Tag: M.W:100-200

In an article, published in an article, once mentioned the application of 40283-46-3, Name is 2-Aminothiazole-5-carboxylic acid,molecular formula is C4H4N2O2S, is a conventional compound. this article was the specific content is as follows.Application In Synthesis of 2-Aminothiazole-5-carboxylic acid

One kind has azo thiazole structure suitable for supercritical carbon dioxide water-free wool dyeing of the disperse dye and its preparation method (by machine translation)

The invention provides a with azo thiazole structure suitable for supercritical carbon dioxide water-free wool dyeing of the disperse dye, preparation method thereof and dyeing method, the dye, having the general formula I of the structure. The dye can be used in the supercritical carbon dioxide water-free wool dyeing, such compound in the supercritical carbon dioxide has a certain level of solubility, while at the same time utilize active group and wool in the amino or hydroxy group of the chemical reaction, the reaction product to the supercritical carbon dioxide dyeing device non-corrosiveness. In the general formula I: m, n each is an integer; X, Y are independently selected from one of – H, – CN, – CH3 O, – COOCH3 or R0 R is selected from1 , R2 Or R3 ; Ar Ar selected from1 ; (by machine translation)

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Reference：
Thiazole | C3H2324NS – PubChem,
Thiazole | chemical compound | Britannica

In an article, published in an article, once mentioned the application of 120237-76-5, Name is 5-Methylthiazole-4-carboxylic acid,molecular formula is C5H5NO2S, is a conventional compound. this article was the specific content is as follows.Application In Synthesis of 5-Methylthiazole-4-carboxylic acid

5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-a]PYRAZ1NE DERIVATIVES AS P2X7 MODULATORS

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein A is hydrogen, C1-4 alkyl, C3-6 cycloalkyl, C1-3 alkoxy, C1-3 alkoxy C1-4 alkyl, C1-2 fluoroalkyl, halogen, NR6 R7, optionally substituted heteroaryl (Het), or optionally substituted phenyl, and R1, R2, R3, R4, R5, R6 and R7 are as defined in the description. The compounds or salts are thought to modulate P2X7 receptor function and to be capable of antagonizing the effects of ATP at the P2X7 receptor. The invention also provides the use of the compound or salt in the treatment or prophylaxis of, for example, inflammatory pain, neuropathic pain, visceral pain, rheumatoid arthritis, osteoarthritis or neurodegenerative disorders.

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Reference：
Thiazole | C3H6529NS – PubChem,
Thiazole | chemical compound | Britannica

In an article, published in an article, once mentioned the application of 850429-61-7, Name is Methyl2-chloro-4-thiazolecarboxylate,molecular formula is C5H4ClNO2S, is a conventional compound. this article was the specific content is as follows.Safety of Methyl2-chloro-4-thiazolecarboxylate

Liquid-phase oxidation of 1-isopropyl- and 1-ethyl-4-methoxybenzenes with oxygen to hydroperoxides

A study was carried out on the kinetics of free-radical chain oxidation of 1-isopropyl-4-methoxybenzene (1a) and 1-ethyl-4-methoxybenzene (1b) with oxygen in the liquid phase to yield 1-methyl-1-(4-methoxyphenyl)ethyl hydroperoxide (2a) and 1-(4-methoxyphenyl)ethyl hydroperoxide (2b). The oxidizability of 1a and 1b was studied over the temperature range 50-100C. Long-term oxidations of 1a and 1b to the corresponding hydroperoxides were carried out and the properties and thermal stability of 2a were established.

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Reference：
Thiazole | C3H8632NS – PubChem,
Thiazole | chemical compound | Britannica

10200-59-6, Name is 2-Thiazolecarboxaldehyde, molecular formula is C4H3NOS, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 10200-59-6, category: thiazole

Comparison of inhibitory activity of isomeric triazolopyridine derivatives towards adenosine receptor subtypes or do similar structures reveal similar bioactivities?

The synthesis of an array of 8-amino-2-aryl-[1,2,4]triazolo[1,5-a]pyridine- 6-carboxyl amide derivatives is described for the first time. A subset of 20 derivatives were compared to their isomeric 5-amino-2-aryl-[1,2,4]triazolo[1,5- a]pyridine-7-carboxyl amide counterparts with regard to their potential to inhibit the human adenosine 2a (hA2a) receptor and their selectivity against the human adenosine 1 (hA1) receptor. Based on the analysis of H-bond donor/acceptor capabilities of the isomeric triazolopyridine pairs it can be concluded that the H-bond donor strength of the free amino functionality is the main determinant for hA2a inhibitory activity and hA1 selectivity.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.category: thiazole. In my other articles, you can also check out more blogs about 10200-59-6

Reference：
Thiazole | C3H4122NS – PubChem,
Thiazole | chemical compound | Britannica

Electric Literature of 76874-79-8, Chemistry can be defined as the study of matter and the changes it undergoes. You’ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology.76874-79-8, Name is 2-Amino-4-chlorothiazole-5-carbaldehyde, molecular formula is C4H3ClN2OS. In a patent, introducing its new discovery.

Compounds and methods for kinase modulation, and indications therefor

Compounds and salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof and uses thereof are described. In certain aspects and embodiments, the described compounds or salts thereof, formulations thereof, conjugates thereof, derivatives thereof, or forms thereof are active on Fms protein kinase, or on Fms and Kit protein kinase, or on Fms and Flt-3 protein kinase. Also described are methods of use thereof to treat diseases and conditions, including diseases and conditions associated with activity of Fms protein kinase, Kit protein kinase, or Flt-3 protein kinase including rheumatoid arthritis, osteoarthritis, multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, glomerulonephritis, interstitial nephritis, Lupus nephritis, tubular necrosis, diabetic nephropathy, renal hypertrophy, acute myeloid leukemia, melanoma, multiple myeloma, metastatic breast cancer, prostate cancer, pancreatic cancer, neurofibromatosis, brain metastases, and gastrointestinal stromal tumors.

If you are interested in 76874-79-8, you can contact me at any time and look forward to more communication.Electric Literature of 76874-79-8

Reference：
Thiazole | C3H1928NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 193017-26-4, Name is 4-(Thiazol-2-yl)aniline, molecular formula is C9H8N2S. In a Patent，once mentioned of 193017-26-4, Computed Properties of C9H8N2S

COMPOUNDS USEFUL AS KINASE INHIBITORS

This invention relates to novel compounds. The compounds of the invention are tyrosine kinase inhibitors. Specifically, the compounds of the invention are useful as inhibitors of Bruton’s tyrosine kinase (BTK).The invention also contemplates the use of the compounds for treating conditions treatable by the inhibition of Bruton’s tyrosine kinase, for example cancer, lymphoma, leukemia and immunological diseases.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.Computed Properties of C9H8N2S, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 193017-26-4, in my other articles.

Reference：
Thiazole | C3H4829NS – PubChem,
Thiazole | chemical compound | Britannica

Electric Literature of 41731-23-1. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 41731-23-1, Name is 2-Bromo-5-methylthiazole

A one-pot universal approach for transforming arylamines to aryl halides via reaction with sodium nitrite (NaNO2) and N-halosuccinimide (NXS) in DMF at room temperature under metal- and acid-free condition is described. This new protocol that is complementary to the Sandmeyer reaction, is suggested to involve the in situ generation of nitryl halide induce nitrosylation of aryl amine to form the diazo intermediate which is halogenated to furnish the aryl halide.

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Reference：
Thiazole | C3H2615NS – PubChem,
Thiazole | chemical compound | Britannica

In an article, published in an article, once mentioned the application of 3364-80-5, Name is Thiazole-4-carboxaldehyde,molecular formula is C4H3NOS, is a conventional compound. this article was the specific content is as follows.Quality Control of: Thiazole-4-carboxaldehyde

The compounds are 2-alkoxy(and 2-amino)-3-amino-2-heterocyclic-thiopropanamides, for example 2-methoxy-N-methyl-3-morpholino-2-(2-pyridyl)thiopropanamide, which are inhibitors of gastric acid secretion.

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Reference：
Thiazole | C3H9290NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.1603-91-4, Name is 4-Methylthiazol-2-amine, molecular formula is C4H6N2S. In a Patent，once mentioned of 1603-91-4, SDS of cas: 1603-91-4

A cyclopropane derivative represented by the following formula (I) or a pharmaceutically acceptable salt thereof has orexin receptor inhibitory action, and thus, is extremely useful as an agent for preventing or treating sleep disorder or dyssomnia caused by orexin, including insomnia as a typical example. wherein A1, A2 and A3 each independently represent an aryl group, a heterocyclyl group or the like, R> R2 and R3 each independently represent a hydrogen atom, a C1-6 alkyl group or the like, X represents an oxygen atom or the like, and L represents a bond or the like

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.SDS of cas: 1603-91-4, you can also check out more blogs about1603-91-4

Reference：
Thiazole | C3H9930NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.137-00-8, Name is 4-Methyl-5-thiazoleethanol, molecular formula is C6H9NOS. In a Patent，once mentioned of 137-00-8, SDS of cas: 137-00-8

Use of a novel class of NO-donating compounds, designed such that when NO is released from the compound a residue which is a naturally occurring metabolite is formed, in the treatment of inflammatory bowel diseases is disclosed.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.SDS of cas: 137-00-8, you can also check out more blogs about137-00-8

Reference：
Thiazole | C3H5326NS – PubChem,
Thiazole | chemical compound | Britannica