Tag: M.W=500-550

Vipotnik, Ziva published the artcileRehabilitation of a historically contaminated soil by different laccases and laccase-mediator system, HPLC of Formula: 30931-67-0, the publication is Journal of Soils and Sediments (2022), 22(5), 1546-1554, database is CAplus.

In this study, the degradation of polyaromatic hydrocarbons (PAH) present in naturally contaminated soil by laccases was evaluated. For that purpose, laccase was produced by solid-state fermentation (SSF) on agroindustrial residues by Trametes versicolor and Agrocybe aegerita. At the same time, com. laccases from T. versicolor and Aspergillus sp. (Novozym 51,003) were used. Material and methods: Contaminated soil was collected at a dumping site in Lagos, Nigeria, 15-30 cm depth, with a total measurement of 74.87 mg kg-1 of PAH (UHPLC) and 235.26 mg kg-1 of metals (ICP). Soil rehabilitation was evaluated in amber bottles containing 20 g contaminated soil, 20 mL of 10 U g-1 of different laccases and 1 mM of mediators (ABTS, ferulic and coumaric acid) for 12 days. Results and discussion: After 12 days of treatment with laccases and mediators, the total PAH in soil was reduced to 28.20 mg kg-1 and 33.40 mg kg-1 by the laccases from A. aegerita and T. versicolor strains studied in this work, resp., and to 42.23 mg kg-1 and 39.46 mg kg-1 by the action of the com. laccases from T. versicolor laccase and Aspergillus sp., resp. Despite redox mediators such as 2,2′-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS), ferulic acid and coumaric acid were studied; it was observed that laccase alone could also achieve high degradation of the contaminants load. In general, ABTS and ferulic acid were the most effective mediators in PAH degradation Despite the high price, laccases and laccase-mediator system (LMS) may degrade or transform different pollutants in real environment and work very efficiently in a first approach to the rehabilitation of soil.

Journal of Soils and Sediments published new progress about 30931-67-0. 30931-67-0 belongs to thiazole, auxiliary class Salt,Hydrazine,Amine,Benzothiazole, name is Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), and the molecular formula is C5H6N2O2, HPLC of Formula: 30931-67-0.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica

Wang, Dan published the artcileDegradation of octylphenol polyethoxylates with a long ethoxylate chain using the laccase-mediated systems, Name: Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), the publication is Environmental Science and Pollution Research (2021), 28(28), 37781-37792, database is CAplus and MEDLINE.

Alkylphenol polyethoxylates (APEO_n) are the second-largest category of com. nonionic surfactants, which are difficult to degrade naturally in the environment. This study examined the degradation of octylphenol polyethoxylate (OPEO_n) by laccase and its laccase-mediated systems. The results showed that OPEO_n was poorly degraded by laccase alone. 2, 2′-azino-bis [3-ethylbenzothiazoline-6-sulfonic acid] (ABTS), 1-hydroxybenzotriazole (HBT), and 2, 2, 6, 6-tetramethylpiperidine-1-oxyl (TEMPO) were selected as the redox mediators. Exptl. results also indicated that 52.4% of the initial OPEO_n amount was degraded by laccase in the presence of TEMPO. The degradation efficiency was analyzed using high-performance liquid chromatog. Furthermore, the structural characteristics of the degradation products were measured using matrix-assisted laser desorption/ionization-time of flight mass spectrometry and NMR spectroscopy, and it could be found that the laccase-TEMPO system could gradually shorten the ethoxylate chain by oxidizing the primary hydroxyl group of OPEO_n, thereby degrading the OPEO_n of the macromol. into small mols. The maximum of the ion peak distributions of OPEO_n decreased from n = 8 finally down to 3. The novel enzymic system introduced by this study will become a promising alternative method for high-efficiency APEO_n conversion and had great potential value in wastewater treatment.

Environmental Science and Pollution Research published new progress about 30931-67-0. 30931-67-0 belongs to thiazole, auxiliary class Salt,Hydrazine,Amine,Benzothiazole, name is Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), and the molecular formula is C7H11Br, Name: Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate).

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica

Wang, Jing published the artcileLabel-free colorimetric detection of acid phosphatase and screening of its inhibitors based on biomimetic oxidase activity of MnO₂ nanosheets, Quality Control of 30931-67-0, the publication is ACS Biomaterials Science & Engineering (2020), 6(5), 3132-3138, database is CAplus and MEDLINE.

In this research, we attempted to develop a sensitive colorimetric sensing strategy for the detection of acid phosphatase (ACP) based on MnO₂ nanosheets and explored its applications in screening and evaluating inhibitors of ACP. The MnO₂ nanosheets exhibit intrinsic biomimetic oxidase activity, which can catalyze the oxidation of the colorless 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonate) diammonium salt (ABTS) into green oxidized ABTS (oxABTS). Upon the introduction of ACP, L-ascorbic acid-2-phosphate can be dephosphorylated to ascorbic acid, which arouses the disintegration of MnO₂ nanosheets into Mn²⁺ ions. This disintegration weakens the enzyme mimicking activity of the MnO₂ nanosheets, leading to the impediment of the oxidation of ABTS. Conversely, in the absence of ACP, the ABTS is rapidly oxidized by MnO₂, leading to a significant colorimetric signal change. The absorbance difference at 420 nm displayed a linear relationship with the concentration of ACP ranging from 0.075 to 0.45 mU·mL^-1, generating a detection limit of 0.046 mU·mL^-1. In the inhibition assays, this sensing platform provided simple detection for parathion-Me (PM), a representative inhibitor of ACP. The facile evaluation of the inhibitory effect of PM, including its IC₅₀ toward ACP, was also realized.

ACS Biomaterials Science & Engineering published new progress about 30931-67-0. 30931-67-0 belongs to thiazole, auxiliary class Salt,Hydrazine,Amine,Benzothiazole, name is Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), and the molecular formula is C5H6BNO2, Quality Control of 30931-67-0.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica

Tang, Yin published the artcileStudy on chemical components, antioxidant activity and cognitive improvement of borneol essential oil, Computed Properties of 30931-67-0, the publication is Riyong Huaxue Gongye (2021), 51(11), 1095-1101, database is CAplus.

Gas chromatog.-mass spectrometry (GC-MS) technol. was used to detect chem. compositions and their relative contents of borneol essential oil. By analyzing scavenging activity of 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical and 2,2′-azinobis[3-ethylbenzothiazoline-6-sulfonicacid]-diammonium salt (ABTS) free radical, the antioxidant activity of borneol essential oil and trolox were determined in vitro. In order to explore the effect of borneol essential oil on behavior of mice with learning and memory impairment, Morris water maze test and immunohistochem. experiment were used to judge the cognitive function of mice in normal group, model group, borneol essential oil group and pos. group. In addition, after completing the animal behavior experiment, the levels of superoxide dismutase (SOD), glutathione peroxidase (GSH-PX) and malondialdehyde (MDA) of brain tissue were measured. The results showed that there were 43 main chem. components in borneol essential oil, such as borneol, D-limonene and 1,8-cineole. Free radical scavenging experiment finds that a certain concentration of borneol essential oil can effectively clean up DPPH and ABTS free radical, but its scavenging ability is less than trolox. The half maximal inhibitory concentration (IC₅₀) of borneol essential oil on DPPH and ABTS free radical were 1.65 and 2.27 g/L, resp. In Morris water maze, compared to mice in model group, the escape latency and crossing times of mice in borneol essential oil group were improved, and the performance of mice in borneol essential oil group was close to that in pos. group. In immunohistochem. experiment, the immunohistochem. section indicated that compared to mice in model group, the β-amyloid protein of mice in borneol essential oil group decreased, and the situation of mice in borneol essential oil group was close to that in pos. group. Compared to mice in model group, the activities of SOD and GSH-PX increased, and the content of MDA decreased in brain tissue of mice in borneol essential oil group. In conclusion, borneol essential oil has certain antioxidant activity in vitro and in vivo, and can improve cognitive impairment in mice.

Riyong Huaxue Gongye published new progress about 30931-67-0. 30931-67-0 belongs to thiazole, auxiliary class Salt,Hydrazine,Amine,Benzothiazole, name is Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), and the molecular formula is C6H6N2O, Computed Properties of 30931-67-0.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica

Gong, Xiaobei published the artcileProduction of Red Pigments by a Newly Isolated Talaromyces aurantiacus Strain with LED Stimulation for Screen Printing, Name: Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), the publication is Indian Journal of Microbiology (2022), 62(2), 280-292, database is CAplus and MEDLINE.

Microbial pigments have been widely applied to printing in food, textile, and paper industries as a sustainable alternative to synthetic dyes. Herein, we isolated a novel Talaromyces aurantiacus strain with a strong ability to produce red pigments. We further studied pigment production conditions, stability, screen printing application, and bioactivities. Our results showed that sucrose was a favorable carbon source and the addition of L-histidine significantly enhanced the production of red pigments. Pigment production was strictly photo-regulated with effective wavelengths around 450 nm (blue light). We mixed the red pigments with cellulosic materials and explored their application potentials for screen printing on paper, cotton fabrics, and polymeric carriers. The printing d. was significantly improved from 0.3 to 0.7 by overlay printing. T. aurantiacus pigments could be stably stored at pH 5-11, temperature – 10 to 70°C, and redox potential – 200 to 300 mV. Moreover, the stable ranges were extended to pH 1-11 and temperature over 100°C after screen-printed on paper. The red pigments exhibited antioxidant activity toward 2,2′-Azinobis-(3-ethylbenzthiazoline-6-sulfonate) (IC₅₀ 10.4 mg L^-1 in solution). Our results further indicated the red pigments by T. aurantiacus was environmentally friendly based on acetylcholinesterase activity assay.

Indian Journal of Microbiology published new progress about 30931-67-0. 30931-67-0 belongs to thiazole, auxiliary class Salt,Hydrazine,Amine,Benzothiazole, name is Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), and the molecular formula is C18H24N6O6S4, Name: Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate).

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica

Wu, Dingsheng published the artcileBiomass-derived nanocellulose aerogel enable highly efficient immobilization of laccase for the degradation of organic pollutants, Safety of Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), the publication is Bioresource Technology (2022), 127311, database is CAplus and MEDLINE.

Laccase is a promising biocatalyst for pollutant degradation and water purification However, laccase can only improve the stability of enzyme activity and achieve its significant catalytic effect after effective immobilization. Herein, we report a general strategy to integrate nanocellulose aerogel and laccase for high-efficiency degradation of organic pollutants. Biomass-derived functional bacterial cellulose (BC) aerogel with a nanonetwork structure and high porosity was prepared by biosynthesis, solvent replacement, and atom transfer radical polymerization (ATRP) procedures. Subsequently, a biocatalyst platform was fabricated by “coupling” ATRP-modified BC aerogel with abundant active sites with laccase through ion coordination. The results demonstrated the biocatalyst platform not only has good biol. affinity, but also has high enzyme load and structural stability. Meanwhile, the degradation rates of reactive red X-3B and 2, 4-dichlorophenol reached 94.5% and 85.2% within 4 h, resp. The strategy disclosed herein could provide a practical method for the degradation of organic pollutants.

Bioresource Technology published new progress about 30931-67-0. 30931-67-0 belongs to thiazole, auxiliary class Salt,Hydrazine,Amine,Benzothiazole, name is Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), and the molecular formula is C8H14O2, Safety of Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate).

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica

Tsilo, Phakamani Hopewell published the artcileChemical composition and some biological activities of the methanolic Encephalartos ferox fruit extract, Application In Synthesis of 30931-67-0, the publication is Pharmacognosy Journal (2020), 12(5), 1190-1197, database is CAplus.

Although literature reports the therapeutic properties of Encephalartos ferox, there are limited pharmacol. studies of its fruit. This study sought to evaluate the antibacterial, antioxidant, anti-quorum sensing, and in vitro cytotoxic activities of the methanolic E. ferox fruit extract The chem. constituent of the methanolic fruit extract was analyzed using gas chromatog.-mass spectrometry. Antibacterial activity of the extract was investigated against Staphylococcus aureus (ATCC 25923), Bacillus cereus (ATCC 10102), Escherichia coli (ATCC 25922) and Pseudomonas aeruginosa (ATCC 27853) using the broth dilution method. The standard 2.2-diphenyl-1-picrylhydrazyl (DPPH) and 2.2-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) methods were used to evaluate the scavenging activities of the extract Anti-quorum sensing activity was assessed against biosensor strain-Chromobacterium violaceum (ATCC 12472). Cytotoxicity in HepG2 cells was investigated using the tetrazolium-based colorimetric (MTT) assay. The extract revealed eight volatile compounds with cis-Vaccenic acid (87.06%) and 9-Octadecenoic acid, 1,2,3-propanetriyl ester (5.21%) as the major components. Antibacterial activity against all tested strains with min. inhibitory concentration range of 1.56 – 12.5 mg/mL was observed The DPPH and ABTS assays demonstrated scavenging activities with the median inhibitory concentration (IC₅₀) values of 0.09 mg/mL and 0.003 mg/mL, resp. The extract also displayed strong anti-quorum sensing activity with 93% inhibition of violacein production at 25 mg/mL. A half maximum inhibitory concentration (IC₅₀) of 5370 μg/mL was computed in HepG2 cells. The extract has potential to be used as a source of therapeutic compounds in pharmaceutical applications.

Pharmacognosy Journal published new progress about 30931-67-0. 30931-67-0 belongs to thiazole, auxiliary class Salt,Hydrazine,Amine,Benzothiazole, name is Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), and the molecular formula is C12H25Br, Application In Synthesis of 30931-67-0.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica

Jiang, Zhengxing published the artcileBlue Light-Gated Reversible Silver Nanozyme Reaction Networks that Achieve Life-like Adaptivity, Product Details of C18H24N6O6S4, the publication is ACS Sustainable Chemistry & Engineering (2020), 8(13), 5076-5081, database is CAplus.

Life is preserved by complex enzymic reaction systems. Inspired by life, here the authors report on the first example to fabricate blue light-gated reversible silver nanozyme reaction networks that achieve life-like adaptivity. Upon blue light excitation, silver nanoparticles (AgNPs) display oxidase-like activity in the presence of Cl^– as a cofactor. The addition of Cl^– promotes the separation between hot holes and electrons that are generated by excited-state surface plasmon of AgNPs, inducing the generation of highly reactive hydroxyl and superoxide anion radicals. They oxidize colorless 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)diammonium salt (ABTS) to yield green ABTS radicals (ABTS^•+). It is shown that ABTS^•+ is able to be reduced by AgNPs to regenerate ABTS when the blue light is turned off, and the reaction system returns to its initial state, which is the typical feature of the artificial adaptive system. The dynamic process of the adaptive system is tunable by changing the concentrations of AgNPs and Cl^–, and it possesses excellent recyclable performance, which can be repeated at least six times. Overall, the silver nanozyme reaction networks are capable of responding to blue light stimuli and renewing by recycling to the initial state without blue light irradiation Inspired by enzymic reaction systems, blue light-gated reversible silver nanozyme reaction networks that achieve life-like adaptivity are successfully constructed.

ACS Sustainable Chemistry & Engineering published new progress about 30931-67-0. 30931-67-0 belongs to thiazole, auxiliary class Salt,Hydrazine,Amine,Benzothiazole, name is Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), and the molecular formula is C18H24N6O6S4, Product Details of C18H24N6O6S4.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica

Li, Peng published the artcileA label-free and signal-amplifiable assay method for colorimetric detection of carcinoembryonic antigen, Related Products of thiazole, the publication is Biotechnology and Bioengineering (2022), 119(2), 504-512, database is CAplus and MEDLINE.

In this work, an innovative colorimetric assay method for the determination of carcinoembryonic antigen is developed with aptamer probes utilized as recognition element. DNA hybridization chain reaction is used as signal amplification technique, and peroxidase-mimicking hemin/G-quadruplex-assisted catalytic oxidation of 2,2′-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) is deployed as signal reporting mechanism. The detection principle was firstly verified by using gel electrophoresis anal. and absorbance measurements. After condition optimization, a detection limit was theor. determined as 24.8 ng/mL. Furthermore, the method exhibited good selectivity and satisfactory recovery rates (92.2%-108.6%) in serum samples. Moreover, the sensing scheme is easily extended for the detection of other analytes via similar target-aptamer recognition principle. To sum up, this is an enzyme- and label-free, cost-effective yet signal-amplifiable assay scheme for the determination of tumor markers with promising simplicity and selectivity, practical utility, and potential universality.

Biotechnology and Bioengineering published new progress about 30931-67-0. 30931-67-0 belongs to thiazole, auxiliary class Salt,Hydrazine,Amine,Benzothiazole, name is Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), and the molecular formula is C18H24N6O6S4, Related Products of thiazole.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica

Yan, Bingsong published the artcileColorimetric detection of acetylcholinesterase and its inhibitor based on thiol-regulated oxidase-like activity of 2D palladium square nanoplates on reduced graphene oxide, Product Details of C18H24N6O6S4, the publication is Microchimica Acta (2021), 188(5), 162, database is CAplus and MEDLINE.

A convenient and sensitive colorimetric assay for acetylcholinesterase (AChE) and its inhibitor has been designed based on the oxidase-like activity of {100}-faceted Pd square nanoplates which are grown in situ on reduced graphene oxide (PdSP@rGO). PdSP@rGO can effectively catalyze the oxidation of colorless 3,3′,5,5′-tetramethylbenzidine (TMB) without the assistance of H₂O₂ to generate blue oxidized TMB (oxTMB) with a characteristic absorption peak at 652 nm. In the presence of AChE, acetylthiocholine (ATCh), a typical AChE substrate, is hydrolyzed to thiocholine (TCh). The generated TCh can effectively inhibit the PdSP@rGO-triggered chromogenic reaction of TMB via cheating with Pd, resulting in color fading and decrease in absorbance. Thus, a sensitive probe for AChE activity is constructed with a working range of 0.25-5 mU mL-1 and a limit of detection (LOD) of 0.0625 mU mL-1. Furthermore, because of the inhibition effect of tacrine on AChE, tacrine is also detected through the colorimetric AChE assay system within the concentrations range 0.025-0.4μM with a LOD of 0.00229μM. Hence, a rapid and facile colorimetric procedure to sensitively detect AChE and its inhibitor can be anticipated through modulating the oxidase-like activity of PdSP@rGO.

Microchimica Acta published new progress about 30931-67-0. 30931-67-0 belongs to thiazole, auxiliary class Salt,Hydrazine,Amine,Benzothiazole, name is Ammonium 2,2′-(hydrazine-1,2-diylidene)bis(3-ethyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate), and the molecular formula is C11H10O, Product Details of C18H24N6O6S4.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/thiazole,
Thiazole | chemical compound | Britannica