Tag: M.W:200-300

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 302964-02-9, Name is 2-Boc-Aminothiazole-5-carboxylic acid, molecular formula is C9H12N2O4S. In a Patent，once mentioned of 302964-02-9, Quality Control of: 2-Boc-Aminothiazole-5-carboxylic acid

This invention relates to novel 2-{6-[4-(2-hydroxy-ethyl)-piperazin-1-yl]-2-methyl-pyrimidin-4-ylamino}-thiazole-5-carboxylic acid (2-chloro-6-methyl-phenyl)-amide derivatives, and pharmaceutically acceptable acid addition salts thereof. The invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions beneficially treated by the inhibition of kinases including Src-kinase and Bcr-Abl kinase

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.Quality Control of: 2-Boc-Aminothiazole-5-carboxylic acid, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 302964-02-9, in my other articles.

Reference：
Thiazole | C3H2379NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 53218-26-1, Name is 6-Bromobenzo[d]thiazole, molecular formula is C7H4BrNS. In a Patent，once mentioned of 53218-26-1, Safety of 6-Bromobenzo[d]thiazole

[Object] To provide a compound having prostaglandin production-suppressing action and leukotriene production-suppressing action.[Means for solution] A compound represented by the formula (I): [In the formula, —- represents a single bond, or a double bond, Link represents a single bond, or a saturated or unsaturated straight hydrocarbon having 1 or 2 carbon atoms, W represents a single bond, oxygen atom, sulfur atom, N(Rw) etc., Rw represents hydrogen atom, an alkyl group having 1 to 8 carbon atoms etc, Rs represents -D-Rx etc., D represents a single bond, oxygen atom, sulfur atom etc., Rx represents a linear or branched saturated alkyl group having 3 to 8 carbon atoms etc., one of V1 and V2 represents Zx, and the other represents AR, Zx represents hydrogen atom, a linear or branched saturated alkyl group having 1 to 4 carbon atoms etc., AR represents a partially unsaturated or completely unsaturated condensed bicyclic carbon ring or heterocyclic ring, and Y represents hydrogen atom, a lower alkyl group having 1 to 4 carbon atoms etc.], or a salt thereof.[Object] To provide a compound having prostaglandin production-suppressing action and leukotriene production-suppressing action. [Means for solution] A compound represented by the formula (I): [In the formula, —- represents a single bond, or a double bond, Link represents a single bond, or a saturated or unsaturated straight hydrocarbon having 1 or 2 carbon atoms, W represents a single bond, oxygen atom, sulfur atom, N(Rw) etc., Rw represents hydrogen atom, an alkyl group having 1 to 8 carbon atoms etc, Rs represents -D-Rx etc., D represents a single bond, oxygen atom, sulfur atom etc., Rx represents a linear or branched saturated alkyl group having 3 to 8 carbon atoms etc., one of V 1 and V 2 represents Zx, and the other represents AR, Zx represents hydrogen atom, a linear or branched saturated alkyl group having 1 to 4 carbon atoms etc., AR represents a partially unsaturated or completely unsaturated condensed bicyclic carbon ring or heterocyclic ring, and Y represents hydrogen atom, a lower alkyl group having 1 to 4 carbon atoms etc.], or a salt thereof.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.Safety of 6-Bromobenzo[d]thiazole, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 53218-26-1, in my other articles.

Reference：
Thiazole | C3H6957NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 53218-26-1, Name is 6-Bromobenzo[d]thiazole, molecular formula is C7H4BrNS. In a Patent，once mentioned of 53218-26-1, name: 6-Bromobenzo[d]thiazole

The application relates to compounds of Formula (I’): which modulate the activity of a kinase (e.g., STK4), a pharmaceutical composition comprising the compound, and a method of treating or preventing a disease or disorder associated with the modulation of a kinase, such as STK4.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.name: 6-Bromobenzo[d]thiazole, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 53218-26-1, in my other articles.

Reference：
Thiazole | C3H6898NS – PubChem,
Thiazole | chemical compound | Britannica

Synthetic Route of 51618-30-5. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 51618-30-5, Name is 6-Bromobenzo[d]thiazole-2(3H)-thione

A copper-catalyzed iminyl radical-mediated C-C bond cleavage/cross-coupling tandem reaction of cyclobutanone oxime esters with aryl thiols in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) at room temperature was developed, and aryl cyanopropyl sulfides were smoothly synthesized in 20-88% yields. By altering the copper reagent and the molar ratio of cyclobutanone oxime ester/aryl thiol/DBU, substitutional product N-arylthio cyclobutanone imines were selectively generated in 50-91% yields. Using this protocol, C-S bond and N-S bond formations using aryl thiols as sulfur sources were realized under very mild conditions without the use of photocatalysis and electrocatalysis techniques.

If you are hungry for even more, make sure to check my other article about 51618-30-5. Synthetic Route of 51618-30-5

Reference：
Thiazole | C3H6972NS – PubChem,
Thiazole | chemical compound | Britannica

4175-77-3, Name is 2,4-Dibromothiazole, molecular formula is C3HBr2NS, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 4175-77-3, HPLC of Formula: C3HBr2NS

The present invention relates to novel compounds that can be employed in the diagnosis, treatment, alleviation or prevention of a group of disorders and abnormalities associated with amyloid proteins and amyloid-like proteins, such as Alzheimer’s disease. Precursors for the preparation of the compounds according to the present invention are also provided.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.HPLC of Formula: C3HBr2NS. In my other articles, you can also check out more blogs about 4175-77-3

Reference：
Thiazole | C3H1273NS – PubChem,
Thiazole | chemical compound | Britannica

In an article, published in an article, once mentioned the application of 39893-80-6, Name is 4-(3,4-Dichlorophenyl)thiazol-2-amine,molecular formula is C9H6Cl2N2S, is a conventional compound. this article was the specific content is as follows.HPLC of Formula: C9H6Cl2N2S

Different dimeric disulfides, having the basic skeleton of bis[2-amino-4-phenyl-5-thiazolyl] disulfides were synthesized in a straightforward manner from acetophenones. 2-Amino-4-phenyl-1,3-thiazoles were prepared by the reaction of thiourea with substituted acetophenones in the presence of iodine which were then converted to the title compounds. All the compounds were subjected to preliminary evaluation for their biological activity against Gram positive and Gram negative bacteria. Some of the assayed compounds showed marked activity against Bacillus cereus and Pseudomonas aeruginosa.

Do you like my blog? If you like, you can also browse other articles about this kind. HPLC of Formula: C9H6Cl2N2S. Thanks for taking the time to read the blog about 39893-80-6

Reference：
Thiazole | C3H4663NS – PubChem,
Thiazole | chemical compound | Britannica

Related Products of 39893-80-6. Let’s face it, organic chemistry can seem difficult to learn. Especially from a beginner’s point of view. Like 39893-80-6, Name is 4-(3,4-Dichlorophenyl)thiazol-2-amine. In a document type is Patent, introducing its new discovery.

The disclosed modulators of Rb:Raf-1 interactions are potent, selective disruptors of Rb:Raf-1 binding, with IC50 values ranging from 80 nM to 500 nM. Further, these compounds are surprisingly effective in inhibiting a wide variety of cancer cells, including osteosarcoma, epithelial lung carcinoma, non small cell lung carcinoma, three different pancreatic cancer cell lines, two different glioblastoma cell lines, metastatic breast cancer, melanoma, and prostate cancer. Moreover, the disclosed compounds effectively disrupt angiogenesis and significantly inhibited tumors in nude mice derived from human epithelial lung carcinoma tumors. Accordingly, the disclosed compounds, pharmaceutical compositions comprising the compounds, methods of inhibiting cell proliferation, methods of treating subjects with cancer, and methods of preparing the disclosed compounds are provided.

If you are interested in 39893-80-6, you can contact me at any time and look forward to more communication.Related Products of 39893-80-6

Reference：
Thiazole | C3H4652NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 566169-93-5, Name is 2-(4-(Methylamino)phenyl)benzo[d]thiazol-6-ol, molecular formula is C14H12N2OS. In a Patent，once mentioned of 566169-93-5, Safety of 2-(4-(Methylamino)phenyl)benzo[d]thiazol-6-ol

Various compounds, compositions, and methods for binding to beta-amyloid plaque and norepinephrine transporters are presented. Especially preferred compounds include those with a PET-detectable label.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.Safety of 2-(4-(Methylamino)phenyl)benzo[d]thiazol-6-ol, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 566169-93-5, in my other articles.

Reference：
Thiazole | C3H418NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 16582-59-5, Name is 2-Amino-4,6-dichlorobenzothiazole, molecular formula is C7H4Cl2N2S. In a Patent，once mentioned of 16582-59-5, Application In Synthesis of 2-Amino-4,6-dichlorobenzothiazole

Substituted benzothiazoles I and their salts STR1 used as herbicides and for the desiccation/abscission of plants.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.Application In Synthesis of 2-Amino-4,6-dichlorobenzothiazole, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 16582-59-5, in my other articles.

Reference：
Thiazole | C3H1893NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 4845-58-3, Name is 6-Nitrobenzo[d]thiazole-2(3H)-thione, molecular formula is C7H4N2O2S2. In a Article，once mentioned of 4845-58-3, HPLC of Formula: C7H4N2O2S2

Small-conductance (KCa2.1-2.3) and intermediate-conductance (KCa3.1) calcium-activated K+ channels are critically involved in modulating calcium-signaling cascades and membrane potential in both excitable and nonexcitable cells. Activators of these channels constitute useful pharmacological tools and potential new drugs for the treatment of ataxia, epilepsy, and hypertension. Here, we used the neuroprotectant riluzole as a template for the design of KCa2/3 channel activators that are potent enough for in vivo studies. Of a library of 41 benzothiazoles, we identified 2 compounds, anthra[2,1-d] thiazol-2-ylamine (SKA-20) and naphtho[1,2-d] thiazol-2-ylamine (SKA-31), which are 10 to 20 times more potent than riluzole and activate KCa2.1 with EC50 of 430 nM and 2.9 muM, KCa2.2 with an EC50 value of 1.9 muM, KCa2.3 with EC50 values of 1.2 and 2.9 muM, and KCa3.1 with EC50 values of 115 and 260 nM. Likewise, SKA-20 and SKA-31 activated native KCa2.3 and KCa3.1 channels in murine endothelial cells, and the more “drug-like” SKA-31 (half-life of 12 h) potentiated endothelium-derived hyperpolarizing factor-mediated dilations of carotid arteries from KCa3.1(+/+) mice but not from KCa3.1(-/-) mice. Administration of 10 and 30 mg/kg SKA-31 lowered mean arterial blood pressure by 4 and 6 mm Hg in normotensive mice and by 12 mm Hg in angiotensin-II-induced hypertension. These effects were absent in KCa3.1-deficient mice. In conclusion, with SKA-31, we have designed a new pharmacological tool to define the functional role of the KCa2/3 channel activation in vivo. The blood pressure-lowering effect of SKA-31 suggests KCa3.1 channel activation as a new therapeutic principle for the treatment of hypertension. Copyright

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.HPLC of Formula: C7H4N2O2S2, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 4845-58-3, in my other articles.

Reference：
Thiazole | C3H7356NS – PubChem,
Thiazole | chemical compound | Britannica