Tag: M.W:200-300

In an article, published in an article, once mentioned the application of 5331-91-9, Name is 5-Chlorobenzo[d]thiazole-2(3H)-thione,molecular formula is C7H4ClNS2, is a conventional compound. this article was the specific content is as follows.Safety of 5-Chlorobenzo[d]thiazole-2(3H)-thione

A new class of novel thiazole-(benz)azole derivatives was synthesized to investigate their anticancer activity. The structure of the compounds was confirmed by IR, 1H-NMR, and MS spectral data and elemental analyses. Anticancer effect of the compounds was evaluated against A549 and C6 tumor cell lines. MTT, analysis of DNA synthesis, acridine orange/ethidium bromide staining method and analysis of caspase-3 activation assays were performed for anticancer activity investigations. Compounds 6f and 6g, which carry 5-chloro and 5-methylbenzimidazole groups showed significant anticancer activity. Potential of these compounds to direct tumor cells to apoptotic pathway, which is a precondition of anticancer action, was also observed.

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Reference：
Thiazole | C3H6371NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 80945-86-4, Name is 6-Bromo-2-chlorobenzothiazole, molecular formula is C7H3BrClNS. In a Patent，once mentioned of 80945-86-4, Quality Control of: 6-Bromo-2-chlorobenzothiazole

The present invention relates to novel inhibitors of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders. Processes for preparing these inhibitors are also disclosed.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.Quality Control of: 6-Bromo-2-chlorobenzothiazole, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 80945-86-4, in my other articles.

Reference：
Thiazole | C3H10863NS – PubChem,
Thiazole | chemical compound | Britannica

Electric Literature of 53218-26-1, An article , which mentions 53218-26-1, molecular formula is C7H4BrNS. The compound – 6-Bromobenzo[d]thiazole played an important role in people’s production and life.

An iron-catalyzed arylation or aroylation of benzothiazoles with alcohols and aryl ketones via an in situ cross-trapping strategy has been described. Both the use of an iron catalyst and the ratio of substrates are important for this transformation, and this reaction is sensitive to the electronic effects of the substituents.

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Reference：
Thiazole | C3H6924NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 53218-26-1, Name is 6-Bromobenzo[d]thiazole, molecular formula is C7H4BrNS. In a Article，once mentioned of 53218-26-1, Product Details of 53218-26-1

Herein, a new procedure for the carbonylative acetylation of heterocycles has been developed. In this process, organic peroxide acts as the methyl source. Various heterocycles were transformed into the corresponding methyl heterocyclic ketones in moderate to good yields.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.Product Details of 53218-26-1, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 53218-26-1, in my other articles.

Reference：
Thiazole | C3H6911NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 886361-30-4, Name is Methyl 2-amino-5-(4-fluorophenyl)thiazole-4-carboxylate, molecular formula is C11H9FN2O2S. In a Patent，once mentioned of 886361-30-4, Recommanded Product: 886361-30-4

The invention relates to thiazolidine derivatives of the formula (I) wherein A, B, and R1 are as described in the description, to salts, especially pharmaceutically acceptable salts, of such compounds and to their use as medicaments, especially as orexin receptor antagonists

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Recommanded Product: 886361-30-4. In my other articles, you can also check out more blogs about 886361-30-4

Reference：
Thiazole | C3H8405NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.78485-37-7, Name is Ethyl 2-chloro-6-benzothiazolecarboxylate, molecular formula is C10H8ClNO2S. In a Patent，once mentioned of 78485-37-7, Application In Synthesis of Ethyl 2-chloro-6-benzothiazolecarboxylate

Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions of compounds of formula (I), methods for using such compounds and compositions, and a process for preparing the compounds.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Application In Synthesis of Ethyl 2-chloro-6-benzothiazolecarboxylate, you can also check out more blogs about78485-37-7

Reference：
Thiazole | C3H8085NS – PubChem,
Thiazole | chemical compound | Britannica

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 4845-58-3, Name is 6-Nitrobenzo[d]thiazole-2(3H)-thione, Recommanded Product: 4845-58-3.

Bone resorption by osteoclasts is dependent on H+ transport into the external resorption lacunae, generating an acidic microenvironment in which bone mineral dissolution and matrix degradation occur. A vacuolar H+-ATPase is responsible for osteoclast H+ secretion. Here, we describe novel vacuolar H+-ATPase inhibitors that inhibit bone resorption in vitro. Several agents inhibited 45Ca release from mouse calvariae, 3H-proline release from bone particles by chicken osteoclast-like cells, and resorption pit formation by murine osteoclasts on dentine slices. One compound, a 2-sulfinylbenzothiazole (XS238), is significantly more potent than previously reported vacuolar H+-ATPase inhibitors, exhibiting an IC50 of 5 muM in the 45Ca release assay, an IC50 of 1 muM in the 3H-proline release assay, and an IC50 of 100 nM in the resorption pit assay. The potent H+-ATPase inhibitors described may have value in treating osteoporosis and other bone diseases.

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Reference：
Thiazole | C3H7376NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.16112-21-3, Name is 2-(4-Methylphenyl)benzothiazole, molecular formula is C14H11NS. In a Patent，once mentioned of 16112-21-3, Product Details of 16112-21-3

The invention discloses a in the aqueous phase and microwave […] thioamide compound synthesis of benzothiazole of the method, in the aqueous phase under microwave conditions adding benzo thioamide compound under alkaline conditions […] into benzothiazole reaction, invention an environment-friendly, the operation is simple, cheap and safe, efficient process for the preparation of thiazole. Compared with the prior art, this method not only can be applied to a large number of functional groups, the productive rate is high, few by-products, and the operation is simple, safe, low cost, environmental protection; . (by machine translation)

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Reference：
Thiazole | C3H651NS – PubChem,
Thiazole | chemical compound | Britannica

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 199475-45-1, Name is 5-Bromobenzo[d]thiazol-2(3H)-one, Quality Control of: 5-Bromobenzo[d]thiazol-2(3H)-one.

The present invention provides compounds of formula (I), in which y, m, n, R 1 , R 2 and Q are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them and their use in therapy.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Quality Control of: 5-Bromobenzo[d]thiazol-2(3H)-one. In my other articles, you can also check out more blogs about 199475-45-1

Reference：
Thiazole | C3H6094NS – PubChem,
Thiazole | chemical compound | Britannica

Application of 17969-20-9. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 17969-20-9, Name is 2-(2-(4-Chlorophenyl)thiazol-4-yl)acetic acid

A method for stabilizing an arylcarboxylic acid, which comprises adding a heterocyclic base to the arylcarboxylic acid or a pharmacologically acceptable salt thereof, a stabilizer thereof and an aqueous solution containing a stabilized arylcarboxylic acid. According to the stabilization method of the present invention, arylcarboxylic acid and pharmacologically acceptable salts thereof, particularly pranoprofen, can be stabilized at every temperature range, particularly at lower temperatures, thereby making the production of an aqueous solution to be used as an eye drop, nasal drop, ear drop and the like possible.

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Reference：
Thiazole | C3H396NS – PubChem,
Thiazole | chemical compound | Britannica