Studies on synthesis of 6-bromo-2,3-disubstituted 4(3H)-quinazolinones and their thiones was written by Badr, Mahmoud Zarif Amin;El-Sherief, Hassan Ahmed Hassan;Mahmoud, Abdallah Mohamed. And the article was included in Bulletin of the Chemical Society of Japan in 1980.Category: thiazole This article mentions the following:
Some 2,3-disubstituted 6-bromo-4(3H)-quinazolinones were prepared Treatment of 4-quinazolinones with P2S5 gave the corresponding 4-quinazolinethiones. The reaction of 6-bromo-2-methyl-3,1-benzoxazin-4-one with NH2OH.HCl gave 6-bromo-3-hydroxy-2-methyl-4(3H)-quinazolinone, which on treatment with alkyl halides, acyl chlorides and sulfonyl chlorides gave the corresponding ethers, esters, and sulfonates. 2-Styryl-4(3H)-quinazolinone derivatives are obtained by condensation of aromatic aldehydes with 3-substituted-6-bromo-2-methyl-4(3H)-quinazolinones. Some title compounds have considerable bactericidal activity. In the experiment, the researchers used many compounds, for example, 4,5-Diphenylthiazol-2-amine (cas: 6318-74-7Category: thiazole).
4,5-Diphenylthiazol-2-amine (cas: 6318-74-7) belongs to thiazole derivatives. The thiazole ring has been identified as a central feature of numerous natural products, perhaps the most famous example of which is epothilone.Various laboratory methods exist for the organic synthesis of thiazoles. For example, 2,4-dimethylthiazole is synthesized from thioacetamide and chloroacetone.Category: thiazole
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica