Tag: M.W:200-300

3855-95-6, Name is 2-Chloro-6-benzothiazolecarboxylic acid, molecular formula is C8H4ClNO2S, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 3855-95-6, Recommanded Product: 3855-95-6

Compounds useful for affinity chromatography as presented, more particularly for use in affinity chromatography to purify serum albumin, especially human serum albumin (HSA) and fusion proteins thereof. Methods for extending the half-life of therapeutic agents are also presented, particularly therapeutic peptide agents and small molecules, such as by conjugation of compounds described herein to the therapeutic peptide or small molecule, which, upon administration, binds to HSA, thereby providing a prolonged release of the therapeutic agent.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Recommanded Product: 3855-95-6. In my other articles, you can also check out more blogs about 3855-95-6

Reference：
Thiazole | C3H3042NS – PubChem,
Thiazole | chemical compound | Britannica

Synthetic Route of 1024583-33-2. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 1024583-33-2, Name is Methyl 2-bromobenzo[d]thiazole-6-carboxylate

A series of small molecule compounds interfering with the binding process of VEGF and NRP1 has been identified and further optimized. Full synthetic details as well as SAR are reported which demonstrate that expeditious MCC-based syntheses may lead to valuable molecules addressing challenging targets such as protein-protein interactions. Preliminary functional assay data confirm that these compounds may be further developed toward drug candidates.

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Reference：
Thiazole | C3H8443NS – PubChem,
Thiazole | chemical compound | Britannica

Reference of 848841-68-9. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 848841-68-9, Name is 4-(4-Chlorothiazol-2-yl)morpholine

The present invention relates to compounds of Formula (I), pharmaceutical compositions thereof, and use thereof as corticotropin releasing factor 1 (CRF1) receptor antagonists in the treatment of psychiatric and neuroendocrine disorders, neurological diseases, and metabolic syndrome.

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Reference：
Thiazole | C3H4687NS – PubChem,
Thiazole | chemical compound | Britannica

In an article, published in an article, once mentioned the application of 499770-85-3, Name is 6-(Bromomethyl)benzo[d]thiazole,molecular formula is C8H6BrNS, is a conventional compound. this article was the specific content is as follows.Recommanded Product: 499770-85-3

Compounds having the formula I wherein A, m and R1 are herein defined are Hepatitis C virus polymerase inhibitors. Also disclosed are compositions and methods for treating diseases mediated by HCV and for inhibiting hepatitis replication. Also disclosed are processes for making the compounds and synthetic intermediates used in the process

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Reference：
Thiazole | C3H6672NS – PubChem,
Thiazole | chemical compound | Britannica

Application of 869973-63-7, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 869973-63-7, C11H9NO2S. A document type is Patent, introducing its new discovery.

The present invention relates to a series of substituted compounds having the general formula (I), including their stereoisomers and/or their pharmaceutically acceptable salts. (I) Wherein A, m, R1s R2, R3, R4 are as defined herein. This invention also relates to methods of making these compounds including intermediates. The compounds of this invention are effective at the kappa (k) opioid receptor (KOR) site. Therefore, the compounds of this invention are useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of central nervous system disorders (CNS), including but not limited to acute and chronic pain, and associated disorders, particularly functioning peripherally at the CNS

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Reference：
Thiazole | C3H251NS – PubChem,
Thiazole | chemical compound | Britannica

Reference of 2941-56-2, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 2941-56-2, Name is 2-Bromo-5-chlorobenzo[d]thiazole, molecular formula is C7H3BrClNS. In a Article，once mentioned of 2941-56-2

A series of chiral, (S)-proline-alpha-methylpyrrolidine-5,5-trans-lactam serine protease inhibitors has been developed as antivirals of human cytomegalovirus (HCMV). The SAR of the functionality on the proline nitrogen has shown that derivatives of para-substituted phenyl ureas > para-substituted phenyl sulfonamides > para-substituted phenyl carboxamide for activity against HCMV deltaAla protease, producing para-substituted phenyl ureas with single figure nM potency (Ki) against the viral enzyme. The SAR of the functionality on the lactam nitrogen has defined the steric and electronic requirements for high human plasma stability while retaining good activity against HCMV protease. The combination of high potency against HCMV deltaAla protease and high human plasma stability has produced compounds with significant in vitro antiviral activity against human cytomegalovirus with the 6-hydroxymethyl benzothiazole derivative 72 being equivalent in potency to ganciclovir. The parent benzothiazole 56 had good pharmacokinetics in dogs with 29% bioavailability and good brain and ocular penetration in guinea pigs.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 2941-56-2 is helpful to your research., Reference of 2941-56-2

Reference：
Thiazole | C3H2493NS – PubChem,
Thiazole | chemical compound | Britannica

1160789-91-2, Name is 5-Bromo-6-fluorobenzo[d]thiazol-2-amine, molecular formula is C7H4BrFN2S, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 1160789-91-2, COA of Formula: C7H4BrFN2S

The present invention relates to novel compounds (benzothiazolopyrazoles and thiazolopyridin-pyrazoles) useful for binding and imaging amyloid deposits and their use in detecting or treating Alzheimer”s disease and amyloidosis.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.COA of Formula: C7H4BrFN2S. In my other articles, you can also check out more blogs about 1160789-91-2

Reference：
Thiazole | C3H6088NS – PubChem,
Thiazole | chemical compound | Britannica

Synthetic Route of 38923-13-6, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 38923-13-6, C5H4BrNOS. A document type is Article, introducing its new discovery.

MK-4256, a tetrahydro-beta-carboline sstr3 antagonist, was discontinued due to a cardiovascular (CV) adverse effect observed in dogs. Additional investigations revealed that the CV liability (QTc prolongation) was caused by the hERG off-target activity of MK-4256 and was not due to sstr3 antagonism. In this Letter, we describe our extensive SAR effort at the C3 position of the tetrahydro-beta-carboline structure. This effort resulted in identification of 5-fluoro-pyridin-2-yl as the optimal substituent on the imidazole ring to balance sstr3 activity and the hERG off-target liability.

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Reference：
Thiazole | C3H2401NS – PubChem,
Thiazole | chemical compound | Britannica

In an article, published in an article, once mentioned the application of 38923-13-6, Name is 2-Bromo-1-(thiazol-4-yl)ethanone,molecular formula is C5H4BrNOS, is a conventional compound. this article was the specific content is as follows.name: 2-Bromo-1-(thiazol-4-yl)ethanone

Substituted thiazoles, oxazoles and 2-hydroxy morpholine compounds useful in the treatment of diabetes mellitus and obesity are described.

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Reference：
Thiazole | C3H2400NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.850429-60-6, Name is Methyl 2-amino-5-bromothiazole-4-carboxylate, molecular formula is C5H5BrN2O2S. In a Patent，once mentioned of 850429-60-6, Formula: C5H5BrN2O2S

Nitrogen-containing heterocyclic compounds represented by the following Formula (1) are provided. The compounds or salts thereof have a strong EP1 antagonistic activity when they are administered to a human or an animal, and they are useful as an effective component of a pharmaceutical agent for prophylaxis and/or treatment of an overactive bladder, for example. Furthermore, they are useful as an effective component of a pharmaceutical agent for the prophylaxis and/or treatment of symptoms including frequent urination, urinary urgency and urinary incontinence

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 850429-60-6 is helpful to your research., Formula: C5H5BrN2O2S

Reference：
Thiazole | C3H8419NS – PubChem,
Thiazole | chemical compound | Britannica