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Described herein are hepatitis B capsid assembly modulators and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of hepatitis B.

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Reference£º
Thiazole | C3H79NS – PubChem,
Thiazole | chemical compound | Britannica

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Related Products of 5198-86-7, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 5198-86-7, Name is (2-Bromothiazol-4-yl)methanol, molecular formula is C4H4BrNOS. In a Patent£¬once mentioned of 5198-86-7

The invention relates to a benzoxazole compound alkane ketones, and its in the preparation of the prevention and treatment of thromboembolic disease in the application. In particular, the invention relates to the general formula (I)) the compound, among them or their stereoisomers, geometric isomers, tautomers, nitrogen oxide, hydrate, solvate, metabolite, pharmaceutically acceptable salt or prodrug, the variables are defined in the specification. The invention also relates to the general formula (I) compound of formula its stereoisomers, geometric isomers, tautomers, nitrogen oxide, hydrate, solvate, metabolite, pharmaceutically acceptable salt or salt of a prodrug use as pharmaceuticals, in particular as used for the prevention and treatment of thromboembolic disease of use. (by machine translation)

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Reference£º
Thiazole | C3H43NS – PubChem,
Thiazole | chemical compound | Britannica

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Reference of 51640-52-9. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 51640-52-9, Name is 2-Aminothiazole-5-carbonitrile

The present invention relates to active polymorphs of 4-[2-(5-cyano-thiazol-2-ylamino)-pyridin-4-ylmethyl]-piperazine-1-carboxylic acid methylamide which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angio-genesis, cancer, tumor growth, atherosclerosis, age related macular degeneration, diabetic retinopathy, retinal ischemia, macular edema, inflammatory diseases, and the like in mammals.

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Reference£º
Thiazole | C3H2287NS – PubChem,
Thiazole | chemical compound | Britannica

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Reference of 10200-59-6. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 10200-59-6, Name is 2-Thiazolecarboxaldehyde

The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts or solvates thereof, wherein all the variables are as defined herein. These compounds are antagonists to alphanu- containing integrins. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating a disease, disorder, or condition associated with dysregulation of ay- containing integrins, such as pathological fibrosis, transplant rejection, cancer, osteoporosis, and inflammatory disorders, by using the compounds and pharmaceutical compositions.

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Reference£º
Thiazole | C3H4170NS – PubChem,
Thiazole | chemical compound | Britannica

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In an article, published in an article, once mentioned the application of 1123-93-9, Name is 1,3-Benzothiazol-5-amine,molecular formula is C7H6N2S, is a conventional compound. this article was the specific content is as follows.name: 1,3-Benzothiazol-5-amine

Compounds of Formula I with activity against HIV, including pharmaceutical compositions and methods for using these compounds in treating human immunodeficiency virus (HIV) infection, are set forth: Formula :(I)

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Reference£º
Thiazole | C3H316NS – PubChem,
Thiazole | chemical compound | Britannica

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The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.53266-94-7, Name is Ethyl 2-(2-aminothiazol-4-yl)acetate, molecular formula is C7H10N2O2S. In a Article£¬once mentioned of 53266-94-7, name: Ethyl 2-(2-aminothiazol-4-yl)acetate

The introduction of functional groups at the 4-position of beta-sultam ring was realized by the synthesis of mono- and disubstituted derivatives by reactions of N-silylated beta-sultams with electrophiles in the presence of BuLi or LDA. As electrophiles, ketones, chlorosilanes, a beta-sultam, CO 2, chloroformiate, halogen, azodicarboxylate, phenyltriazoledione, tosyl azide, 1,3,5-triazine, propyl nitrate, and phenyl isocyanate were used. Furthermore, a number of derivatives of these substitution products were synthesized. All products were characterized by standard spectroscopic methods, and conformations were studied, supported by calculation.

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Reference£º
Thiazole | C3H10734NS – PubChem,
Thiazole | chemical compound | Britannica

Discovery of 6973-51-9

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Application of 6973-51-9, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 6973-51-9, Name is 4-Nitrobenzo[d]thiazol-2-amine, molecular formula is C7H5N3O2S. In a Article£¬once mentioned of 6973-51-9

A series of compounds namely, 3-chloro-4-(2?,4?-dichlorophenyl) -4-methyl-1-(substituted-1?,3?-benzothiazol-2?-yl) -azetidin-2-ones 4a-j and 2-(2?,4?-dichlorophenyl)-2,5-dimethyl-3- (substituted-1?,3?-benzothiazol-2?-yl)-1,3-thiazolidin-4-ones 5a-j have been prepared by the reaction of schiff base derivatives 3 with chloroacetyl chloride in the presence of triethylamine and thiolactic acid, respectively. The schiff base derivatives 3 have been prepared by the condensation of substituted-2-aminobenzothiazole 1 with 2,4-dichloroacetophenone 2. The reactions have been carried out by microwave and conventional methods. The microwave assisted reactions are carried out in a “QPro-M modified microwave oven” made in Canada. Both the azetidinones and thiazolidinones are pharmacologically active and screened for their antibacterial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Salmonella typhi and antifungal activity against Candida albicans.

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Reference£º
Thiazole | C3H5882NS – PubChem,
Thiazole | chemical compound | Britannica

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Reference of 915030-08-9, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 915030-08-9, Name is 2-(Trifluoromethyl)thiazole-4-carboxylic acid, molecular formula is C5H2F3NO2S. In a Patent£¬once mentioned of 915030-08-9

The invention provides a compound of formula (I) or a salt thereof: wherein R2 is H, C1-3alkyl, n-butyl, C1-2fluoroalkyl, cyclopropyl, cyclobutyl, (cyclopropyl)methyl-, ?CN, or ?CH2OH; R3 is inter alia optionally substituted C4-7cycloalkyl or an optionally substituted heterocyclic group (aa), (bb) or (cc); Ra is H, methyl or ethyl; Rb is H or methyl; R4 is H, methyl, ethyl, n-propyl, ?C(O)-Me, or ?C(O)?C1fluoroalkyl; and R5 is: ?C(O)?(CH2)n?Ar, ?C(O)-Het, ?C(O)?C1-6alkyl, ?C(O)?C1 fluoroalkyl, ?C(O)?(CH2)2?C(O)?NR15bNR15b, ?C(O)?CH2?C(O)?NR15bNR15b, ?C(O)?NR15b?(CH2)m1?Ar, ?C(O)?NR15b?Het, ?C(O)?NR15b?C1-6alkyl, ?C(O)?NR5aR5b, ?S(O)2?(CH2)m2?Ar, ?S(O)2-Het, ?S(O)2?C1-6alkyl, or ?CH2?Ar; or R4 and R5 taken together are ?(CH2)p1?, ?(CH2)2?X5?(CH2)2?, ?C(O)?(CH2)p2?, ?C(O)?N(R15)?(CH2)p3?; or NR4R5 is of sub-formula (y), (y1), (y2) or (y3). The invention provides the use of the compounds as inhibitors of phosphodiesterase type IV (PDE4) and/or for the treatment and/or prophylaxis of inflammatory and/or allergic diseases such as COPD and the like.

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Reference£º
Thiazole | C3H1016NS – PubChem,
Thiazole | chemical compound | Britannica

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Reference of 1826-11-5, Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology.1826-11-5, Name is 2-Phenylthiazole, molecular formula is C9H7NS. In a patent, introducing its new discovery.

A self-contained photoacid generator for super acid along with the photoinduced 6pi-electrocyclization reaction of the terarylene backbone is demonstrated. The photoinitiated cationic polymerization of epoxy-monomers is achieved with an efficient photochemical quantum yield, Phiacid = 0.47.

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Reference£º
Thiazole | C3H3990NS – PubChem,
Thiazole | chemical compound | Britannica

Discovery of 2942-13-4

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Reference of 2942-13-4. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 2942-13-4, Name is 6-Methoxybenzo[d]thiazole

A Pd-catalyzed direct cross-coupling of 3-bromocoumarins with heteroarenes provided an efficient route to synthesizing 3-heteroarylcoumarins. The reaction scope for the transformation was fairly broad, affording modest to good yields of various 3-heteroarylcoumarin scaffolds, which are privileged structures and prevalent motifs in many biologically active compounds and fluorophores. The Royal Society of Chemistry 2012.

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Reference£º
Thiazole | C3H7217NS – PubChem,
Thiazole | chemical compound | Britannica