Tag: M.W:200-300

564443-27-2, Name is 6-(Trifluoromethyl)imidazo[2,1-b]thiazole-5-carbaldehyde, molecular formula is C7H3F3N2OS, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 564443-27-2, Computed Properties of C7H3F3N2OS

The invention relates to novel azetidine compounds of formula (I), wherein R1, R2, and X are as described in the description and their use as orexin receptor antagonists.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Computed Properties of C7H3F3N2OS. In my other articles, you can also check out more blogs about 564443-27-2

Reference：
Thiazole | C3H6752NS – PubChem,
Thiazole | chemical compound | Britannica

1024583-33-2, Name is Methyl 2-bromobenzo[d]thiazole-6-carboxylate, molecular formula is C9H6BrNO2S, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 1024583-33-2, Application In Synthesis of Methyl 2-bromobenzo[d]thiazole-6-carboxylate

Substituted bromopyridines undergo facile nucleophilic substitution with lithioacetonitrile under mild conditions to afford the corresponding cyanomethylated products.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application In Synthesis of Methyl 2-bromobenzo[d]thiazole-6-carboxylate. In my other articles, you can also check out more blogs about 1024583-33-2

Reference：
Thiazole | C3H8441NS – PubChem,
Thiazole | chemical compound | Britannica

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 2941-56-2, Name is 2-Bromo-5-chlorobenzo[d]thiazole, name: 2-Bromo-5-chlorobenzo[d]thiazole.

A series of cis-1,2-diaminocyclohexane derivatives were synthesized with the aim of optimizing previously disclosed factor Xa (fXa) inhibitors. The exploration of 5-6 fused rings as alternative S1 moieties resulted in two compounds which demonstrated improved solubility and reduced food effect compared to the clinical candidate, compound A. Herein, we describe the synthesis and structure-activity relationship (SAR), together with the physicochemical properties and pharmacokinetic (PK) profiles of some prospective compounds.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.name: 2-Bromo-5-chlorobenzo[d]thiazole. In my other articles, you can also check out more blogs about 2941-56-2

Reference：
Thiazole | C3H2492NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 112146-10-8, Name is 4-Bromo-2-methylbenzo[d]thiazole, molecular formula is C8H6BrNS. In a Article，once mentioned of 112146-10-8, SDS of cas: 112146-10-8

Various 2-aryl-6-bromo-1,3-benzothiazoles were regioselectively afforded in good yields by the reaction of arylaldehydes and 2-aminothiophenol with phenyltrimethylammonium tribromide in the presence of a catalytic amount of SbBr3 in CH2Cl2 at room temperature.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.SDS of cas: 112146-10-8, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 112146-10-8, in my other articles.

Reference：
Thiazole | C3H5116NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.136411-21-7, Name is 5-Bromo-4-(trifluoromethyl)thiazol-2-amine, molecular formula is C4H2BrF3N2S. In a Patent，once mentioned of 136411-21-7, Computed Properties of C4H2BrF3N2S

A medicament having inhibitory activity against NF- kappa B activation, which comprises a compound represented by the following general formula (I) or a pharmacologically acceptable salt as an active ingredient: wherein X represents a connecting group, A represents hydrogen atom or acetyl group, E represents an aryl group or a heteroaryl group, and ring X represents an arene or a heteroarene.

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 136411-21-7 is helpful to your research., Computed Properties of C4H2BrF3N2S

Reference：
Thiazole | C3H6072NS – PubChem,
Thiazole | chemical compound | Britannica

Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 71216-20-1, C7H4BrNS2. A document type is Patent, introducing its new discovery., Computed Properties of C7H4BrNS2

The invention belongs to the field of medical and chemical intermediate synthesis, provides a based on 1, 3 – propanedithiol as mercapto source synthesis 2 – oxa (thia) and mercaptobenzothiazole azole compound of preparation method, under protection of inert gas, in dimethyl sulfoxide solvent, the oxa (thia) substituted azole with 1, 3 – propanedithiol in the presence of a alkali 120 – 140 C heating and stirring, reaction 12 – 24 hours later, the reaction is cooled down to room temperature, after the acidification is carried out processing to obtain the product. The invention has the reaction condition is simple, functional group compatibility advantages of better and higher yield; the prepared 2 – mercapto-benzoxazole and 2 – mercaptobenzothiazole compound is an important organic synthetic intermediates, raw material in the chemical industry, pesticide, medicine and other field has a very wide application, has strong practical value and social and economic benefits. (by machine translation)

Interested yet? Keep reading other articles of 71216-20-1!, Computed Properties of C7H4BrNS2

Reference：
Thiazole | C3H6059NS – PubChem,
Thiazole | chemical compound | Britannica

Electric Literature of 944804-88-0. Let’s face it, organic chemistry can seem difficult to learn. Especially from a beginner’s point of view. Like 944804-88-0, Name is tert-Butyl 4-bromothiazol-2-ylcarbamate. In a document type is Patent, introducing its new discovery.

The present invention relates to an inhibitor of cyclin-dependent kinase CDK9, having a structure of formula (I). The present invention also provides a method of treating a cancer of a precancerous condition related to CDK9 activity with the inhibitor and a use of the same.

If you are interested in 944804-88-0, you can contact me at any time and look forward to more communication.Electric Literature of 944804-88-0

Reference：
Thiazole | C3H9088NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 3855-95-6, Name is 2-Chloro-6-benzothiazolecarboxylic acid, molecular formula is C8H4ClNO2S. In a Patent£¬once mentioned of 3855-95-6, Recommanded Product: 3855-95-6

A compound of Formula (1) and salts thereof: wherein: R1 and R2 are independently H or optionally substituted alkyl; X and Y are independently CO2H or COSH; Q and T are independent substituents; a + n is 0 to 4; b + m is 0 to 4; and n + m are at least 1; also ink-jet compositions, processes and printed material.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Recommanded Product: 3855-95-6. In my other articles, you can also check out more blogs about 3855-95-6

Reference£º
Thiazole | C3H3043NS – PubChem,
Thiazole | chemical compound | Britannica

Synthetic Route of 564443-27-2. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 564443-27-2, Name is 6-(Trifluoromethyl)imidazo[2,1-b]thiazole-5-carbaldehyde

The pharmacology of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel has attracted significant interest in recent years with the aim to search for rational new therapies for diseases caused by CFTR malfunction. Mutations that abolish the function of CFTR cause the life-threatening genetic disease cystic fibrosis (CF). The most common cause of CF is the deletion of phenylalanine 508 (DeltaF508) in the CFTR chloride channel. Felodipine, nifedipine, and other antihypertensive 1,4-dihydropyridines (1,4-DHPs) that block L-type Ca2+ channels are also effective potentiators of CFTR gating, able to correct the defective activity of DeltaF508 and other CFTR mutants (Mol. Pharmacol. 2005, 68, 1736). For this purpose, we evaluated the ability of the previously and newly synthesized 4-imidazo[2,1-b]thiazoles-1,4-dihydropyridines without vascular activity and inotropic and/or chronotropic cardiac effects (J. Med. Chem. 2008, 51, 1592) to enhance the activity of DeltaF508-CFTR. Our studies indicate compounds 17, 18, 20, 21, 38, and 39 as 1,4-DHPs with an interesting profile of activity.

If you are hungry for even more, make sure to check my other article about 564443-27-2. Synthetic Route of 564443-27-2

Reference£º
Thiazole | C3H6750NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 944804-88-0, Name is tert-Butyl 4-bromothiazol-2-ylcarbamate, molecular formula is C8H11BrN2O2S. In a Patent£¬once mentioned of 944804-88-0, SDS of cas: 944804-88-0

A new class of alkylsulfonyl-substituted thiazolide compounds is described. These compounds show strong activity against hepatitis virus.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.SDS of cas: 944804-88-0, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 944804-88-0, in my other articles.

Reference£º
Thiazole | C3H9093NS – PubChem,
Thiazole | chemical compound | Britannica