Tag: M.W:200-300

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 16112-21-3, Name is 2-(4-Methylphenyl)benzothiazole, molecular formula is C14H11NS. In a Article，once mentioned of 16112-21-3, Formula: C14H11NS

Benzothiazole derivatives 1-26 have been synthesized and their in vitro beta-glucuronidase potential has been evaluated. Compounds 4 (IC50 = 8.9 ± 0.25 muM), 5 (IC50 = 36.1 ± 1.80 muM), 8 (IC50 = 8.9 ± 0.38 muM), 13 (IC50 = 19.4 ± 1.00 muM), 16 (IC50 = 4.23 ± 0.054 muM), and 18 (IC 50 = 2.26 ± 0.06 muM) showed beta-glucuronidase activity potent than the standard (d-saccharic acid 1,4-lactone, IC50 = 48.4 ± 1.25 muM). Compound 9 (IC50 = 94.0 ± 4.16 muM) is found to be the least active among the series. All active analogs were also evaluated for cytotoxicity and none of the compounds showed any cytotoxic effect. Furthermore, molecular docking studies were performed using the gold 3.0 program to investigate the binding mode of benzothiazole derivatives. This study identifies a novel class of beta-glucuronidase inhibitors.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.Formula: C14H11NS, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 16112-21-3, in my other articles.

Reference：
Thiazole | C3H750NS – PubChem,
Thiazole | chemical compound | Britannica

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 29182-42-1, Name is Ethyl 2-(benzo[d]thiazol-2-yl)acetate, molecular formula is C11H11NO2S. In a Patent，once mentioned of 29182-42-1, Recommanded Product: 29182-42-1

The present application relates to new coumarin compounds and their uses as fluorescent labels. The compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.Recommanded Product: 29182-42-1, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 29182-42-1, in my other articles.

Reference：
Thiazole | C3H7833NS – PubChem,
Thiazole | chemical compound | Britannica

Related Products of 4845-58-3, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 4845-58-3, Name is 6-Nitrobenzo[d]thiazole-2(3H)-thione, molecular formula is C7H4N2O2S2. In a Patent，once mentioned of 4845-58-3

Disclosed is a novel process for the preparation of 2-amino-6-nitrobenzothiazole which comprises contacting 2-mercapto-6-nitrobenzothiazole with hydrogen peroxide in the presence of ammonia. The reaction is conveniently conducted in an aqueous medium. The mole ratio of hydrogen peroxide to mercaptan is preferably about 4:1 and the reaction is conducted at a temperature of about 50 to 100 C.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 4845-58-3 is helpful to your research., Related Products of 4845-58-3

Reference：
Thiazole | C3H7374NS – PubChem,
Thiazole | chemical compound | Britannica

Related Products of 654070-00-5, An article , which mentions 654070-00-5, molecular formula is C7H4INS. The compound – 6-Iodobenzo[d]thiazole played an important role in people’s production and life.

A series of dipolar and octupolar triphenylamine-derived dyes containing a benzothiazole positioned in the matched or mismatched fashion have been designed and synthesized via palladium-catalyzed Sonogashira cross-coupling reactions. Linear and nonlinear optical properties of the designed molecules were tuned by an additional electron-withdrawing group (EWG) and by changing the relative positions of the donor and acceptor substituents on the heterocyclic ring. This allowed us to examine the effect of positional isomerism and extend the structure-property relationships useful in the engineering of novel heteroaromatic-based systems with enhanced two-photon absorption (TPA). The TPA cross-sections (deltaTPA) in the target compounds dramatically increased with the branching of the triphenylamine core and with the strength of the auxiliary acceptor. In addition, a change from the commonly used polarity in push-pull benzothiazoles to a reverse one has been revealed as a particularly useful strategy (regioisomeric control) for enhancing TPA cross-sections and shifting the absorption and emission maxima to longer wavelengths. The maximum TPA cross-sections of the star-shaped three-branched triphenylamines are ?500-2300 GM in the near-infrared region (740-810 nm); thereby the molecular weight normalized deltaTPA/MW values of the best performing dyes within the series (2.0-2.4 GM?g-1?mol) are comparable to those of the most efficient TPA chromophores reported to date. The large TPA cross-sections combined with high emission quantum yields and large Stokes shifts make these compounds excellent candidates for various TPA applications, including two-photon fluorescence microscopy.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 654070-00-5, help many people in the next few years., Related Products of 654070-00-5

Reference：
Thiazole | C3H7112NS – PubChem,
Thiazole | chemical compound | Britannica

5331-91-9, Name is 5-Chlorobenzo[d]thiazole-2(3H)-thione, molecular formula is C7H4ClNS2, belongs to thiazole compound, is a common compound. In a patnet, once mentioned the new application about 5331-91-9, name: 5-Chlorobenzo[d]thiazole-2(3H)-thione

The biocidal activity of some benzothiazoles, arylaminomalonates, and their phosphorylated derivatives against iron-oxidizing bacteria of the genus Siderococcus.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.name: 5-Chlorobenzo[d]thiazole-2(3H)-thione. In my other articles, you can also check out more blogs about 5331-91-9

Reference：
Thiazole | C3H6291NS – PubChem,
Thiazole | chemical compound | Britannica

Synthetic Route of 4175-78-4, Chemistry can be defined as the study of matter and the changes it undergoes. You’ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology.4175-78-4, Name is 2,5-Dibromothiazole, molecular formula is C3HBr2NS. In a patent, introducing its new discovery.

We demonstrate that metal-catalyzed enantioselective benzylation reactions of allylic electrophiles can occur directly from aryl acetic acids. The reaction proceeds via a pathway in which decarboxylation is the terminal event, occurring after stereoselective carbon-carbon bond formation. This mechanistic feature enables enantioselective benzylation without the generation of a highly basic nucleophile. Thus, the process has broad functional group compatibility that would not be possible employing established protocols.

If you are interested in 4175-78-4, you can contact me at any time and look forward to more communication.Synthetic Route of 4175-78-4

Reference：
Thiazole | C3H1698NS – PubChem,
Thiazole | chemical compound | Britannica

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.78502-79-1, Name is 2-(Bromomethyl)-4-phenylthiazole, molecular formula is C10H8BrNS. In a Article，once mentioned of 78502-79-1, COA of Formula: C10H8BrNS

A series of benzotriazole phenyldifluoromethylphosphonic acids were found to be potent PTP-1B inhibitors. Molecular modeling on the X-ray crystal structure of the lead structure led to the design of potent PTP-1B inhibitors that show moderate selectivity against TC-PTP, a very closely related protein tyrosine phosphatase.

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 78502-79-1 is helpful to your research., COA of Formula: C10H8BrNS

Reference：
Thiazole | C3H971NS – PubChem,
Thiazole | chemical compound | Britannica

Application of 2103-99-3, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 2103-99-3, Name is 4-(4-Chlorophenyl)thiazol-2-amine, molecular formula is C9H7ClN2S. In a Article，once mentioned of 2103-99-3

Condensation of 2-aminothiazole and its derivatives with vic-hydroxyaldehydes gives Schiff bases which form complexes of the type ML2 with bivalent transition metals.The ligand molecule both N and S donor sites and coordination through any one atom is possible.The elemental analysis suggests 1:2 stoichiometry, magnetic susceptibility and electronic spectral data are in favour of octahedral structure for CoII, NiII and CuII complexes.Infrared spectral data indicate bonding through oxygen atom of the hydroxyl group and a possibility of coordination through nitrogen atom, each of the ligand molecule.Complexes are found to be of nonelectrolytic nature.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 2103-99-3 is helpful to your research., Application of 2103-99-3

Reference：
Thiazole | C3H10225NS – PubChem,
Thiazole | chemical compound | Britannica

In an article, published in an article, once mentioned the application of 40003-41-6, Name is 2-Bromo-4-methylthiazole-5-carboxylic acid,molecular formula is C5H4BrNO2S, is a conventional compound. this article was the specific content is as follows.category: thiazole

The invention concerns novel substituted pyrazolo- and triazolo-pyrimidine compounds of formula (I) having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention further concerns pharmaceutical compositions comprising these compounds and the compounds for use in the treatment of respiratory syncytial virus infection.

Do you like my blog? If you like, you can also browse other articles about this kind. category: thiazole. Thanks for taking the time to read the blog about 40003-41-6

Reference：
Thiazole | C3H2458NS – PubChem,
Thiazole | chemical compound | Britannica

Synthetic Route of 566169-93-5, Chemistry can be defined as the study of matter and the changes it undergoes. You’ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology.566169-93-5, Name is 2-(4-(Methylamino)phenyl)benzo[d]thiazol-6-ol, molecular formula is C14H12N2OS. In a patent, introducing its new discovery.

Atherosclerosis is characterized by the accumulation of oxidized lipids in the artery wall, which triggers an inflammatory response. Oxidized low-density lipoprotein (ox-LDL) presents amyloid-like structural properties, and different amyloid species have recently been recognized in atherosclerotic plaques. Therefore, we studied the uptake of the amyloid imaging agent [18F]Flutemetamol in atherosclerotic plaques. The binding of [18F]Flutemetamol to human carotid artery plaque was studied in vitro. In vivo uptake of the tracer was studied in hypercholesterolemic IGF-II/LDLR?/?ApoB100/100 mice and C57BL/6N controls. Tracer biodistribution was studied in vivo with PET/CT, and ex vivo by gamma counter and digital ex vivo autoradiography. The presence of amyloid, ox-LDL, and macrophages in the plaques was examined by immunohistochemistry. [18F]Flutemetamol showed specific accumulation in human carotid plaque, especially in areas positive for amyloid beta. The aortas of IGF-II/LDLR?/?ApoB100/100 mice showed large thioflavin-S-positive atherosclerotic plaques containing ox-LDL and macrophages. Autoradiography revealed 1.7-fold higher uptake in the plaques than in a lesion-free vessel wall, but no difference in aortic tissue uptake between mouse strains were observed in the in vivo PET/CT. In conclusion, [18F]Flutemetamol binds to amyloid-positive areas in human atherosclerotic plaques. Further studies are warranted to clarify the uptake mechanisms, and the potential of the tracer for in vivo imaging of atherosclerosis in patients.

If you are interested in 566169-93-5, you can contact me at any time and look forward to more communication.Synthetic Route of 566169-93-5

Reference：
Thiazole | C3H477NS – PubChem,
Thiazole | chemical compound | Britannica