Tag: M.W:200-300

Application of 16112-21-3, An article , which mentions 16112-21-3, molecular formula is C14H11NS. The compound – 2-(4-Methylphenyl)benzothiazole played an important role in people’s production and life.

The invention provides a 2 – substituted benzo thiazole compound of the novel preparation method, relates to the field of organic synthetic chemistry. The present invention provides a novel preparation method of the catalyst, in the presence of oxidizing agent and additive, using toluene or derivatives thereof free radical reaction process with the amino thiophenol one-step reaction to produce 2 – substituted benzo thiazole compound. As a non-limiting example, the proposal of the invention, the beneficial effect is that: the invention for the first time made by free radical method so that the toluene or its derivatives and the amino thiophenol by constructing C – S key and C – N key a step coupling generating 2 – substituted benzo thiazole, with high efficiency, simple, environment friendly, easy availability of raw materials, the purity of the product and the like, has a good application value and research prospect. (by machine translation)

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 16112-21-3, help many people in the next few years., Application of 16112-21-3

Reference：
Thiazole | C3H646NS – PubChem,
Thiazole | chemical compound | Britannica

768-11-6, Name is 5-Bromobenzothiazole, molecular formula is C7H4BrNS, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 768-11-6, Safety of 5-Bromobenzothiazole

The present invention relates to novel spirobicyclic analogues of Formula (I) wherein the variables have the meaning defined in the claims. The compounds according to the present invention are useful as PRMT5 inhibitors. The invention further relates to pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Safety of 5-Bromobenzothiazole. In my other articles, you can also check out more blogs about 768-11-6

Reference：
Thiazole | C3H6111NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.14070-51-0, Name is 2-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide, molecular formula is C7H4ClNO3S. In a Article，once mentioned of 14070-51-0, Recommanded Product: 14070-51-0

NiCo2S4 is considered as a promising candidate for high-performance supercapacitors as it stores energy through fast surface redox reactions. However, it suffers from severe aggregation which deteriorates their stability. Herein, uniformly distributed NiCo2S4 nanotubes anchored on a 3D ultrathin nitrogen (N)-doped graphene framework (NGF) are obtained via a facile hydrothermal method, followed by a sulfurization process. The NGF composed of conductive three-dimensional graphene scaffolds can not only ensure even distribution of NiCo2S4 but also facilitate electron transport. Meanwhile, NiCo2S4 nanotubes with hollow structures can shorten the diffusion pathway of electrolyte ions. The strong synergistic effect between NiCo2S4 nanotubes and the NGF substrate helps to obtain satisfactory electrochemical properties. Accordingly, the as-prepared NiCo2S4/NGF composite exhibits a specific capacitance of 1240 F g-1 (558 C g-1) at 1 A g-1, almost 2-fold of its counterpart NiCo2S4 (688.9 F g-1/310 C g-1). Moreover, the corresponding hybrid energy device (NiCo2S4/NGF\AC) demonstrates a superb energy density of 36.8 Wh kg-1 and outstanding cycling stability. This admirable design of the NiCo2S4/NGF composite holds great promise as an electrode material in supercapacitor application.

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 14070-51-0 is helpful to your research., Recommanded Product: 14070-51-0

Reference：
Thiazole | C3H3105NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.72850-52-3, Name is Ethyl 2-chloro-4-(trifluoromethyl)thiazole-5-carboxylate, molecular formula is C7H5ClF3NO2S. In a Patent，once mentioned of 72850-52-3, HPLC of Formula: C7H5ClF3NO2S

2-chloro-4,5-disubstituted-thiazoles have been found to be effective in reducing herbicidal injury to sorghum plants due to the application thereto of acetanilide and thiocarbamate herbicides.

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 72850-52-3 is helpful to your research., HPLC of Formula: C7H5ClF3NO2S

Reference：
Thiazole | C3H8064NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 72850-52-3, Name is Ethyl 2-chloro-4-(trifluoromethyl)thiazole-5-carboxylate, molecular formula is C7H5ClF3NO2S. In a Patent，once mentioned of 72850-52-3, Formula: C7H5ClF3NO2S

Compounds of formula (I) wherein the substituents are as defined in claim 1, are suitable for use as herbicides. Also claimed is a process for the preparation of compounds of the formula I, wherein m is 2 and n is 1, and the other substituents are defined as in claim 1, formula (Ia) by reacting a compound of the formula Ia in a single step or stepwise in succession with compounds of the formula R5-X and/or R6-X, wherein R5 and R6 are as defined in claim 1, and X is a leaving group, and a process for the preparation of compounds of the formula I, wherein R6 is C1­-C10alkyl or halogen, m is 2 and n is 1, and the other substituents are defined as in claim 1, formula (Ib) by reacting a compound of the formula 1b with a compound of the formula R5-X, wherein R5 is as defined in claim 1, and X is a leaving group, and a process for the preparation of compounds of the formula I, wherein R5 is chlorine, bromine or iodine, m is 1 or 2, and n is 1, and the other substituents are defined as in claim 1, formula (Ic) by reacting a compound of the formula le with an N- halosuccinimide and an oxidising agent.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.Formula: C7H5ClF3NO2S, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 72850-52-3, in my other articles.

Reference：
Thiazole | C3H8059NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.153719-23-4, Name is N-(3-((2-Chlorothiazol-5-yl)methyl)-5-methyl-1,3,5-oxadiazinan-4-ylidene)nitramide, molecular formula is C8H10ClN5O3S. In a Article，once mentioned of 153719-23-4, COA of Formula: C8H10ClN5O3S

A very sensitive ultrahigh performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method was developed and validated for the quantitation of the most common neonicotinoids (thiamethoxam, clothianidin, imidacloprid, acetamiprid, and thiacloprid) at trace levels in milk. Using fast and selective liquid-liquid extraction (LLE) starting from 0.5 mL of milk, lowest limits of quantitation (LLOQ) equal or lower than 10 pg/mL for all analytes were achieved. Precision and accuracy were evaluated at four different concentrations (5, 10, 500, and 10000 pg/mL) and ranged between 2 and 16% (RSD) and 77-125%, respectively. Extraction recoveries and matrix effects ranged between 64 and 76% and 88-98%, respectively. The method was applied to measure neonicotinoid levels in a series of conventional and organic Swiss milks as well as in human breast milk and commercial powdered milk. More than 90% of the samples tested positive for at least one neonicotinoid. However, all animal samples were far below the maximum residue limits authorized for human consumption with average total neonicotinoid levels of 16.1 ± 13.1 pg/mL. Human breast milks and powdered milks contained similar amounts of neonicotinoids. Taken together, our results demonstrate the high prevalence of neonicotinoids in milk from all origins, albeit at levels considered to be safe for human consumption.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.COA of Formula: C8H10ClN5O3S, you can also check out more blogs about153719-23-4

Reference：
Thiazole | C3H8953NS – PubChem,
Thiazole | chemical compound | Britannica

Related Products of 4175-77-3, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 4175-77-3, C3HBr2NS. A document type is Article, introducing its new discovery.

Through a structure-guided rational drug design approach, we have discovered a highly selective inhibitor compound 40 (JSH-150), which exhibited an IC50 of 1 nM against CDK9 kinase in the biochemical assay and achieved around 300?10000-fold selectivity over other CDK kinase family members. In addition, it also displayed high selectivity over other 468 kinases/mutants (KINOMEscan S score(1) = 0.01). Compound 40 displayed potent antiproliferative effects against melanoma, neuroblastoma, hepatoma, colon cancer, lung cancer as well as leukemia cell lines. It could dose-dependently inhibit the phosphorylation of RNA Pol II, suppress the expression of MCL-1 and c-Myc, arrest the cell cycle and induce the apoptosis in the leukemia cells. In the MV4-11 cell-inoculated xenograft mouse model, 10 mg/kg dosage of 40 could almost completely suppress the tumor progression. The high selectivity and good in vivo PK/PD profile suggested that 40 would be a good pharmacological tool to study CDK9-mediated physiology and pathology as well as a potential drug candidate for leukemia and other cancers.

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Reference：
Thiazole | C3H1250NS – PubChem,
Thiazole | chemical compound | Britannica

In an article, published in an article, once mentioned the application of 768-11-6, Name is 5-Bromobenzothiazole,molecular formula is C7H4BrNS, is a conventional compound. this article was the specific content is as follows.Recommanded Product: 5-Bromobenzothiazole

Benzothiazoles undergo regioselective C2-H functionalization with triphenylphosphine to form thiazol-2-yl-triphenylphosphonium salts, and these phosphonium salts react with a wide range of O- A nd N-centered nucleophiles to give the corresponding ethers, amines, and C-N biaryls. The reactions proceed under mild conditions and allow for the recovery of triphenylphosphine at the end of the sequence. In the presence of hydroxide, phosphonium salts undergo disproportionation, resulting in the reduction of the benzothiazole, which is useful for specific C2 deuteration of benzothiazoles.

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Reference：
Thiazole | C3H6145NS – PubChem,
Thiazole | chemical compound | Britannica

Synthetic Route of 50850-93-6, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 50850-93-6, C10H10N2O2S. A document type is Article, introducing its new discovery.

Rational design, synthesis, and SAR studies of a novel class of benzothiazole based inhibitors of p38alpha MAP kinase are described. The issue of metabolic instability associated with vicinal phenyl, benzo[d]thiazol-6-yl oxazoles/imidazoles was addressed by the replacement of the central oxazole or imidazole ring with an aminopyrazole system. The proposed binding mode of this new class of p38alpha inhibitors was confirmed by X-ray crystallographic studies of a representative inhibitor (6a) bound to the p38alpha enzyme.

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Reference：
Thiazole | C3H10654NS – PubChem,
Thiazole | chemical compound | Britannica

Application of 66947-92-0. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 66947-92-0, Name is Methyl 2-amino-1,3-benzothiazole-6-carboxylate

This invention relates to novel analogs of the DNA-alkylating agent CC-1065 and to their conjugates. Furthermore this invention concerns intermediates for the preparation of said agents and conjugates. The conjugates are designed to release their (multiple) payload after one or more activation steps and/or at a rate and time span controlled by the conjugate in order to selectively deliver and/or controllably release one or more of said DNA alkylating agents. The agents, conjugates, and intermediates can be used to treat an illness that is characterized by undesired (cell) proliferation. As an example, the agents and the conjugates of this invention may be used to treat a tumor.

If you are hungry for even more, make sure to check my other article about 66947-92-0. Application of 66947-92-0

Reference：
Thiazole | C3H8376NS – PubChem,
Thiazole | chemical compound | Britannica