Tag: M.W:100-200

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 63754-97-2, Name is 4-Fluorobenzo[d]thiazol-2(3H)-one, Product Details of 63754-97-2.

A process for producing N-alkylbenzothiazolone derivatives of the formula (I), STR1 wherein R1 is a hydrogen, chlorine, bromine, fluorine atom or a methyl group, and R2 is an alkyl group having 1 to 5 carbon atoms, from 2-halogenobenzothiazole derivatives of the formula (II), STR2 wherein R1 is as defined above and X is a chlorine, bromine or fluorine atom, which is a starting material, through the intermediate of 2-alkoxybenzothiazole derivatives of the formula (III), STR3 wherein R1 and R2 are as defined above, or benzothiazolone derivatives of the formula (IV), STR4 wherein R1 is as defined above.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Product Details of 63754-97-2. In my other articles, you can also check out more blogs about 63754-97-2

Reference：
Thiazole | C3H5284NS – PubChem,
Thiazole | chemical compound | Britannica

Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 479028-70-1, C8H4FNO2S. A document type is Patent, introducing its new discovery., name: 4-Fluorobenzo[d]thiazole-2-carboxylic acid

PROBLEM TO BE SOLVED: To provide a compound that has excellent glucokinase (GK) activating action and is useful as a pharmaceutical. SOLUTION: The present invention provides a 2-pyridone compound represented by formula [1], and a tautomer or stereoisomer of the compound, or their pharmacologically acceptable salts, or their solvates (where R1 is RA-ZA-; RA is any of a carboxy group, a sulfo group or formula [5]). COPYRIGHT: (C)2016,JPO&INPIT

Interested yet? Keep reading other articles of 479028-70-1!, name: 4-Fluorobenzo[d]thiazole-2-carboxylic acid

Reference：
Thiazole | C3H5285NS – PubChem,
Thiazole | chemical compound | Britannica

Synthetic Route of 101258-16-6. Let’s face it, organic chemistry can seem difficult to learn. Especially from a beginner’s point of view. Like 101258-16-6, Name is 1-(2-Aminothiazol-4-yl)ethanone. In a document type is Patent, introducing its new discovery.

The present invention relates to hydroximoyl – tetrazole derivatives of formula (I), their process of preparation, preparation intermediate compounds, their use as fungicide active agents, particularly in the form of fungicide compositions and methods for the control of phytopathogenic fungi, notably of plants, using these compounds or compositions.

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Reference：
Thiazole | C3H217NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 877385-86-9, Name is 2-Cyclopropylthiazole-5-carbaldehyde, molecular formula is C7H7NOS. In a Patent，once mentioned of 877385-86-9, Formula: C7H7NOS

The present invention relates to novel Heterocycle-Substituted Tetracyclic Compounds of Formula (I): (I) and pharmaceutically acceptable salts thereof, wherein A, A’, R 2 R 3, R 4 and R are as defined herein. The present invention also relates to compositions comprising at least one Heterocycle-Substituted Tetracyclic Compound, and methods of using the Heterocycle-Substituted Tetracyclic Compounds for treating or preventing HCV infection in a patient.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Formula: C7H7NOS. In my other articles, you can also check out more blogs about 877385-86-9

Reference：
Thiazole | C3H3192NS – PubChem,
Thiazole | chemical compound | Britannica

Related Products of 106092-11-9, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 106092-11-9, Name is (R)-4,5,6,7-Tetrahydro-benzothiazole-2,6-diamine, molecular formula is C7H11N3S. In a Article，once mentioned of 106092-11-9

Bacterial DNA gyrase and topoisomerase IV are essential enzymes that control the topological state of DNA during replication and validated antibacterial drug targets. Starting from a library of marine alkaloid oroidin analogues, we identified low micromolar inhibitors of Escherichia coli DNA gyrase based on the 5,6,7,8-tetrahydroquinazoline and 4,5,6,7-tetrahydrobenzo[1,2-d]thiazole scaffolds. Structure-based optimization of the initial hits resulted in low nanomolar E. coli DNA gyrase inhibitors, some of which exhibited micromolar inhibition of E. coli topoisomerase IV and of Staphylococcus aureus homologues. Some of the compounds possessed modest antibacterial activity against Gram positive bacterial strains, while their evaluation against wild-type, impA and DeltatolC E. coli strains suggests that they are efflux pump substrates and/or do not possess the physicochemical properties necessary for cell wall penetration. Our study provides a rationale for optimization of this class of compounds toward balanced dual DNA gyrase and topoisomerase IV inhibitors with antibacterial activity.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 106092-11-9 is helpful to your research., Related Products of 106092-11-9

Reference：
Thiazole | C3H33NS – PubChem,
Thiazole | chemical compound | Britannica

In an article, published in an article, once mentioned the application of 80416-76-8, Name is 7-Chlorobenzo[d]thiazol-2(3H)-one,molecular formula is C7H4ClNOS, is a conventional compound. this article was the specific content is as follows.HPLC of Formula: C7H4ClNOS

Analgesic and antipyretic pharmaceutical dosage unit compositions containing as an active ingredient a compound of the formula STR1 wherein R5 is methyl or methoxy, and R4, R6 and R7 are hydrogen; or R6 is fluorine or chlorine, and R4, R5 and R7 are hydrogen; or R7 is chlorine, and R4, R5 and R6 are hydrogen; or R5 and R6 are methoxy, and R4 and R7 are hydrogen; or R4 is methyl or chlorine, and R5, R6 and R7 are hydrogen; and methods of using said compounds as analgesics and antipyretics.

Do you like my blog? If you like, you can also browse other articles about this kind. HPLC of Formula: C7H4ClNOS. Thanks for taking the time to read the blog about 80416-76-8

Reference：
Thiazole | C3H7429NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.133047-46-8, Name is 2-Isopropylthiazole-4-carbaldehyde, molecular formula is C7H9NOS. In a Patent，once mentioned of 133047-46-8, COA of Formula: C7H9NOS

This invention is directed to benzenesulfonamide compounds, as stereoisomers, enantiomers, tautomers thereof or mixtures thereof; or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment of diseases or conditions associated with voltage-gated sodium channels, such as epilepsy.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.COA of Formula: C7H9NOS, you can also check out more blogs about133047-46-8

Reference：
Thiazole | C3H3534NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 62266-81-3, Name is 6-Chlorobenzo[d]thiazol-2(3H)-one, molecular formula is C7H4ClNOS. In a Patent，once mentioned of 62266-81-3, Product Details of 62266-81-3

The invention discloses a carbonyl sulfur and disulfide as a starting material to synthesize benzothiazole – 2 – ketone derivatives. The method includes the disulfide, inorganic sulfide is mixed with organic solvent, access sufficient COS reaction, the reaction liquid concentration purification to obtain the surfactant-benzothiazole – 2 – ketone derivatives. The invention relates to the activation of the catalyst is an inorganic sulfide, is cheap and easily available; catalytic system is relatively simple, in addition to the reactant and inorganic sulfide outer does not add any other cocatalyst; direct dehydration in the reaction process, does not need to add other dehydrating agent, improves the atom economy; catalytic system wide adaptability, is suitable for the synthesis of fine chemicals with high added value, and for each of the high value-added fine chemicals has very strong substrate applicability; reaction is the normal, atmospheric or low pressure, the risk of; short reaction time, improving the efficiency. (by machine translation)

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.Product Details of 62266-81-3, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 62266-81-3, in my other articles.

Reference：
Thiazole | C3H6978NS – PubChem,
Thiazole | chemical compound | Britannica

169260-97-3, Name is 5-(Trifluoromethyl)thiazol-2-amine, molecular formula is C4H3F3N2S, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 169260-97-3, Recommanded Product: 5-(Trifluoromethyl)thiazol-2-amine

The present invention relates to compounds of the formula I as described below or a tautomer or a pharmaceutically acceptable salt thereof; to a pharmaceutical composition containing such compounds; and to said compounds of the formula I or a tautomer or a pharmaceutically acceptable salt thereof for use as a medicament, especially for use in the treatment or prevention of a disease or disorder selected from the group consisting of an inflammatory disease, a hyperproliferative disease or disorder, a hypoxia-related pathology and a disease characterized by excessive vascularization, wherein X1 is CR1 or N; X2 is CR2 or N; X3 is CR3 or N; X4 is CR4 or N; Y1 is N, NR5a, S, O or CR5b; Y2 is N, NR5c, S, O or CR5d; Z is N or C; with the proviso that at most two of X1, X2, X3 and X4 are N; with the proviso that Y1 is not O if Y2 is CR5d and simultaneously Z is C; with the proviso that Y1 and Y2 are not both simultaneously O or S; with the proviso that at least one of Y1, Y2 and Z is a heteroatom or heteroatom-containing group; L1 is a bond, optionally substituted C1-C6-alkylene or C3-C8-cycloalkylene; L2 is a bond, optionally substituted C1-C6-alkylene, C3-C8-cycloalkylene etc.; A is 3-, 4-, 5-, 6-, 7- or 8-membered optionally substituted, saturated, partially unsaturated or maximally unsaturated carbocyclic or heterocyclic ring; or L2-A forms a group C1-C6-alkylene-OR13, C1-C6-alkylene-SR14 or C1-C6-alkylene-NR15R16; and R1, R2, R3, R4, R5a, R5b, R5c, R5d, R6, R13, R14, R15 and R16 are as defined in the claims and the description.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Recommanded Product: 5-(Trifluoromethyl)thiazol-2-amine. In my other articles, you can also check out more blogs about 169260-97-3

Reference：
Thiazole | C3H6031NS – PubChem,
Thiazole | chemical compound | Britannica

Reference of 19847-11-1, Chemistry can be defined as the study of matter and the changes it undergoes. You’ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology.19847-11-1, Name is 4-(Pyrazin-2-yl)thiazol-2-amine, molecular formula is C7H6N4S. In a patent, introducing its new discovery.

A series of 2-aminothiazoles was synthesized based on a HTS scaffold from a whole-cell screen against Mycobacterium tuberculosis (Mtb). The SAR shows the central thiazole moiety and the 2-pyridyl moiety at C-4 of the thiazole are intolerant to modification. However, the N-2 position of the aminothiazole exhibits high flexibility and we successfully improved the antitubercular activity of the initial hit by more than 128-fold through introduction of substituted benzoyl groups at this position. N-(3-Chlorobenzoyl)-4-(2-pyridinyl) -1,3-thiazol-2-amine (55) emerged as one of the most promising analogues with a MIC of 0.024 muM or 0.008 mug/mL in 7H9 media and therapeutic index of nearly ?300. However, 55 is rapidly metabolized by human liver microsomes (t1/2 = 28 min) with metabolism occurring at the invariant aminothiazole moiety and Mtb develops spontaneous low-level resistance with a frequency of ?10-5.

If you are interested in 19847-11-1, you can contact me at any time and look forward to more communication.Reference of 19847-11-1

Reference：
Thiazole | C3H4823NS – PubChem,
Thiazole | chemical compound | Britannica