Tag: M.W:100-200

7709-58-2, Name is 4-(Chloromethyl)thiazole hydrochloride, molecular formula is C4H5Cl2NS, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 7709-58-2, COA of Formula: C4H5Cl2NS

Thiazoloquinoline and thiazolonaphthyridine compounds having an aryloxy or arylalkyleneoxy substituent at the 6-, 7-, 8-, or 9-position, pharmaceutical compositions containing the compounds, intermediates, and methods of making and methods of use of these compounds as immunomodulators, for modulating cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.COA of Formula: C4H5Cl2NS. In my other articles, you can also check out more blogs about 7709-58-2

Reference：
Thiazole | C3H4735NS – PubChem,
Thiazole | chemical compound | Britannica

2605-14-3, Name is 2-Chloro-6-methoxybenzo[d]thiazole, molecular formula is C8H6ClNOS, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 2605-14-3, Computed Properties of C8H6ClNOS

The preclinical characterization of novel octahydropyrrolo[3,4-c]pyrroles that are potent and selective orexin-2 antagonists is described. Optimization of physicochemical and DMPK properties led to the discovery of compounds with tissue distribution and duration of action suitable for evaluation in the treatment of primary insomnia. These selective orexin-2 antagonists are proven to promote sleep in rats, and this work ultimately led to the identification of a compound that progressed into human clinical trials for the treatment of primary insomnia. The synthesis, SAR, and optimization of the pharmacokinetic properties of this series of compounds as well as the identification of the clinical candidate, JNJ-42847922 (34), are described herein.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Computed Properties of C8H6ClNOS. In my other articles, you can also check out more blogs about 2605-14-3

Reference：
Thiazole | C3H3057NS – PubChem,
Thiazole | chemical compound | Britannica

Synthetic Route of 73931-63-2. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 73931-63-2, Name is Methyl benzo[d]thiazole-6-carboxylate

An unexpected ring-contraction from benzo[b]pyrazino[1,2-d][1,4]thiazine-1,4-diones (6) to benzo[4,5]thiazolo[3,2-a]pyrazine-1,4-diones (7) has been developed. The preliminary mechanistic studies showed the transformation contained two independent steps: the first step is the formation of a Michael adduct upon the addition of the protic solvent, in the presence of base, to the C-2-C-3 double bond of compound 6, and the second step is a ring-contraction induced by oxygen via the migration of sulfur atom from C-2 to C-3 position. And its scope is also studied.

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Reference：
Thiazole | C3H8520NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.1603-91-4, Name is 4-Methylthiazol-2-amine, molecular formula is C4H6N2S. In a Article，once mentioned of 1603-91-4, Quality Control of: 4-Methylthiazol-2-amine

Dihydropyridines with 1,4,4-trisubstitution were synthesized and tested for antihypertensive activity in a spontaneously hypertensive rat model. This substitution pattern on the dihydropyridine nucleus differs markedly from that found most active in the structure-activity relationship established for nifedipine-like compounds. However, some were found to significantly lower blood pressure at testing doses (30 mg/kg, ip and 100 mg/kg, po) for up to 24 h. Methyl 1,4-dihydro-4,4-dimethyl-1-pyridinepropanoate (2-1), for example, lowered blood pressure 71 mmHg at 30 mg/kg, ip and the effect endured for greater than 24 h. Unlike prototypical dihydropyridines such as nifedipine, these compounds did not seem to have any effect on calcium channels.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Quality Control of: 4-Methylthiazol-2-amine, you can also check out more blogs about1603-91-4

Reference：
Thiazole | C3H9813NS – PubChem,
Thiazole | chemical compound | Britannica

Application of 348-40-3. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 348-40-3, Name is 6-Fluorobenzo[d]thiazol-2-amine

Compounds of the Formula I: STR1 useful in the treatment of thrombin and trypsin related disorders.

If you are hungry for even more, make sure to check my other article about 348-40-3. Application of 348-40-3

Reference：
Thiazole | C3H10507NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.61291-21-2, Name is 5-Methylthiazole-2-carboxylic acid, molecular formula is C5H5NO2S. In a Patent，once mentioned of 61291-21-2, COA of Formula: C5H5NO2S

The present invention discloses novel isoquinoline carboxamide derivatives which are HIV protease inhibitors or prodrugs thereof, a process for their manufacture, pharmaceutical compositions and the use of such compounds in medicine. In particular, the compounds are hydroxyethylamine tripeptide mimetics which act as inhibitors of the HIV aspartyl protease, an essential enzyme in the replicative life cycle of HIV. Consequently, the compounds of this invention may be advantageously used in the treatment of HIV infection, either alone or in combination with other inhibitors of HIV viral replication or with pharmacoenhancers such as cytochrome P450 inhibitors.

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 61291-21-2 is helpful to your research., COA of Formula: C5H5NO2S

Reference：
Thiazole | C3H6512NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.121-66-4, Name is 5-Nitrothiazol-2-amine, molecular formula is C3H3N3O2S. In a Article，once mentioned of 121-66-4, Formula: C3H3N3O2S

The first examples of negative solvatochromism in neutral azo dyes containing both strongly electron-donating bis-(dialkylamino)thiazolyl and electron-withdrawing 4-(trifluoromethylsulfonyl)phenyl or 2-thiazolyl moieties are reported.

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 121-66-4 is helpful to your research., Formula: C3H3N3O2S

Reference：
Thiazole | C3H9430NS – PubChem,
Thiazole | chemical compound | Britannica

Related Products of 2602-85-9. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 2602-85-9, Name is Benzo[d]thiazole-2-carbonitrile

Arene and heteroarenediazonium o-benzenedisulfonimides can be used as efficient reagents in Sandmeyer cyanation. This work reports such reactions carried out by us under very mild conditions using tetrabutyl ammonium cyanide as a safe cyanide source and, interestingly, without the need for a Cu catalyst. The reactions have given rise to aryl nitriles in good yields (25 examples, average yield 75%). A good amount of o-benzenedisulfonimide was recovered from each reaction and then reused to prepare other salts. Mechanistic insights have allowed us to highlight the fundamental role of the o-benzenedisulfonimide anion as an electron transfer agent.

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Reference：
Thiazole | C3H7555NS – PubChem,
Thiazole | chemical compound | Britannica

Application of 105827-91-6. Let’s face it, organic chemistry can seem difficult to learn. Especially from a beginner’s point of view. Like 105827-91-6, Name is 2-Chloro-5-(chloromethyl)thiazole. In a document type is Patent, introducing its new discovery.

A compound of Formula (2) is disclosed: wherein R1, MA and MB are as defined in the disclosure. Also disclosed is a method for preparing a compound of Formula (1): wherein R1 and X are as defined in the disclosure comprising contacting a compound of Formula (2) with a halogenating agent. Also disclosed is a method for preparing a compound of Formula (4): wherein R1, R3 and R4 are as defined in the disclosure, comprising reacting a compound of Formula (5): wherein R3 and R4 are as defined in the disclosure with a compound of Formula (1), with a compound of Formula (1), the process of preparing the compound of Formula (4) includes the step of preparing the compound of Formula (1) from the compound of Formula (2) by the method disclosed above. Also disclosed is compound that is methyl 3,5-dichlorobenzeneethanimidate methyl 3,5 dichlorobenzeneethanimidate or ethyl 3,5 dichlorobenzeneethanimidate or salts thereof.

If you are interested in 105827-91-6, you can contact me at any time and look forward to more communication.Application of 105827-91-6

Reference：
Thiazole | C3H2997NS – PubChem,
Thiazole | chemical compound | Britannica

Synthetic Route of 278183-10-1, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 278183-10-1, C5H6N2O2S. A document type is Article, introducing its new discovery.

6-(Variously substituted)-3-methoxy(unsubstituted, dimethylaminomethyl, acetamidomethyl and benzamidomethyl)-2-benzyl(phenethyl, biphenyl-4′-yl, 6′-methylnaphthalen-2′-yl, t-butyl and cyclohexyl)imidazo<1,2-b>pyridazines have been prepared and examined for activity in the central nervous system.Of these, 2-benzyl-3-methoxy-6-(3′-methoxybenzylamino)imidazo<1,2-b>pyridazine (IC50 88 nM) bound most strongly to rat brain membrane.In general, the order of activity for groups at the 2-position was Ph>PhCH2>PhCH2CH2>C6H4Ph-p, 6′-methylnaphthalen-2′-yl, c-C6H11 or But.

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Reference：
Thiazole | C3H8472NS – PubChem,
Thiazole | chemical compound | Britannica