Synthesis of 2-mercaptobenzothiazole using nitrobenzene and H2S as starting materials was written by Li, Jinghua;Li, Zhenqiu;Yu, Guang;Song, Yuye. And the article was included in Qingdao Keji Daxue Xuebao, Ziran Kexueban in 2009.Reference of 1843-21-6 This article mentions the following:
H2S which was the byproduct from 2-mercaptobenzothiazole synthesis process reacted with nitrobenzene to prepare aniline and the obtained aniline was directly used to synthesize 2-mercaptobenzothiazole. The sulfur obtained from reduction process was used as material for synthesizing 2-mercaptobenzothiazole. That is to say the byproducts H2S and sulfur could be utilized circularly. Under the conditions of 80-100°C, certain pressure and 3-4 h, the yield of aniline could reach 6.619%. The feasibility of experiment was done by directly adding sulfur dissolved in carbon disulfide into the reduction mixture to prepare 2- mercaptobenzothiazole. A new clean synthesis method of 2-mercaptobenzothiazole with lower cost is explored. In the experiment, the researchers used many compounds, for example, N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6Reference of 1843-21-6).
N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6) belongs to thiazole derivatives. Thiazole rings are planar and aromatic. Thiazoles are characterized by larger pi-electron delocalization than the corresponding oxazoles and have therefore greater aromaticity. The pyridine-type nitrogen in the thiazole ring deactivates the ring for electrophilic substitution reactions, which is further reduced in acid due to protonation of the thiazole ring.Reference of 1843-21-6
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica