidase-like activity of Eosin Y is highly efficient for TMB substrate, and its catalytic efficiency is higher than that of the reported fluorescein (130 fold) and 9-mesityl-10-methylacridinium ion (7.7-fold) mimetic photooxidase. Moreover, the photosensitized Eosin Y-TMB chromogenic system is utilized for colorimetric detection of highly toxic and explosive sodium azide (NaN3) in a linear range from 5 to 500 μM with a limit of detection of 3.5 μM. The resulting colorimetric assay is selective and applied to determine NaN3 in real lake water samples. The experimental part of the paper was very detailed, including the reaction process of ABTS Diammonium(cas: 30931-67-0Recommanded Product: 30931-67-0)

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Amine, any member of a family of nitrogen-containing organic compounds that is derived, either in principle or in practice, from ammonia (NH3). Naturally occurring amines include the alkaloids, which are present in certain plants; the catecholamine neurotransmitters (i.e., dopamine, epinephrine, and norepinephrine); and a local chemical mediator, histamine, that occurs in most animal tissues.Recommanded Product: 30931-67-0

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Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

《Programmable and Reversible Regulation of Catalytic Hemin@MOFs Activities with DNA Structures》 was written by Liu, Shuo; Yang, Mingjie; Guo, Weiwei. Electric Literature of C18H24N6O6S4 And the article was included in Chemical Research in Chinese Universities on April 30 ,2020. The article conveys some information:

Abstract: Metal-organic frameworks(MOFs)-based nanozyme plays an important role in biosensing, therapy and catalysis. In this study, the effects of single-stranded DNA(ssDNA) with programmable sequences and its complementary DNA(TDNA) on the intrinsic peroxidase-like activity of hemin loaded MOFs(UiO-66-2), denoted as hemin@UiO-66-NH2, were investigated. The hemin@UiO-66-2 exhibited improved catalytic activity compared with free hemin. However, the catalytic activity is inhibited in the presence of ssDNA, as ssDNA can be adsorbed by MOFs and therefore protected the active sites from contact with substrates. Upon the addition of the TDNA, double-stranded DNA(dsDNA) was formed and detached from the MOFs, resulting in the recovery of catalytic activity. Sequentially adding ssDNA or its complementary DNA strands can achieve the reversible regulation of the catalytic activity of MOFs nanozymes. Moreover, the DNA hybridization-based regulation was further applied to a cascaded catalytic system composed of the nanozyme, hemin@UiO-66-NH2, and glucose oxidase. These nanozyme based programmable and reversibly regulated catalytic systems may have potential applications in future smart biosensing and catalysis systems. In addition to this study using ABTS Diammonium, there are many other studies that have used ABTS Diammonium(cas: 30931-67-0Electric Literature of C18H24N6O6S4) was used in this study.

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Amines characteristically form salts with acids; a hydrogen ion, H+, adds to the nitrogen. With the strong mineral acids (e.g., H2SO4, HNO3, and HCl), the reaction is vigorous. Salt formation is instantly reversed by strong bases such as NaOH. Neutral electrophiles (compounds attracted to regions of negative charge) also react with amines; alkyl halides (R′X) and analogous alkylating agents are important examples of electrophilic reagents.Electric Literature of C18H24N6O6S4

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Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

《Methionine augments antioxidant activity of rice protein during gastrointestinal digestion》 was published in International Journal of Molecular Sciences in 2019. These research results belong to Li, Hui; Wang, Zhengxuan; Liang, Mingcai; Cai, Liang; Yang, Lin. Computed Properties of C18H24N6O6S4 The article mentions the following:

To elucidate the influence of methionine, which is an essential sulfur-containing amino acid, on the antioxidant activity of rice protein (RP), methionine was added to RP (RM). The addition of methionine to RM0.5, RM1.0, RM1.5, RM2.0, and RM2.5 was 0.5-, 1.0-, 1.5-, 2.0-, and 2.5-fold of methionine of RP, resp. Using the in vitro digestive system, the antioxidant capacities of scavenging free radicals (superoxide; nitric oxide; 2,2′-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt, ABTS), chelating metal (iron), and reducing power were investigated in the hydrolyzates of RP and RMs. Upon pepsin-pancreatin digestion, the weakest antioxidant capacity was produced by RP. With the addition of methionine, RMs exhibited more excellent responses to free radical scavenging activities and reducing power than RP, whereas RMs did not produce the marked enhancements in iron chelating activity as compared to RP. The present study demonstrated that RMs differently exerted the free radical scavenging activities that emerged in the protein hydrolyzates, in which the strongest scavenging capacities for ABTS, superoxide, and nitric oxide were RM1.5, RM2.0, and RM2.5, resp. Results suggested that the availability of methionine is a critical factor to augment antioxidant ability of RP in the in vitro gastrointestinal tract. In the part of experimental materials, we found many familiar compounds, such as ABTS Diammonium(cas: 30931-67-0Computed Properties of C18H24N6O6S4)

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Reduction of nitro compounds, RNO2, by hydrogen or other reducing agents produces primary amines cleanly (i.e., without a mixture of products), but the method is mostly used for aromatic amines because of the limited availability of aliphatic nitro compounds. Reduction of nitriles and oximes (R2C=NOH) also yields primary amines.Computed Properties of C18H24N6O6S4

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Xia, Huan; Zhong, Xue; Li, Zhixian; Jiang, Yanbin published an article in Journal of Colloid and Interface Science. The title of the article was 《Palladium-mediated hybrid biocatalysts with enhanced enzymatic catalytic performance via allosteric effects》.Synthetic Route of C18H24N6O6S4 The author mentioned the following in the article:

High activity and stability of immobilized enzymes have been constant pursuits and critical challenges for decades. Herein, Cytochrome c (peroxidase, Cyt c) and its corresponding enzyme mimic (Pd nanoparticles) were combined and successfully embedded into a zeolitic imidazolate framework-8 (ZIF-8) to enhance the enzymic catalytic performance using a biomimetic mineralization approach. Owing to allosteric effects of Cyt c-Pd complexes, the as-synthesized Cyt c-Pd@ZIF-8 composites exhibit an increased turnover number (approx. 2.4-fold for kcat) and an enhanced catalytic efficiency (approx. 2.3-fold for kcat/KM) compared to free Cyt c; also the shielding effect of ZIF-8 endows enzyme with improved resistance against harsh conditions (e.g. high temperatures and organic solvents). The strategy, which integrates enzyme with its enzyme mimic derived from transition metal nanoparticles to enhance enzymic catalytic performances, may provide a versatile and facile technique for designing highly efficient and multi-functional bio-catalysts. After reading the article, we found that the author used ABTS Diammonium(cas: 30931-67-0Synthetic Route of C18H24N6O6S4)

ABTS Diammonium(cas: 30931-67-0) belongs to anime. The reaction of alkyl halides, R―X, where X is a halogen, or analogous reagents with ammonia (or amines) is useful with certain compounds. Not all alkyl halides are effective reagents; the reaction is sluggish with secondary alkyl groups and fails with tertiary ones. Its usefulness is largely confined to primary alkyl halides (those having two hydrogen atoms on the reacting site).Synthetic Route of C18H24N6O6S4

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Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Agarwal, Charu; Hofmann, Tamas; Pasztory, Zoltan published their research in Chemical Engineering and Processing on February 28 ,2021. The article was titled 《Low-frequency, green sonoextraction of antioxidants from tree barks of Hungarian woodlands for potential food applications》.Reference of ABTS Diammonium The article contains the following contents:

The present work evaluates and compares the antioxidant capacities of bioactive constituents in the barks of ten common wood species from Hungary (Quercus rubra, Prunus serotina, Quercus robur, Betula pendula, Fraxinus excelsior, Robinia pseudoacacia, Carpinus betulus, Picea abies, Alnus glutinosa, Pinus sylvestris). Low-frequency ultrasound was used for intensification of extraction from the bark to obtain extracts rich in polyphenolic antioxidants with potential applications in the food industry. The extractions were carried out in different aqueous organic solvents- ethanol 80% and acetone 80% at optimized conditions. The overall antioxidant capacity of the extracts was estimated by the combined evaluation of Folin-Ciocalteu total phenol content (TPC), 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and ferric reducing ability of plasma (FRAP) assays using a scoring system. Aqueous ethanol had better extraction efficiency than aqueous acetone as a solvent medium. Of all the investigated species, Quercus robur showed the maximum antioxidant capacity with TPC of 105.88 ± 17.75 mg GAE/g dw, DPPH (IC50) of 1.90 ± 0.10μg/mL, ABTS of 437.09 ± 36.22 mg TE/g dw and FRAP of 102.62 ± 8.69 mg AAE/g dw. The polyphenolic characterization of Quercus robur, Robinia pseudoacacia and Fraxinus excelsior was done by liquid chromatog./tandem mass spectrometry. In the part of experimental materials, we found many familiar compounds, such as ABTS Diammonium(cas: 30931-67-0Reference of ABTS Diammonium)

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Examples of direct uses of amines and their salts are as corrosion inhibitors in boilers and in lubricating oils (morpholine), as antioxidants for rubber and roofing asphalt (diarylamines), as stabilizers for cellulose nitrate explosives (diphenylamine), as protectants against damage from gamma radiation (diarylamines), as developers in photography (aromatic diamines), as flotation agents in mining, as anticling and waterproofing agents for textiles, as fabric softeners, in paper coating, and for solubilizing herbicides.Reference of ABTS Diammonium

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Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Recommanded Product: ABTS DiammoniumOn March 4, 2020, Gaikwad, Adwait; Hlushko, Hanna; Karimineghlani, Parvin; Selin, Victor; Sukhishvili, Svetlana A. published an article in ACS Applied Materials & Interfaces. The article was 《Hydrogen-Bonded, Mechanically Strong Nanofibers with Tunable Antioxidant Activity》. The article mentions the following:

We report on mech. strong, water-insoluble hydrogen-bonded nanofiber mats composed of a hydrophilic polymer and a natural polyphenol that exhibit prolonged antioxidant activity. The high performance of fibrous mats resulted from the formation of a network of hydrogen bonds between a low-mol.-weight polyphenol (tannic acid, TA) and a water-soluble polymer (polyvinylpyrrolidone, PVP) and could be precisely controlled by the TA-to-PVP ratio. Dramatic enhancement (5- to 10-fold) in tensile strength, toughness, and Young’s moduli of the PVP/TA fiber mats (as compared to those of pristine PVP fibers) was achieved at the maximum d. of hydrogen bonds, which occurred at ∼0.2-0.4 M fractions of TA. The formation of hydrogen bonds was confirmed by an increase in the glass-transition temperature of the polymer after binding with TA. When exposed to water, the fibers exhibited composition- and pH-dependent stabilities, with the TA-enriched fibers fully preserving their integrity in acidic and neutral media. Importantly, the fiber mats exhibited strong antioxidant activity with dual (burst and prolonged) activity profiles, which could be controlled via fiber composition, a feature useful for controlling radical-scavenging rates in environmental and biol. applications. In addition to this study using ABTS Diammonium, there are many other studies that have used ABTS Diammonium(cas: 30931-67-0Recommanded Product: ABTS Diammonium) was used in this study.

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Amines can be classified according to the nature and number of substituents on nitrogen. Aliphatic amines contain only H and alkyl substituents. Aromatic amines have the nitrogen atom connected to an aromatic ring.Important amines include amino acids, biogenic amines, trimethylamine, and aniline. Inorganic derivatives of ammonia are also called amines, such as monochloramine (NClH2).Recommanded Product: ABTS Diammonium

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

Formula: C18H24N6O6S4On June 8, 2022, Chalmpes, Nikolaos; Patila, Michaela; Kouloumpis, Antonios; Alatzoglou, Christina; Spyrou, Konstantinos; Subrati, Mohammed; Polydera, Angeliki C.; Bourlinos, Athanasios B.; Stamatis, Haralambos; Gournis, Dimitrios published an article in ACS Applied Materials & Interfaces. The article was 《Graphene oxide-cytochrome C multilayered structures for biocatalytic applications: Role of surfactant in Langmuir-Schaefer layer deposition》. The article mentions the following:

Graphene, a two-dimensional single-layer carbon allotrope, has attracted tremendous scientific interest due to its outstanding physicochem. properties. Its monat. thickness, high sp. surface area, and chem. stability render it an ideal building block for the development of well-ordered layered nanostructures with tailored properties. Herein, biohybrid graphene-based layer-by-layer structures are prepared by means of conventional and surfactant-assisted Langmuir-Schaefer layer deposition techniques, whereby cytochrome C mols. are accommodated within ordered layers of graphene oxide. The biocatalytic activity of the as-developed nanobio-architectures toward the enzymic oxidation of 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt and decolorization of pinacyanol chloride is tested. The results show that the multilayer structures exhibit high biocatalytic activity and stability in the absence of surfactant mols. during the deposition of the monolayers. In the experimental materials used by the author, we found ABTS Diammonium(cas: 30931-67-0Formula: C18H24N6O6S4)

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Halogenation, in which one or more hydrogen atoms of an amine is replaced by a halogen atom, occurs with chlorine, bromine, and iodine, as well as with some other reagents, notably hypochlorous acid (HClO). With primary amines the reaction proceeds in two stages, producing N-chloro- and N,N-dichloro-amines, RNHCl and RNCl2, respectively. With tertiary amines, an alkyl group may be displaced by a halogen.Formula: C18H24N6O6S4

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

The author of 《The reactivity of dopamine precursors and metabolites towards ABTS·-: an experimental and theoretical study》 were Dimic, Dusan; Milenkovic, Dejan; Markovic, Zoran; Markovic, Jasmina Dimitric. And the article was published in Journal of the Serbian Chemical Society in 2019. Reference of ABTS Diammonium The author mentioned the following in the article:

The antiradical activity of L-3,4-dihydroxyphenylalanine (L-DOPA), dihydroxyphenylacetic acid (DOPAC), homovanillic acid and tyrosine towards 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt radi- cal (ABTS·-) was investigated exptl. and theor. by UV-Vis spectroscopy and the DFT theory. The importance of the catechol moiety for this reaction was proven due to the formation of intramol. hydrogen bond in the formed anions and radicals. The results indicated L-DOPA and DOPAC were more potent radical scavengers than homovanillic acid and tyrosine just because of intramol. hydrogen bond formation. Based on exptl. spectra, it was proved that electron transfer led to the reduction of ABTS·. The values of thermodn. parameters were used to predict the preferred mech- anism. The reaction rates were calculated for the electron transfer processes and it was shown that these were both kinetically and thermodynamically driven processes. Based on the reaction rate values, thermodn. para- meters, and present species, as determined by electronic spectra, it was con- cluded that single proton loss electron transfer (SPLET) is the dominant react- ion mechanism in the investigated system. After reading the article, we found that the author used ABTS Diammonium(cas: 30931-67-0Reference of ABTS Diammonium)

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Reduction of nitro compounds, RNO2, by hydrogen or other reducing agents produces primary amines cleanly (i.e., without a mixture of products), but the method is mostly used for aromatic amines because of the limited availability of aliphatic nitro compounds. Reduction of nitriles and oximes (R2C=NOH) also yields primary amines.Reference of ABTS Diammonium

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica

《Phytochemical profile and comparative anti-radical scavenging activities of n-hexane extracts of indigenous Zingiber officinale and Curcuma longa》 was written by Nweze, Chibuzo Carole; Dingwoke, Emeka John; Adamude, Fatima Amin; Nwobodo, Nwobodo Ndubuisi. Synthetic Route of C18H24N6O6S4 And the article was included in Free Radicals and Antioxidants in 2019. The article conveys some information:

Objectives: Free radical scavenging activities of n-haxane extracts of indigenous Curcuma longa and Zingiber officinale was investigated and compared to CellGevity; a nutraceutical antioxidant supplement. Methods: We used 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical, 2,2′-Azino-bis3-ethylbenzothialine-6-sulfonic acid (ABTS) radical cations and hydrogen peroxide (H2O2) to determine free radical scavenging activities of the extracts The ability of the extracts to scavenge free radicals was determined following the discoloration of the solution mixtures, measured spectrophotometrically. The reducing power efficacy of the extracts was determined by their ability to reduce Fe3+ to Fe2+ ions. Results:Curcuma longa and Zingiber officinale have more free radical scavenging power compared to CellGevity. Curcuma longa has more scavenging power against DPPH and H2O2 system, while Zingiber officinale has more scavenging power against ABTS cations. CellGevity had the least scavenging activity against the free radicals, as observed in this study. The highest phenolic, flavonoid, Vitamin C, Vitamin B1 and Vitamin B2 quantified were found in Curcuma longa and Zingiber officinale compared to CellGevity. Conclusion: The indigenous Curcuma longa and Zingiber officinale are natural sources of effective antioxidants with more scavenging power compared to a standard CellGevity nutraceutical. In the part of experimental materials, we found many familiar compounds, such as ABTS Diammonium(cas: 30931-67-0Synthetic Route of C18H24N6O6S4)

ABTS Diammonium(cas: 30931-67-0) belongs to anime. Nitrous acid converts secondary amines (aliphatic or aromatic) to N-nitroso compounds (nitrosamines): R2NH + HNO2 → R2N―NO. Some nitrosamines are potent cancer-inducing substances, and their possible formation is a serious consideration when nitrites, which are salts of nitrous acid, are present in foods or pharmaceutical preparations. Tertiary amines give rise to nitrosamines more slowly; an alkyl group is eliminated as an aldehyde or ketone, along with nitrous oxide, N2O.Synthetic Route of C18H24N6O6S4

Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica