Postsynthetic modification of IRMOF-3 with a copper (imino)pyridine complex as heterogeneous catalyst for the synthesis of 2a[̂n.128]aminobenzothiazoles was written by Liu, Jie;Zhang, Xiaobin;Yang, Jin;Wang, Lei. And the article was included in Applied Organometallic Chemistry in 2014.Category: thiazole This article mentions the following:
A copper imine-pyridine complex was immobilized on to a metal-organic framework (MOF) by a h postsynthetic modification of IRMOF-3. The modified MOFs were fully demonstrated by using a variety of methods and the structural integrity of the modified MOFs was confirmed by powder X-ray diffraction (XRD). Furthermore, it was shown that the modified IRMOF-3 can act as an efficient solid catalyst for the synthesis of 2-aminobenzothiazoles via the reaction of 2-iodoanilines with isothiocyanates in a heterogeneous manner. Moreover, the catalyst could be easily separated from the reaction mixture and reused for six consecutive cycles without significant degradation in catalytic activity. The synthesis of the target compound (catalyst) was achieved by a reaction of (amino)benzenedicarboxylic acid and zinc nitrate reaction product [i.e, isoreticular metal-organic framework (IRMOF-3)] with 2-pyridinecarboxaldehyde, thus providing an isoreticular metal-organic framework (IRMOF-3) supported N-[(pyridinyl)methylene]benzenamine (Schiff base imine) which underwent complexation with copper iodide (CuI). The product was copper-N-[(pyridinyl)methylene]benzenamine (Schiff base imine) complex supported on isoreticular metal-organic framework (IRMOF-3). Starting materials included (isothiocyanato)benzene (isothiocyanate), 2-iodobenzenamine derivatives (aryl iodides, iodo aniline derivatives), 1-isothiocyanato-3,5-bis(trifluoromethyl)benzene, etc. The title compounds thus formed included N-phenyl-2-benzothiazolamine derivatives and related substances, such as 6-fluoro-N-(4-methylphenyl)-2-benzothiazolamine, N-(4-chlorophenyl)-6-(trifluoromethyl)-2-benzothiazolamine. Copyright 2014 John Wiley & Sons, Ltd. In the experiment, the researchers used many compounds, for example, N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6Category: thiazole).
N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6) belongs to thiazole derivatives. Thiazoles frequently appear in peptide studies. Thiazoles can also be used as protected formyl groups, which can be released in later stages of complex natural product synthesis. Various laboratory methods exist for the organic synthesis of thiazoles. Prominent is the Hantzsch thiazole synthesis is a reaction between haloketones and thioamides.Category: thiazole
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica