Ruthenium-Catalyzed Oxidative Annulation of Anilines using Benzothiazole as a Removable Directing Group was written by Sharma, Shivani;Singh, Sukanya;Kumari, Akhilesh;Sawant, Devesh M.;Pardasani, Ram T.. And the article was included in Asian Journal of Organic Chemistry in 2017.Recommanded Product: N-Phenylbenzo[d]thiazol-2-amine This article mentions the following:
An efficient and inexpensive cationic ruthenium(II) catalyst enabled synthesis of bis-heterocycles I (R1 = H, 6-Cl, 6-Br, 6-CN, 5-Cl; R2 = H, 5-Me, 6-NO2, etc.; R3 = R4 = Ph, Et, 4-methoxyphenyl, etc.; R3 = Ph, CH3C(O)OCH2CH3; R4 = H, CH3, CH2CH3, 4-H3COC6H4) through an oxidative annulation of benzothiazole-directed anilines II (R6 = H, 4-CH3, 3-Cl, etc.) and alkynes R3CCR4 is described. This strategy provides a broad scope of anilines bearing a directing group and alkynes with good to excellent yields. This is the first report on benzothiazoles as removable directing groups, leading to the construction of diversified indoles III. In the experiment, the researchers used many compounds, for example, N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6Recommanded Product: N-Phenylbenzo[d]thiazol-2-amine).
N-Phenylbenzo[d]thiazol-2-amine (cas: 1843-21-6) belongs to thiazole derivatives. Thiazole rings are planar and aromatic. Thiazoles are characterized by larger pi-electron delocalization than the corresponding oxazoles and have therefore greater aromaticity. The pyridine-type nitrogen in the thiazole ring deactivates the ring for electrophilic substitution reactions, which is further reduced in acid due to protonation of the thiazole ring.Recommanded Product: N-Phenylbenzo[d]thiazol-2-amine
Referemce:
Thiazole | C3H3NS – PubChem,
Thiazole | chemical compound | Britannica